Protein Alignment CG6749 and Slitrk1

DIOPT Version :9

• Sequence 1: NP_648354.1
• Gene: CG6749 / 39144
• FlyBaseID: FBgn0036040
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_001100753.1
• Gene: Slitrk1 / 306147
• RGDID: 1308858
• Length: 696
• Species: Rattus norvegicus
• Alignment Length: 629
• Identity: 138/629 - (21%)
• Similarity: 240/629 - (38%)
• Gaps: 169/629 - (26%)

  Fly    11 LLLWLLCMGFPILHGA-----DLCQPIGWRNFQCSEVASLQDL-VDLGAENWHTLAIRNVQTELE 69
            :|||:|.:...:...|     |:|:.   :...|:|:..  || ||...:.:.:|......|
  Rat     1 MLLWILLLETSLCFAAGNVTGDVCKE---KICSCNEIEG--DLHVDCEKKGFTSLQRFTAPT--- 57

  Fly    70 VGSGENADHLANLLDLDLTGAAPINVHTNGFSILPNLRQLNLSGCGLVDIRGNHFAPESALQRID 134
                      :....|.|.|.:...:..|.|:...|...|::...||.:|....|.....::|:.
  Rat    58 ----------SQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLH 112

  Fly   135 FSHNQMELLDRDFFGNLRKLIYANFSHNALKQCDLPHMPLLNRLELGHNRLVNATFGVCPQLQEL 199
            .::|:::...:..|..|..|.|.....|.|:..|......||:||:                  |
  Rat   113 INNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEV------------------L 159

  Fly   200 ILNDNQLIQLDVNAFRGLHGLLELQLSGNRLSSIGL-ETFQPLAQLRKLNLSQNALD------AL 257
            |||||.:..|..|.|:.: .:..|.|.||||.::.. |..:.:..:.::.|..|..|      :|
  Rat   160 ILNDNLISTLPANVFQYV-PITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSL 223

  Fly   258 RPNVFGAVQNFVL---------HLQQLDLS----------GNRI--------------------- 282
            :..:....:|.::         .||..||:          .||:
  Rat   224 KEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPT 288

  Fly   283 ---------------------RLLFDNQFRV---------LAR---------------------- 295
                                 ::..:.|.::         .||
  Rat   289 PFKINGQDEHATPGAVPNGGTKIPGNWQLKIKPTPPIATGSARNKPPVHGLPCPGGCSCDHIPGS 353

  Fly   296 -LQMLDVSRN--SIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDLSYNNLEFL 357
             |:|...:||  |:|.|.|.    |.::::|:|:.|.|..|:.:.|....||..|||..||:..:
  Rat   354 GLKMNCNNRNVSSLADLKPK----LSNVQELFLRDNKIHSIRRSHFVDYKNLILLDLGNNNIANI 414

  Fly   358 EEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSLDVRMFAPMRRLQKLH 422
            |...|  ..|..:|.|.::.|.:..|....|:.|..||||.:.:|.::.:....|..|.:|:.|.
  Rat   415 ENNTF--KNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILI 477

  Fly   423 LGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKVNV--SFPNLKRVAIEGNPWQCPC-FVKLQ 484
            |.:|||..:.:||...: |:.::.:.||...:|....|  ...::.::.:.||||:|.| .|..:
  Rat   478 LNNNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFK 541

  Fly   485 HWLATR--DVVYLRDNTGYYKGERPL-------CIVTNVDYCIQ 519
            .| |.|  ..|.:.|    .|.|.|:       .:::|.:.|.|
  Rat   542 QW-AERLGSEVLMSD----LKCETPVNFFRKDFMLLSNDEICPQ 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	38/159 (24%)
		LRR_8	104..164	CDD:290566	13/59 (22%)
		leucine-rich repeat	106..129	CDD:275380	5/22 (23%)
		leucine-rich repeat	130..153	CDD:275380	4/22 (18%)
		leucine-rich repeat	154..195	CDD:275380	9/40 (23%)
		LRR_RI	194..455	CDD:238064	79/362 (22%)
		LRR_8	194..254	CDD:290566	18/60 (30%)
		leucine-rich repeat	196..219	CDD:275380	9/22 (41%)
		leucine-rich repeat	220..243	CDD:275380	7/23 (30%)
		leucine-rich repeat	244..267	CDD:275380	4/28 (14%)
		LRR_8	271..330	CDD:290566	21/144 (15%)
		leucine-rich repeat	272..295	CDD:275380	7/83 (8%)
		leucine-rich repeat	296..319	CDD:275380	9/24 (38%)
		LRR_8	319..380	CDD:290566	19/60 (32%)
		leucine-rich repeat	320..343	CDD:275380	6/22 (27%)
		leucine-rich repeat	344..369	CDD:275380	9/24 (38%)
		LRR_8	368..428	CDD:290566	17/59 (29%)
		leucine-rich repeat	370..393	CDD:275380	6/22 (27%)
		leucine-rich repeat	394..417	CDD:275380	7/22 (32%)
		leucine-rich repeat	418..441	CDD:275380	8/22 (36%)
Slitrk1	NP_001100753.1	leucine-rich repeat	39..60	CDD:275380	4/33 (12%)
		leucine-rich repeat	62..83	CDD:275380	5/20 (25%)
		leucine-rich repeat	84..107	CDD:275380	5/22 (23%)
		LRR_8	108..166	CDD:290566	19/75 (25%)
		leucine-rich repeat	108..131	CDD:275380	4/22 (18%)
		leucine-rich repeat	132..155	CDD:275380	6/22 (27%)
		LRR_8	155..213	CDD:290566	19/76 (25%)
		leucine-rich repeat	156..177	CDD:275380	11/38 (29%)
		TPKR_C2	212..>250	CDD:301599	6/37 (16%)
		leucine-rich repeat	356..372	CDD:275380	6/15 (40%)
		leucine-rich repeat	377..400	CDD:275380	6/22 (27%)
		leucine-rich repeat	401..424	CDD:275380	9/24 (38%)
		LRR_8	425..483	CDD:290566	17/57 (30%)
		leucine-rich repeat	425..448	CDD:275380	6/22 (27%)
		leucine-rich repeat	449..472	CDD:275380	7/22 (32%)
		LRR_8	471..530	CDD:290566	14/59 (24%)
		leucine-rich repeat	473..495	CDD:275380	8/22 (36%)
		leucine-rich repeat	496..520	CDD:275380	4/23 (17%)
		TPKR_C2	529..579	CDD:301599	15/54 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910