DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and Lrt

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_001286640.1	Gene:	Lrt / 37342	FlyBaseID:	FBgn0034540	Length:	830	Species:	Drosophila melanogaster

Alignment Length:	421	Identity:	115/421 - (27%)
Similarity:	175/421 - (41%)	Gaps:	99/421 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 PNL---RQLNLS-GCGLVDIRGNHFAPESALQRIDFSHNQMELLDRDFFGNLRKLIYANFSHNAL 164
            ||:   |...|. ||.|         |.:....||. |..|.|.||     ||...|:    .:|
  Fly   133 PNITGTRNAELECGCDL---------PHTLRCNIDL-HGMMLLADR-----LRTSPYS----ISL 178

  Fly   165 KQCDLPHMPLLNRLELGHNRLVNATFGVCPQLQELILNDNQLIQLDVNAFRGLHGLLE-LQLSGN 228
            ..|.|.::..|:..::..|          ..|..|:::..::.::..:||.|:.|.|: |.|.||
  Fly   179 LDCSLRNVTFLSDAKIFDN----------VSLHGLVISSGEIKRVHKSAFLGIRGPLQALGLPGN 233

  Fly   229 RLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQLDLSGNRIRLLFDNQFRVL 293
            .|.|:                ..|||..|..            |::|||:.|:|:.|....|..|
  Fly   234 ALMSV----------------PWNALSTLSA------------LERLDLANNKIKALGTADFVGL 270

  Fly   294 ARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPA--TFAALLNLDTLDLSYNNLEF 356
            ..|..|::|.|.|:|:|...||.|..|..|.|..|.:.:...:  :.:..|:|..|||..|||..
  Fly   271 TSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRLGDYAQSLRSLSQCLSLRQLDLQANNLNG 335

  Fly   357 -LEEQIFGGNTLPRMRR---LNLNGNRMKHLHPLAFSSLPFLEYLKLGHNE-------------- 403
             |.||     |||.||.   ||||.|.:|.:...|.::...|..|.|.||:
  Fly   336 PLSEQ-----TLPGMRNLESLNLNRNLIKSIQNKALANFSRLVSLSLRHNQIDVLQDHAFFGLGA 395

  Fly   404 LKSLDV----------RMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKV 458
            |.|||:          .....:.||..|.|.||.|..:..|::..|.|::|:.:..|.::.:|:.
  Fly   396 LDSLDLSYNGIVAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDISIVARN 460

  Fly   459 NV-SFPNLKRVAIEGNPWQCPCFVK-LQHWL 487
            .: ....|:.:.::.||..|.|.:: ...||
  Fly   461 AMDGARELESLQMQENPLSCDCSIRPFAEWL 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	39/156 (25%)
		LRR_8	104..164	CDD:290566	18/63 (29%)
		leucine-rich repeat	106..129	CDD:275380	6/26 (23%)
		leucine-rich repeat	130..153	CDD:275380	8/22 (36%)
		leucine-rich repeat	154..195	CDD:275380	6/40 (15%)
		LRR_RI	194..455	CDD:238064	84/291 (29%)
		LRR_8	194..254	CDD:290566	14/60 (23%)
		leucine-rich repeat	196..219	CDD:275380	5/22 (23%)
		leucine-rich repeat	220..243	CDD:275380	7/23 (30%)
		leucine-rich repeat	244..267	CDD:275380	4/22 (18%)
		LRR_8	271..330	CDD:290566	23/58 (40%)
		leucine-rich repeat	272..295	CDD:275380	9/22 (41%)
		leucine-rich repeat	296..319	CDD:275380	10/22 (45%)
		LRR_8	319..380	CDD:290566	25/66 (38%)
		leucine-rich repeat	320..343	CDD:275380	4/24 (17%)
		leucine-rich repeat	344..369	CDD:275380	12/25 (48%)
		LRR_8	368..428	CDD:290566	25/86 (29%)
		leucine-rich repeat	370..393	CDD:275380	9/25 (36%)
		leucine-rich repeat	394..417	CDD:275380	9/46 (20%)
		leucine-rich repeat	418..441	CDD:275380	8/22 (36%)
Lrt	NP_001286640.1	LRR_RI	<151..334	CDD:238064	62/230 (27%)
		leucine-rich repeat	179..199	CDD:275378	4/29 (14%)
		leucine-rich repeat	200..223	CDD:275380	5/22 (23%)
		leucine-rich repeat	225..248	CDD:275380	11/38 (29%)
		LRR_8	249..307	CDD:290566	23/57 (40%)
		leucine-rich repeat	249..272	CDD:275380	9/22 (41%)
		LRR_RI	<270..479	CDD:238064	63/213 (30%)
		leucine-rich repeat	273..296	CDD:275380	10/22 (45%)
		leucine-rich repeat	297..322	CDD:275380	4/24 (17%)
		LRR_8	322..382	CDD:290566	27/64 (42%)
		leucine-rich repeat	323..347	CDD:275380	14/28 (50%)
		leucine-rich repeat	348..371	CDD:275380	7/22 (32%)
		LRR_8	370..428	CDD:290566	13/57 (23%)
		leucine-rich repeat	372..395	CDD:275380	5/22 (23%)
		leucine-rich repeat	396..419	CDD:275380	4/22 (18%)
		LRR_8	418..478	CDD:290566	15/59 (25%)
		leucine-rich repeat	420..443	CDD:275380	8/22 (36%)
		leucine-rich repeat	444..467	CDD:275380	3/22 (14%)
		LRRCT	476..526	CDD:214507	6/16 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910