DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and Tollo

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:NP_524757.1 Gene:Tollo / 44497 FlyBaseID:FBgn0029114 Length:1346 Species:Drosophila melanogaster


Alignment Length:558 Identity:154/558 - (27%)
Similarity:244/558 - (43%) Gaps:103/558 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 ANWVLPLLLWLLCMGFPILHGA-DLCQPIGWRNFQCSEVASLQDL-VDLGAENWHTLAIRN-VQT 66
            |..|:|  ::...:...:|:.| |.|:..|......:.|..|:.: .:|...|:..:..:| |:.
  Fly    13 ATCVIP--IFGAALSKTVLYQAPDECRWSGGGEHDITLVCHLRTINSELENTNFSVIQPQNTVRL 75

  Fly    67 ELEVG------SGENADHLANLLDL-DLT------GAAPINVHTNGFSILPNLRQLNL------- 111
            .||..      |..:.|...:|::| |||      |    |:....|..|..||.|.:       
  Fly    76 RLECNDALFFQSSLSPDSFRSLVELRDLTIEYCKLG----NLTDGSFRGLQELRNLTIRTHNGDW 136

  Fly   112 SGCGLVDIRGNHFAPESALQRIDFSHNQMELLDRDFFGNLRKLIYANFSHNALKQCDLPHM---- 172
            |...| ::..|.|.....|:|:|.|.|.:.|:.......|:.|.:.|.|:|.::  |:.:.    
  Fly   137 STMSL-EMASNSFVEFRQLERLDLSLNNIWLIPDGMVCPLKSLQHLNASYNKIQ--DISNFYFSA 198

  Fly   173 -----------PLLNRLELGHNRLVN---ATFGVCPQLQELILNDNQLIQLDVNAFRGLHGLLEL 223
                       ..|..|:|..|::|:   |......:|..|.:..|.:..|...||.||..|..:
  Fly   199 SLSSRKARVCGSTLQSLDLSANKMVSLPTAMLSALGRLTHLNMAKNSMSFLADRAFEGLLSLRVV 263

  Fly   224 QLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQLDLSGNRIRLLFDN 288
            .||.|||:|:..|.|....||:::.|..|:::.|.|.:||.:...::    |||:.|.:...:.|
  Fly   264 DLSANRLTSLPPELFAETKQLQEIYLRNNSINVLAPGIFGELAELLV----LDLASNELNSQWIN 324

  Fly   289 --QFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDLSY 351
              .|..|.||.|||:|.|.|:.|....|..|.||:.|.|:.|.|.::....||.|.||.||.||.
  Fly   325 AATFVGLKRLMMLDLSANKISRLEAHIFRPLASLQILKLEDNYIDQLPGGIFADLTNLHTLILSR 389

  Fly   352 NNLEFLEEQIFGG-----------NTLPRM-----------RRLNLNGNRMKHLHPLAFSSLPFL 394
            |.:..:|::...|           |.:.||           :.|:||.|:::.: |.|.:.:..|
  Fly   390 NRISVIEQRTLQGLKNLLVLSLDFNRISRMDQRSLVNCSQLQDLHLNDNKLQAV-PEALAHVQLL 453

  Fly   395 EYLKLGHN-----------ELKSL-DVRM------------FAPMRRLQKLHLGHNLLEEINLDV 435
            :.|.:|.|           :|:|| .:||            |..|..||.|:|..|.|:.|....
  Fly   454 KTLDVGENMISQIENTSITQLESLYGLRMTENSLTHIRRGVFDRMSSLQILNLSQNKLKSIEAGS 518

  Fly   436 LESLSSVQEILVDNNRLTFLAKVNVSFPNLKRVAIEGN 473
            |:..|.:|.|.:|.|:|..:|.:....|||..:.|.||
  Fly   519 LQRNSQLQAIRLDGNQLKSIAGLFTELPNLVWLNISGN 556

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 47/177 (27%)
LRR_8 104..164 CDD:290566 18/66 (27%)
leucine-rich repeat 106..129 CDD:275380 7/29 (24%)
leucine-rich repeat 130..153 CDD:275380 7/22 (32%)
leucine-rich repeat 154..195 CDD:275380 11/58 (19%)
LRR_RI 194..455 CDD:238064 95/308 (31%)
LRR_8 194..254 CDD:290566 21/59 (36%)
leucine-rich repeat 196..219 CDD:275380 8/22 (36%)
leucine-rich repeat 220..243 CDD:275380 9/22 (41%)
leucine-rich repeat 244..267 CDD:275380 7/22 (32%)
LRR_8 271..330 CDD:290566 23/60 (38%)
leucine-rich repeat 272..295 CDD:275380 7/24 (29%)
leucine-rich repeat 296..319 CDD:275380 10/22 (45%)
LRR_8 319..380 CDD:290566 25/82 (30%)
leucine-rich repeat 320..343 CDD:275380 8/22 (36%)
leucine-rich repeat 344..369 CDD:275380 9/35 (26%)
LRR_8 368..428 CDD:290566 24/94 (26%)
leucine-rich repeat 370..393 CDD:275380 7/33 (21%)
leucine-rich repeat 394..417 CDD:275380 11/46 (24%)
leucine-rich repeat 418..441 CDD:275380 8/22 (36%)
TolloNP_524757.1 LRR_RI <85..281 CDD:238064 53/202 (26%)
leucine-rich repeat 100..123 CDD:275380 8/26 (31%)
leucine-rich repeat 124..144 CDD:275380 5/20 (25%)
LRR_8 152..222 CDD:290566 16/71 (23%)
leucine-rich repeat 154..177 CDD:275380 7/22 (32%)
leucine-rich repeat 178..201 CDD:275380 5/24 (21%)
LRR 210..656 CDD:227223 108/352 (31%)
leucine-rich repeat 212..235 CDD:275380 6/22 (27%)
leucine-rich repeat 236..259 CDD:275380 8/22 (36%)
leucine-rich repeat 260..283 CDD:275380 9/22 (41%)
LRR_RI 276..558 CDD:238064 87/286 (30%)
leucine-rich repeat 284..307 CDD:275380 7/22 (32%)
leucine-rich repeat 308..333 CDD:275380 7/28 (25%)
leucine-rich repeat 334..357 CDD:275380 10/22 (45%)
leucine-rich repeat 358..381 CDD:275380 8/22 (36%)
leucine-rich repeat 382..405 CDD:275380 8/22 (36%)
leucine-rich repeat 406..429 CDD:275380 3/22 (14%)
leucine-rich repeat 430..452 CDD:275380 6/22 (27%)
leucine-rich repeat 453..500 CDD:275380 11/46 (24%)
leucine-rich repeat 501..521 CDD:275380 8/19 (42%)
leucine-rich repeat 525..547 CDD:275380 6/21 (29%)
leucine-rich repeat 548..573 CDD:275380 4/9 (44%)
leucine-rich repeat 604..640 CDD:275380
leucine-rich repeat 641..688 CDD:275380
leucine-rich repeat 689..816 CDD:275380
LRR_8 815..875 CDD:290566
leucine-rich repeat 817..864 CDD:275380
LRR_8 864..921 CDD:290566
leucine-rich repeat 865..888 CDD:275380
leucine-rich repeat 889..910 CDD:275380
TIR 1076..1211 CDD:214587
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453509
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.940

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