DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6749 and AgaP_AGAP005668

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	XP_001237694.1	Gene:	AgaP_AGAP005668 / 4576765	VectorBaseID:	AGAP005668	Length:	405	Species:	Anopheles gambiae

Alignment Length:	385	Identity:	92/385 - (23%)
Similarity:	152/385 - (39%)	Gaps:	96/385 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 SILPNLRQLNLSGCGLVDIRGNHFAPESALQRIDFSHNQMELLDRDFFGNLRKLIYANFSHNALK 165
            |:...|:.|::.   |..:|...|...|.|:.:..::.|:..|. |...:...|::...:...::
Mosquito    91 SVPQTLKALSIE---LTRLRRIEFEANSTLKHLMIAYCQLSTLP-DAIQHAPMLLHLQITSCNIQ 151

  Fly   166 QCDLPHM---PLLNRLELGHNRL---VNATFGVCPQLQELILNDNQLIQLDVNAFRGLHGLLELQ 224
            |.|:..:   .||:.:.|..|:|   .|.:...|      .|.|:               |..|.
Mosquito   152 QLDMASLCENALLSTVILTRNKLRYIANTSTKQC------ALYDS---------------LSALV 195

  Fly   225 LSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQLDLSGNRIRLLFDNQ 289
            |:||||.||.:|.|....:|..:.|..|.:.:|....   |.|.:..| ::|:  ||:..:...|
Mosquito   196 LTGNRLKSINMELFNGFVRLDSVFLQSNRITSLAGRF---VHNAIAEL-RMDI--NRLAWVDLCQ 254

  Fly   290 FRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDLSYNNL 354
            :.|.| |..|....|.:|.: |.....|.::.:|.|..|.:......:.|.:.:|.:|.||||.|
Mosquito   255 WSVPA-LVWLSFDENVLAEV-PKCMNNLKNITRLVLSSNVLSNFTIESVAGMEHLVSLSLSYNQL 317

  Fly   355 EFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSLDVRMFAPMRRLQ 419
                            ..:.||..|....          ||::.|.||.|.|||: .|.|:|.|:
Mosquito   318 ----------------LSVTLNSERFPRR----------LEFINLYHNNLTSLDL-SFIPVRSLK 355

  Fly   420 KLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKVNV--SFPNLKRVAIEGNPWQC 477
                                       :|.:| .|:|..:|  :..|:.|:|:|.||..|
Mosquito   356 ---------------------------IDASR-NFIASFDVHGTSANVSRLAMEHNPIDC 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	36/158 (23%)
		LRR_8	104..164	CDD:290566	11/59 (19%)
		leucine-rich repeat	106..129	CDD:275380	5/22 (23%)
		leucine-rich repeat	130..153	CDD:275380	4/22 (18%)
		leucine-rich repeat	154..195	CDD:275380	10/46 (22%)
		LRR_RI	194..455	CDD:238064	61/260 (23%)
		LRR_8	194..254	CDD:290566	16/59 (27%)
		leucine-rich repeat	196..219	CDD:275380	2/22 (9%)
		leucine-rich repeat	220..243	CDD:275380	11/22 (50%)
		leucine-rich repeat	244..267	CDD:275380	5/22 (23%)
		LRR_8	271..330	CDD:290566	16/58 (28%)
		leucine-rich repeat	272..295	CDD:275380	6/22 (27%)
		leucine-rich repeat	296..319	CDD:275380	6/22 (27%)
		LRR_8	319..380	CDD:290566	13/60 (22%)
		leucine-rich repeat	320..343	CDD:275380	4/22 (18%)
		leucine-rich repeat	344..369	CDD:275380	7/24 (29%)
		LRR_8	368..428	CDD:290566	16/59 (27%)
		leucine-rich repeat	370..393	CDD:275380	3/22 (14%)
		leucine-rich repeat	394..417	CDD:275380	11/22 (50%)
		leucine-rich repeat	418..441	CDD:275380	1/22 (5%)
AgaP_AGAP005668	XP_001237694.1	leucine-rich repeat	117..139	CDD:275380	4/22 (18%)
		leucine-rich repeat	164..190	CDD:275380	7/31 (23%)
		LRR_8	190..247	CDD:290566	20/77 (26%)
		leucine-rich repeat	191..214	CDD:275380	11/22 (50%)
		leucine-rich repeat	215..259	CDD:275380	12/49 (24%)
		leucine-rich repeat	260..282	CDD:275380	6/22 (27%)
		LRR_8	281..341	CDD:290566	19/85 (22%)
		leucine-rich repeat	283..306	CDD:275380	4/22 (18%)
		leucine-rich repeat	307..330	CDD:275380	10/38 (26%)
		leucine-rich repeat	354..365	CDD:275378	4/38 (11%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910