DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and vasna

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_001313614.1	Gene:	vasna / 553185	ZFINID:	ZDB-GENE-050522-43	Length:	688	Species:	Danio rerio

Alignment Length:	344	Identity:	101/344 - (29%)
Similarity:	145/344 - (42%)	Gaps:	81/344 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 INV-HTNGFSILPNLRQLNLSGCGLVDIRGNHFAPESALQRIDFSHNQMELLDRDFFGNLRKLIY 156
            ||: ....|..|..|..|:||...|.:|....|:|.|:|..:|.|.|.:..:.:|.|
Zfish    64 INILQQQDFVELGELEMLDLSQNSLSEIPDGVFSPLSSLHNLDLSSNYITHISKDSF-------- 120

  Fly   157 ANFSHNALKQCDLPHMPLLNRLELGHNRLVNATFGVCPQLQELILNDNQLIQLDVNAFRGLHGLL 221
                                   :|   |||        |:.|.|..|.:..:...||.||..||
Zfish   121 -----------------------IG---LVN--------LERLYLYSNIIQNIHPAAFEGLENLL 151

  Fly   222 ELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQLDLSGNRIRLLF 286
            ||:|.||::|.  |...| |.:|..|:||.|::.   |.|...:|  ..||:.|.::|..:..|.
Zfish   152 ELKLQGNQISV--LPALQ-LPRLLHLDLSYNSIP---PLVAQDLQ--TPHLESLKIAGLGLTSLD 208

  Fly   287 DNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDLSY 351
            :.....|..|.:||||:|.:..:.|. ...:|.||.|.|..|.:..:|...|..|:||..||||.
Zfish   209 EELLGSLVNLHVLDVSQNQLVDIQPT-LKSMGGLRNLNLTGNPLGSLKHEDFQNLVNLLELDLSN 272

  Fly   352 NNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSLDVRM----- 411
            .||:...|..|  |..|::.:|....|....|.|||:    |..:||         |||:
Zfish   273 LNLQGFPEGFF--NLFPKLEKLTAAENPFNCLCPLAW----FPAWLK---------DVRVELLRT 322

  Fly   412 ------FAPM---RRLQKL 421
                  |.|:   :.|:||
Zfish   323 EETRCHFPPINSGKVLEKL 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	44/152 (29%)
		LRR_8	104..164	CDD:290566	15/59 (25%)
		leucine-rich repeat	106..129	CDD:275380	8/22 (36%)
		leucine-rich repeat	130..153	CDD:275380	6/22 (27%)
		leucine-rich repeat	154..195	CDD:275380	4/40 (10%)
		LRR_RI	194..455	CDD:238064	78/242 (32%)
		LRR_8	194..254	CDD:290566	24/59 (41%)
		leucine-rich repeat	196..219	CDD:275380	8/22 (36%)
		leucine-rich repeat	220..243	CDD:275380	11/22 (50%)
		leucine-rich repeat	244..267	CDD:275380	7/22 (32%)
		LRR_8	271..330	CDD:290566	19/58 (33%)
		leucine-rich repeat	272..295	CDD:275380	5/22 (23%)
		leucine-rich repeat	296..319	CDD:275380	7/22 (32%)
		LRR_8	319..380	CDD:290566	22/60 (37%)
		leucine-rich repeat	320..343	CDD:275380	8/22 (36%)
		leucine-rich repeat	344..369	CDD:275380	10/24 (42%)
		LRR_8	368..428	CDD:290566	18/68 (26%)
		leucine-rich repeat	370..393	CDD:275380	6/22 (27%)
		leucine-rich repeat	394..417	CDD:275380	7/36 (19%)
		leucine-rich repeat	418..441	CDD:275380	3/4 (75%)
vasna	NP_001313614.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910