DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and Lrg1

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:XP_038939951.1 Gene:Lrg1 / 367455 RGDID:1359464 Length:342 Species:Rattus norvegicus


Alignment Length:301 Identity:89/301 - (29%)
Similarity:128/301 - (42%) Gaps:56/301 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   204 NQLIQLDVNAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVF---GAV 265
            :.|.||...|.:|..||.||.||.|||..:......|:.:||.|:|::|||.:|.|.:|   .|:
  Rat    71 SSLTQLPAAALQGCPGLQELHLSSNRLQELSPGLLAPVPRLRVLDLTRNALRSLPPGLFRSSAAL 135

  Fly   266 QNFVLHLQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAI 330
            ...||...||..:..|       ..:.|..|..||::.|.:.||.......||:|.         
  Rat   136 NTLVLRENQLQEASAR-------WLQGLDALGYLDLAENRLRSLPARLLANLGALH--------- 184

  Fly   331 LEIKPATFAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPFLE 395
                           ||||.:|.||.|.|....|..  |::||:|.|||::.|.....:..|||.
  Rat   185 ---------------TLDLGHNLLESLPEGFLRGPR--RLQRLHLEGNRLQRLEAGLLAPQPFLG 232

  Fly   396 YLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKVNV 460
            .|.|..|:|.::....|..:::|..|.|.:|           ||||....|     ..||.:...
  Rat   233 VLFLNDNQLTAVAADSFRGLKQLDMLDLSNN-----------SLSSTPPGL-----WAFLGRPTR 281

  Fly   461 SFPNLKRVAIEGNPWQC-PCFVKLQHWL-ATRDVVYLRDNT 499
            ...:  ...:..|||.| ...|.|..|| |.|..::.:::|
  Rat   282 DMQD--GFDVSHNPWVCDKDLVDLCRWLAANRHKMFSQNDT 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 22/51 (43%)
LRR_8 104..164 CDD:290566
leucine-rich repeat 106..129 CDD:275380
leucine-rich repeat 130..153 CDD:275380
leucine-rich repeat 154..195 CDD:275380
LRR_RI 194..455 CDD:238064 76/253 (30%)
LRR_8 194..254 CDD:290566 20/49 (41%)
leucine-rich repeat 196..219 CDD:275380 5/14 (36%)
leucine-rich repeat 220..243 CDD:275380 9/22 (41%)
leucine-rich repeat 244..267 CDD:275380 11/25 (44%)
LRR_8 271..330 CDD:290566 13/58 (22%)
leucine-rich repeat 272..295 CDD:275380 4/22 (18%)
leucine-rich repeat 296..319 CDD:275380 7/22 (32%)
LRR_8 319..380 CDD:290566 17/60 (28%)
leucine-rich repeat 320..343 CDD:275380 1/22 (5%)
leucine-rich repeat 344..369 CDD:275380 10/24 (42%)
LRR_8 368..428 CDD:290566 20/59 (34%)
leucine-rich repeat 370..393 CDD:275380 7/22 (32%)
leucine-rich repeat 394..417 CDD:275380 6/22 (27%)
leucine-rich repeat 418..441 CDD:275380 6/22 (27%)
Lrg1XP_038939951.1 PRK15370 <55..>293 CDD:185268 78/272 (29%)
leucine-rich repeat 65..86 CDD:275380 5/14 (36%)
leucine-rich repeat 87..110 CDD:275380 9/22 (41%)
leucine-rich repeat 111..134 CDD:275380 10/22 (45%)
leucine-rich repeat 135..158 CDD:275380 6/29 (21%)
leucine-rich repeat 159..182 CDD:275380 7/22 (32%)
leucine-rich repeat 183..206 CDD:275380 11/48 (23%)
leucine-rich repeat 207..230 CDD:275380 7/22 (32%)
leucine-rich repeat 231..254 CDD:275380 6/22 (27%)
leucine-rich repeat 255..278 CDD:275380 11/38 (29%)
PCC 259..>339 CDD:188093 20/80 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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