DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and Lrrtm3

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:NP_848793.1 Gene:Lrrtm3 / 216028 MGIID:2389177 Length:582 Species:Mus musculus


Alignment Length:351 Identity:102/351 - (29%)
Similarity:162/351 - (46%) Gaps:50/351 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   199 LILNDNQLIQLDVNAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFG 263
            |.|..|.|.:|..|.|:||:.|..|.|..|.:|                |:.:||.:.:|     
Mouse    66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHIS----------------NIDENAFNGIR----- 109

  Fly   264 AVQNFVLHLQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYN 328
                   .|::|.||.|||....:|.||.:..|:.||:|.|.:.||....|.||..|..|:|:.|
Mouse   110 -------RLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSN 167

  Fly   329 AILEIKPATFAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPF 393
            ::..|....|....||:.|||.||.:..|...:|.|  :.|::.|:|..|:...|:...|..|..
Mouse   168 SLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAG--MIRLKELHLEHNQFSKLNLALFPRLVS 230

  Fly   394 LEYLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEIN-LDVLESLSSVQEILVDNNRLTFLA- 456
            |:.|.:..|::..:...|......||:|.|..|.:|..: ..|.:.:.::|.:.:|:|:|||:. 
Mouse   231 LQNLYMQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQ 295

  Fly   457 KVNVSFPNLKRVAIEGNPWQCP---CFVKLQHWLATRDVVYLRDNTGYYKGERPLCIVTNVDYCI 518
            ::..|:.:|..:::.||.|:|.   |  .|.:||  |....||:||......:.|..|..:|   
Mouse   296 EILDSWISLNDISLAGNIWECSRNIC--SLVNWL--RSFKGLRENTIICASPKELQGVNVID--- 353

  Fly   519 QNLQAVRRLGILGDFQGEQVEADAFD 544
                ||:...|.    |:....:.||
Mouse   354 ----AVKNYSIC----GKSTTTERFD 371

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 17/56 (30%)
LRR_8 104..164 CDD:290566
leucine-rich repeat 106..129 CDD:275380
leucine-rich repeat 130..153 CDD:275380
leucine-rich repeat 154..195 CDD:275380
LRR_RI 194..455 CDD:238064 77/256 (30%)
LRR_8 194..254 CDD:290566 16/54 (30%)
leucine-rich repeat 196..219 CDD:275380 9/19 (47%)
leucine-rich repeat 220..243 CDD:275380 5/22 (23%)
leucine-rich repeat 244..267 CDD:275380 4/22 (18%)
LRR_8 271..330 CDD:290566 24/58 (41%)
leucine-rich repeat 272..295 CDD:275380 10/22 (45%)
leucine-rich repeat 296..319 CDD:275380 10/22 (45%)
LRR_8 319..380 CDD:290566 20/60 (33%)
leucine-rich repeat 320..343 CDD:275380 6/22 (27%)
leucine-rich repeat 344..369 CDD:275380 9/24 (38%)
LRR_8 368..428 CDD:290566 16/59 (27%)
leucine-rich repeat 370..393 CDD:275380 6/22 (27%)
leucine-rich repeat 394..417 CDD:275380 4/22 (18%)
leucine-rich repeat 418..441 CDD:275380 7/23 (30%)
Lrrtm3NP_848793.1 LRRNT 33..61 CDD:214470
LRR 1 63..83 7/16 (44%)
leucine-rich repeat 66..86 CDD:275380 9/19 (47%)
LRR_RI <81..300 CDD:238064 72/248 (29%)
LRR_8 86..145 CDD:290566 24/86 (28%)
LRR 2 86..107 8/36 (22%)
leucine-rich repeat 87..110 CDD:275380 9/50 (18%)
LRR 3 110..131 9/20 (45%)
leucine-rich repeat 111..134 CDD:275380 10/22 (45%)
LRR_8 133..193 CDD:290566 23/59 (39%)
LRR 4 134..155 8/20 (40%)
leucine-rich repeat 135..158 CDD:275380 10/22 (45%)
LRR 5 158..179 6/20 (30%)
leucine-rich repeat 159..182 CDD:275380 6/22 (27%)
LRR_8 181..241 CDD:290566 20/61 (33%)
LRR 6 182..203 9/20 (45%)
leucine-rich repeat 183..206 CDD:275380 9/24 (38%)
LRR 7 206..226 5/19 (26%)
leucine-rich repeat 207..230 CDD:275380 6/22 (27%)
LRR_8 230..290 CDD:290566 14/59 (24%)
LRR 8 230..251 4/20 (20%)
leucine-rich repeat 231..254 CDD:275380 4/22 (18%)
LRR 9 254..275 7/20 (35%)
leucine-rich repeat 255..279 CDD:275380 7/23 (30%)
LRR 10 279..300 6/20 (30%)
leucine-rich repeat 280..300 CDD:275380 6/19 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 378..410
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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