DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and Lrrc66

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:NP_705796.1 Gene:Lrrc66 / 231296 MGIID:2387634 Length:872 Species:Mus musculus


Alignment Length:200 Identity:51/200 - (25%)
Similarity:80/200 - (40%) Gaps:42/200 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   123 HFAPESALQRIDFSHNQMELLDRDFFGNLRKLIYANFSHNALK--QCDLPHMPLLNRLELG---H 182
            |...|..::..|.:|:::..:..|...:|..|...|.|:.|:.  ..|.|..|..::...|   |
Mouse    73 HTQKERHIKPPDRTHHRISKVTLDPLAHLHALEILNLSNKAIHYFSLDQPLPPSSHQKRHGGHSH 137

  Fly   183 NRLVNATFGVCPQLQELILNDNQLIQLDVNAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKL 247
            :||        |:||.|||..|||.......:: |..|..|.||.||:..|||..|....||..:
Mouse   138 SRL--------PRLQVLILQRNQLSGTPKGLWK-LKSLRSLDLSFNRIVHIGLSDFHGCLQLESI 193

  Fly   248 NLSQNALDALRPNVFGAVQNFVLHLQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPA 312
            .|..|.:..:.|..                            |:.|.:||::|:..|::.:|.|.
Mouse   194 YLKSNKICTIHPKA----------------------------FKGLKKLQVVDLRSNALTTLVPI 230

  Fly   313 HFVGL 317
            ..:.|
Mouse   231 VTIAL 235

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 41/137 (30%)
LRR_8 104..164 CDD:290566 9/40 (23%)
leucine-rich repeat 106..129 CDD:275380 2/5 (40%)
leucine-rich repeat 130..153 CDD:275380 4/22 (18%)
leucine-rich repeat 154..195 CDD:275380 11/45 (24%)
LRR_RI 194..455 CDD:238064 33/123 (27%)
LRR_8 194..254 CDD:290566 24/59 (41%)
leucine-rich repeat 196..219 CDD:275380 9/22 (41%)
leucine-rich repeat 220..243 CDD:275380 10/22 (45%)
leucine-rich repeat 244..267 CDD:275380 4/22 (18%)
LRR_8 271..330 CDD:290566 8/46 (17%)
leucine-rich repeat 272..295 CDD:275380 2/22 (9%)
leucine-rich repeat 296..319 CDD:275380 6/21 (29%)
LRR_8 319..380 CDD:290566
leucine-rich repeat 320..343 CDD:275380
leucine-rich repeat 344..369 CDD:275380
LRR_8 368..428 CDD:290566
leucine-rich repeat 370..393 CDD:275380
leucine-rich repeat 394..417 CDD:275380
leucine-rich repeat 418..441 CDD:275380
Lrrc66NP_705796.1 LRR <95..326 CDD:227223 46/177 (26%)
leucine-rich repeat 104..142 CDD:275380 11/45 (24%)
LRR 1 142..164 8/22 (36%)
leucine-rich repeat 143..165 CDD:275380 9/22 (41%)
LRR_8 165..224 CDD:338972 21/86 (24%)
LRR 2 165..186 10/20 (50%)
leucine-rich repeat 166..189 CDD:275380 10/22 (45%)
LRR 3 189..210 6/48 (13%)
leucine-rich repeat 190..213 CDD:275380 6/50 (12%)
LRR 4 213..234 6/20 (30%)
LRR 5 239..259
leucine-rich repeat 240..263 CDD:275380
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 339..363
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 467..501
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 560..579
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 695..761
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 776..872
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45617
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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