DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and Rxfp1

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	XP_006232570.1	Gene:	Rxfp1 / 295144	RGDID:	1302973	Length:	763	Species:	Rattus norvegicus

Alignment Length:	405	Identity:	99/405 - (24%)
Similarity:	167/405 - (41%)	Gaps:	88/405 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 DLTGAAPINVHTNGFSILPNLRQLNLSGCGLVDIRGNHFAPESALQRIDFSHNQMEL-LDRDFFG 149
            :::...|..:|.||.....|  |.:...||                    .:|...| ||: :|.
  Rat    42 NISKCLPQLLHCNGVDDCGN--QADEDNCG--------------------DNNGWSLQLDK-YFA 83

  Fly   150 NLRKLIYANFSHNALKQCDLPHMP---LLNRLELGHNRL-VNATFGVCPQLQELILNDNQLIQLD 210
            |..||...|.......:|.:..:|   |...|||..:.. :.|...|...:..:.|..|.:..|.
  Rat    84 NYYKLTSTNSIEAETSECLVGSVPMHCLCRDLELDCDEANLRAVPSVSSNVTVMSLQWNFIRTLP 148

  Fly   211 VNAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQL 275
            .|:||..|.|.:|.|..|::.|:.:..|:.|..|.||.||.|.:..|:|.|
  Rat   149 PNSFRMYHDLQKLCLQNNKIRSVSVSAFRGLHSLTKLYLSHNRITFLKPGV-------------- 199

  Fly   276 DLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEI--KPATF 338
                          |..|.||:.|.:..|.::.:||..|.||.||..|.|..||:..:  ||
  Rat   200 --------------FEDLHRLEWLIIEDNHLSRISPLTFYGLNSLILLVLMNNALTRLPDKP--- 247

  Fly   339 AALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLN-----------LNGNRMKHLHPLAFSSLP 392
                    |......|.:|:   |.||.:..:|.|.           :..|::.||:..||:.|.
  Rat   248 --------LCQHMPRLHWLD---FEGNRIHNLRNLTFISCNNLTVLVMRKNKINHLNEHAFTHLQ 301

  Fly   393 FLEYLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEIL----VDN-NRL 452
            .|:.|.||.|::::|...:|..::.|.:|::.:|.:::|.::..:.|:.::.:|    :.| .:.
  Rat   302 KLDELDLGSNKIENLPPNIFKDLKELSQLNISYNPIQKIEVNQFDYLAKLKSLLEGIEISNIQQR 366

  Fly   453 TFLAKVNVSFPNLKR 467
            .|...:|:|....|:
  Rat   367 MFRPLINLSHIYFKK 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	41/157 (26%)
		LRR_8	104..164	CDD:290566	13/60 (22%)
		leucine-rich repeat	106..129	CDD:275380	3/22 (14%)
		leucine-rich repeat	130..153	CDD:275380	6/23 (26%)
		leucine-rich repeat	154..195	CDD:275380	10/44 (23%)
		LRR_RI	194..455	CDD:238064	70/278 (25%)
		LRR_8	194..254	CDD:290566	20/59 (34%)
		leucine-rich repeat	196..219	CDD:275380	6/22 (27%)
		leucine-rich repeat	220..243	CDD:275380	7/22 (32%)
		leucine-rich repeat	244..267	CDD:275380	9/22 (41%)
		LRR_8	271..330	CDD:290566	16/58 (28%)
		leucine-rich repeat	272..295	CDD:275380	2/22 (9%)
		leucine-rich repeat	296..319	CDD:275380	8/22 (36%)
		LRR_8	319..380	CDD:290566	17/73 (23%)
		leucine-rich repeat	320..343	CDD:275380	7/24 (29%)
		leucine-rich repeat	344..369	CDD:275380	6/24 (25%)
		LRR_8	368..428	CDD:290566	18/70 (26%)
		leucine-rich repeat	370..393	CDD:275380	8/33 (24%)
		leucine-rich repeat	394..417	CDD:275380	7/22 (32%)
		leucine-rich repeat	418..441	CDD:275380	5/22 (23%)
Rxfp1	XP_006232570.1	LDLa	33..68	CDD:238060	6/27 (22%)
		leucine-rich repeat	134..157	CDD:275380	6/22 (27%)
		LRR_RI	138..356	CDD:238064	68/259 (26%)
		LRR_8	158..216	CDD:290566	22/85 (26%)
		leucine-rich repeat	158..181	CDD:275380	7/22 (32%)
		leucine-rich repeat	182..205	CDD:275380	11/50 (22%)
		LRR_8	205..265	CDD:290566	23/73 (32%)
		leucine-rich repeat	206..229	CDD:275380	8/22 (36%)
		leucine-rich repeat	230..254	CDD:275380	8/34 (24%)
		leucine-rich repeat	255..278	CDD:275380	7/25 (28%)
		LRR_8	278..337	CDD:290566	16/58 (28%)
		leucine-rich repeat	279..302	CDD:275380	6/22 (27%)
		leucine-rich repeat	303..326	CDD:275380	7/22 (32%)
		leucine-rich repeat	327..350	CDD:275380	5/22 (23%)
		leucine-rich repeat	351..371	CDD:275380	3/19 (16%)
		7tm_1	427..686	CDD:278431
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910