DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and trn

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_001261796.1	Gene:	trn / 39491	FlyBaseID:	FBgn0010452	Length:	751	Species:	Drosophila melanogaster

Alignment Length:	411	Identity:	111/411 - (27%)
Similarity:	178/411 - (43%)	Gaps:	79/411 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 GCGLVDIRGNHFAPESALQRIDFSHNQMELLDRDFFGNLRKLIYANFSHNALKQCDLPHMPLLNR 177
            |.|.:|:.  ..|...::||:....|:::.:|...      ..||.                |..
  Fly    46 GEGQLDVL--PIALNPSIQRLVIKSNKIKTIDSSI------QFYAE----------------LTF 86

  Fly   178 LELGHNRLV---NATFGVCPQLQELILNDNQLIQLDVNAFRGLHGLLELQLSGNRLSSIGLETFQ 239
            |:|..|.|:   ..||....:|||:.||.|::.|:....|.||..:..|.|.||::|.:...||.
  Fly    87 LDLSSNHLMTIPQRTFAYQKKLQEVHLNHNKIGQISNKTFIGLSAVTVLNLRGNQISELHQGTFT 151

  Fly   240 PLAQLRKLNLSQNALDALRPNVF-GAVQNFVLHLQ--------------------QLDLSGNRIR 283
            ||.::.:|||.:|.:..|.|..| |..|..:|:|.                    :|.|..|.::
  Fly   152 PLLKIEELNLGENRIGYLDPKAFDGLSQLRILYLDDNALTTVPDPVIFQAMPSLAELFLGMNTLQ 216

  Fly   284 LLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLD 348
            .:..:.|:.|..|..|::...|:.::|...|:||..||.|.|..|.:..|.....:.|:.|:.|.
  Fly   217 SIQADAFQDLKGLTRLELKGASLRNISHDSFLGLQELRILDLSDNRLDRIPSVGLSKLVRLEQLS 281

  Fly   349 LSYNNLEFLEEQIFGGNTLPRMRRLNLNGN-RMKHLHPLAFSSLPFLEYLKLGHNELKSLDVRMF 412
            |..|:.|.:.|..|.|  |.:::||.:||. |:|.:...|||....||||.|..|:
  Fly   282 LGQNDFEVISEGAFMG--LKQLKRLEVNGALRLKRVMTGAFSDNGNLEYLNLSSNK--------- 335

  Fly   413 APMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKVNVSFPNLKRVAIEGNPWQC 477
                          :|.|:....|..||.::.:::..|.||.||:....:.:|:.:.:..||..|
  Fly   336 --------------MLLEVQEGALSGLSQLKHVVLKANALTSLAEGLFPWKDLQTLDLSENPLSC 386

  Fly   478 PCFVKLQHWL-----ATRDVV 493
            .|.|...|.|     |::|.|
  Fly   387 DCRVMWLHNLLVAKNASQDDV 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	40/145 (28%)
		LRR_8	104..164	CDD:290566	10/50 (20%)
		leucine-rich repeat	106..129	CDD:275380	4/15 (27%)
		leucine-rich repeat	130..153	CDD:275380	4/22 (18%)
		leucine-rich repeat	154..195	CDD:275380	9/43 (21%)
		LRR_RI	194..455	CDD:238064	81/282 (29%)
		LRR_8	194..254	CDD:290566	23/59 (39%)
		leucine-rich repeat	196..219	CDD:275380	10/22 (45%)
		leucine-rich repeat	220..243	CDD:275380	9/22 (41%)
		leucine-rich repeat	244..267	CDD:275380	8/23 (35%)
		LRR_8	271..330	CDD:290566	18/78 (23%)
		leucine-rich repeat	272..295	CDD:275380	6/42 (14%)
		leucine-rich repeat	296..319	CDD:275380	7/22 (32%)
		LRR_8	319..380	CDD:290566	20/61 (33%)
		leucine-rich repeat	320..343	CDD:275380	7/22 (32%)
		leucine-rich repeat	344..369	CDD:275380	9/24 (38%)
		LRR_8	368..428	CDD:290566	15/60 (25%)
		leucine-rich repeat	370..393	CDD:275380	9/23 (39%)
		leucine-rich repeat	394..417	CDD:275380	6/22 (27%)
		leucine-rich repeat	418..441	CDD:275380	4/22 (18%)
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	4/23 (17%)
		LRR_8	83..142	CDD:290566	21/74 (28%)
		leucine-rich repeat	84..107	CDD:275380	7/22 (32%)
		leucine-rich repeat	108..131	CDD:275380	10/22 (45%)
		LRR_RI	129..421	CDD:238064	85/304 (28%)
		LRR_8	132..190	CDD:290566	20/57 (35%)
		leucine-rich repeat	132..155	CDD:275380	9/22 (41%)
		leucine-rich repeat	156..179	CDD:275380	8/22 (36%)
		leucine-rich repeat	180..204	CDD:275380	2/23 (9%)
		LRR_8	203..263	CDD:290566	17/59 (29%)
		leucine-rich repeat	205..228	CDD:275380	5/22 (23%)
		leucine-rich repeat	229..252	CDD:275380	7/22 (32%)
		LRR_8	252..308	CDD:290566	18/57 (32%)
		leucine-rich repeat	253..276	CDD:275380	7/22 (32%)
		leucine-rich repeat	277..300	CDD:275380	9/24 (38%)
		leucine-rich repeat	301..322	CDD:275380	8/20 (40%)
		LRR_8	325..384	CDD:290566	18/81 (22%)
		leucine-rich repeat	326..350	CDD:275380	10/46 (22%)
		leucine-rich repeat	351..373	CDD:275380	5/21 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472909
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840