DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and chad

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:NP_957357.1 Gene:chad / 394038 ZFINID:ZDB-GENE-040426-1130 Length:363 Species:Danio rerio


Alignment Length:373 Identity:99/373 - (26%)
Similarity:157/373 - (42%) Gaps:80/373 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   149 GNLRKLIYANFSHNALKQCDLPHMPLLNR-LELGHNRLVNATFGVCPQLQELI---LNDNQLIQL 209
            |:|:.:|..|.   .||:  :|.:....| |.|..|.|.|...|...:::.||   |...|:.:|
Zfish    35 GDLQHVICDNV---GLKK--IPRISEATRLLNLQRNNLGNLPTGGFSEMKGLISLHLQHCQIREL 94

  Fly   210 DVNAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQ 274
            ...||:||:.|:.|.||.|.:|:|....|:.|.:|..|.|..|.:.:|...:|..:.|..:    
Zfish    95 SGQAFKGLNKLIYLYLSDNEISTIKPGAFEDLTELTYLYLDGNQITSLPKGIFSPMINLFI---- 155

  Fly   275 LDLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFA 339
            |.|:.|::|                        .|.|..|.|...||.||:..|.:..|:|.:..
Zfish   156 LQLNNNKLR------------------------ELQPGTFKGAKDLRWLYMSGNELSSIQPGSLD 196

  Fly   340 ALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNEL 404
            .:.||..|.|..|||          :|.|.                ||.|.|..:|.|.|..|.|
Zfish   197 EVENLAILTLDQNNL----------STYPL----------------LAMSKLRVVEELNLSKNPL 235

  Fly   405 KSLDVRMFAPM-RRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKVNVSFPNLKRV 468
            ..:....|... |.::||||....||:.:....|.:::::.:.::||:|..|.. ::.|..::.:
Zfish   236 SLIPDHAFRSFGRYMEKLHLNDMSLEKFSNAAFEGVTALKSLHLENNKLRSLPN-SLEFSTIQNI 299

  Fly   469 AIEGNPWQCPC-FVKLQHWLATR----DVV----------YLRDNTGY 501
            .:..|||.|.| ...|:.|:.|.    |.|          .:||:|.:
Zfish   300 TLFNNPWSCTCPLTNLRKWMDTTRNRPDAVCASPANQKGKQIRDSTAF 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 36/110 (33%)
LRR_8 104..164 CDD:290566 4/14 (29%)
leucine-rich repeat 106..129 CDD:275380
leucine-rich repeat 130..153 CDD:275380 2/3 (67%)
leucine-rich repeat 154..195 CDD:275380 12/41 (29%)
LRR_RI 194..455 CDD:238064 70/264 (27%)
LRR_8 194..254 CDD:290566 22/62 (35%)
leucine-rich repeat 196..219 CDD:275380 9/25 (36%)
leucine-rich repeat 220..243 CDD:275380 9/22 (41%)
leucine-rich repeat 244..267 CDD:275380 6/22 (27%)
LRR_8 271..330 CDD:290566 13/58 (22%)
leucine-rich repeat 272..295 CDD:275380 4/22 (18%)
leucine-rich repeat 296..319 CDD:275380 4/22 (18%)
LRR_8 319..380 CDD:290566 16/60 (27%)
leucine-rich repeat 320..343 CDD:275380 7/22 (32%)
leucine-rich repeat 344..369 CDD:275380 7/24 (29%)
LRR_8 368..428 CDD:290566 16/60 (27%)
leucine-rich repeat 370..393 CDD:275380 4/22 (18%)
leucine-rich repeat 394..417 CDD:275380 6/23 (26%)
leucine-rich repeat 418..441 CDD:275380 7/22 (32%)
chadNP_957357.1 LRRNT 26..52 CDD:279764 6/21 (29%)
leucine-rich repeat 57..80 CDD:275380 7/22 (32%)
LRR_8 79..139 CDD:290566 22/59 (37%)
leucine-rich repeat 81..104 CDD:275380 9/22 (41%)
LRR_RI <96..304 CDD:238064 67/262 (26%)
LRR_4 104..143 CDD:289563 13/38 (34%)
leucine-rich repeat 105..128 CDD:275380 9/22 (41%)
LRR_8 127..187 CDD:290566 20/87 (23%)
leucine-rich repeat 129..152 CDD:275380 6/22 (27%)
leucine-rich repeat 153..176 CDD:275380 8/50 (16%)
LRR_8 177..235 CDD:290566 24/83 (29%)
leucine-rich repeat 177..200 CDD:275380 7/22 (32%)
leucine-rich repeat 201..224 CDD:275380 12/48 (25%)
LRR_8 225..284 CDD:290566 16/58 (28%)
leucine-rich repeat 225..248 CDD:275380 6/22 (27%)
leucine-rich repeat 250..273 CDD:275380 7/22 (32%)
LRRCT 304..351 CDD:214507 13/44 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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