DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and fliI

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_525097.1	Gene:	fliI / 33110	FlyBaseID:	FBgn0000709	Length:	1256	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	133/500 - (26%)
Similarity:	207/500 - (41%)	Gaps:	130/500 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 SILPNLRQLNLSGCGLVDIRGNHFA---PESALQRIDFSHNQMELLDR-------DFFGNLRKLI 155
            |:||.:|.        ||...|.|:   |.|..|   .|..|...|||       :..|:|:||.
  Fly     2 SVLPFVRG--------VDFTKNDFSATFPSSMRQ---MSRVQWLTLDRTQLAEIPEELGHLQKLE 55

  Fly   156 YANFSHNALKQC--DLPHMPLLNRLELGHNRLVNATFGVCPQ---LQELI---LNDNQLIQLDVN 212
            :.:.:||.|::.  :|..:..|..|:|.||:|.|:  |:.|:   |:||.   |:.|:|.::...
  Fly    56 HLSLNHNRLEKIFGELTELSCLRSLDLRHNQLKNS--GIPPELFHLEELTTLDLSHNKLKEVPEG 118

  Fly   213 AFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQLDL 277
            ..|. ..|:.|.||.|::.||....|..|..|..|:||.|.|:.|.|..     ..:::|:.|||
  Fly   119 LERA-KNLIVLNLSNNQIESIPTPLFIHLTDLLFLDLSHNRLETLPPQT-----RRLINLKTLDL 177

  Fly   278 SGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALL 342
            |.|.:.|.   |.|.|..||.|:|.:.|            |:.|.| |.:       |.:..:|.
  Fly   178 SHNPLELF---QLRQLPSLQSLEVLKMS------------GTQRTL-LNF-------PTSIDSLA 219

  Fly   343 NLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSL 407
            ||..||||:|:|..|.:.::...||.   ||||:.|.:..|                      :.
  Fly   220 NLCELDLSHNSLPKLPDCVYNVVTLV---RLNLSDNELTEL----------------------TA 259

  Fly   408 DVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTF---------LAKVNV--S 461
            .|.::   :||:.|:|..|.|..:.. .|..|..::.:||::|:|.|         |..:.|  :
  Fly   260 GVELW---QRLESLNLSRNQLVALPA-ALCKLPKLRRLLVNDNKLNFEGIPSGIGKLGALEVFSA 320

  Fly   462 FPNLKRVAIEGNPWQCPCFVKLQ---------------HWLATRDVVYLRDNTGYYKGERP---- 507
            ..||..:..||   .|.|....|               |.|...|.:.||:|.......:|
  Fly   321 ANNLLEMVPEG---LCRCGALKQLNLSCNRLITLPDAIHLLEGLDQLDLRNNPELVMPPKPSEAS 382

  Fly   508 ---LCIVTNVDYCIQNLQAVRRLGILGDFQGEQVEADAFDDDASA 549
               .....|:|:.:|.     :|.:.|......:.:.|...|::|
  Fly   383 KATSLEFYNIDFSLQT-----QLRLAGAAVPPSMPSSATPKDSTA 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	54/170 (32%)
		LRR_8	104..164	CDD:290566	20/69 (29%)
		leucine-rich repeat	106..129	CDD:275380	6/25 (24%)
		leucine-rich repeat	130..153	CDD:275380	8/29 (28%)
		leucine-rich repeat	154..195	CDD:275380	13/42 (31%)
		LRR_RI	194..455	CDD:238064	77/275 (28%)
		LRR_8	194..254	CDD:290566	22/65 (34%)
		leucine-rich repeat	196..219	CDD:275380	7/25 (28%)
		leucine-rich repeat	220..243	CDD:275380	9/22 (41%)
		leucine-rich repeat	244..267	CDD:275380	8/22 (36%)
		LRR_8	271..330	CDD:290566	19/58 (33%)
		leucine-rich repeat	272..295	CDD:275380	10/22 (45%)
		leucine-rich repeat	296..319	CDD:275380	5/22 (23%)
		LRR_8	319..380	CDD:290566	21/60 (35%)
		leucine-rich repeat	320..343	CDD:275380	5/22 (23%)
		leucine-rich repeat	344..369	CDD:275380	10/24 (42%)
		LRR_8	368..428	CDD:290566	12/59 (20%)
		leucine-rich repeat	370..393	CDD:275380	6/22 (27%)
		leucine-rich repeat	394..417	CDD:275380	1/22 (5%)
		leucine-rich repeat	418..441	CDD:275380	7/22 (32%)
fliI	NP_525097.1	leucine-rich repeat	7..30	CDD:275380	8/33 (24%)
		leucine-rich repeat	31..53	CDD:275380	6/21 (29%)
		LRR_8	53..112	CDD:290566	20/60 (33%)
		leucine-rich repeat	54..76	CDD:275380	5/21 (24%)
		LRR_RI	70..304	CDD:238064	86/293 (29%)
		leucine-rich repeat	77..101	CDD:275380	10/25 (40%)
		LRR_8	101..159	CDD:290566	20/58 (34%)
		leucine-rich repeat	102..124	CDD:275380	5/22 (23%)
		leucine-rich repeat	125..148	CDD:275380	9/22 (41%)
		leucine-rich repeat	149..171	CDD:275380	8/26 (31%)
		LRR_8	152..231	CDD:290566	35/106 (33%)
		leucine-rich repeat	172..195	CDD:275380	11/25 (44%)
		leucine-rich repeat	196..220	CDD:275380	9/43 (21%)
		leucine-rich repeat	221..243	CDD:275380	8/21 (38%)
		LRR_8	243..300	CDD:290566	20/85 (24%)
		leucine-rich repeat	244..266	CDD:275380	8/49 (16%)
		leucine-rich repeat	267..289	CDD:275380	7/22 (32%)
		leucine-rich repeat	290..314	CDD:275380	6/23 (26%)
		LRR_8	315..370	CDD:290566	13/57 (23%)
		leucine-rich repeat	315..335	CDD:275380	6/22 (27%)
		leucine-rich repeat	338..360	CDD:275378	3/21 (14%)
		gelsolin_S1_like	491..602	CDD:200446
		gelsolin_like	618..706	CDD:200436
		gelsolin_S3_like	729..828	CDD:200448
		gelsolin_like	920..1015	CDD:200436
		gelsolin_S5_like	1037..1141	CDD:200444
		gelsolin_S6_like	1151..1250	CDD:200447
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910