DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and lron-11

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:NP_491035.1 Gene:lron-11 / 171837 WormBaseID:WBGene00022129 Length:542 Species:Caenorhabditis elegans


Alignment Length:357 Identity:98/357 - (27%)
Similarity:168/357 - (47%) Gaps:36/357 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   165 KQCDLPHMPLL-----NRLELGHNRLVNAT---FGVCPQLQELILNDNQLIQLDVNAFRGLHGLL 221
            |...|..:|:|     ..|:|.:||:...:   ..:.|.|::|||::|.:..|..:.|..|..|.
 Worm    33 KGSSLRSIPILLDPRTTVLDLSNNRISRLSADELSLYPNLEQLILHNNSITHLSADVFSTLPSLR 97

  Fly   222 ELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQLDLSGNRIRLLF 286
            .|.||.|.|.|:..|.|..|..|:.|.:|.|.:. |.|..|..:.    .||.|.::.||:..|.
 Worm    98 VLDLSSNSLLSLPNEVFSKLKNLKTLIISSNDVQ-LGPECFAGLS----QLQTLSIADNRLSFLP 157

  Fly   287 DNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDLSY 351
            .:..:.|:.|:.||:|.|.:.|:..:....||.|..|.|:.|.:..::...|.:...|..||:|.
 Worm   158 PSVLKPLSGLRNLDLSANKLLSMPASVMNNLGGLETLKLKQNLLSSLETGMFLSQKELKHLDVSE 222

  Fly   352 NNLEFLEE-QIFG------------------GNT--LPRMRRLNLNGNRMKHLHPLAFSSLPFLE 395
            |.:..:|| .::|                  |||  ||.::.|:|:.|....|...:|..||.|:
 Worm   223 NLIGDIEEGALYGLEKLETLNLTNNQLVRLPGNTWSLPALKTLDLSSNLFVSLETASFDGLPALQ 287

  Fly   396 YLKLGHN-ELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKVN 459
            ||.:.|: .||::.:..|..:..|..|.:..:.|..|:......:..:..:.:.||.|.::|...
 Worm   288 YLNISHSRNLKTIQMATFVQLSSLHWLSISSSALTHIHPSAFNPIPPLSHLDLSNNELRYVAPGM 352

  Fly   460 VSFPNLKRVAIEGNPWQCPCFVKLQHWLATRD 491
            :.:||::.:.:..|.|.|.|.:::.: |..||
 Worm   353 LQWPNIRNLHLANNDWHCSCDLRVSN-LNPRD 383

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 31/98 (32%)
LRR_8 104..164 CDD:290566
leucine-rich repeat 106..129 CDD:275380
leucine-rich repeat 130..153 CDD:275380
leucine-rich repeat 154..195 CDD:275380 8/37 (22%)
LRR_RI 194..455 CDD:238064 80/282 (28%)
LRR_8 194..254 CDD:290566 23/59 (39%)
leucine-rich repeat 196..219 CDD:275380 8/22 (36%)
leucine-rich repeat 220..243 CDD:275380 10/22 (45%)
leucine-rich repeat 244..267 CDD:275380 7/22 (32%)
LRR_8 271..330 CDD:290566 19/58 (33%)
leucine-rich repeat 272..295 CDD:275380 7/22 (32%)
leucine-rich repeat 296..319 CDD:275380 7/22 (32%)
LRR_8 319..380 CDD:290566 21/81 (26%)
leucine-rich repeat 320..343 CDD:275380 5/22 (23%)
leucine-rich repeat 344..369 CDD:275380 12/45 (27%)
LRR_8 368..428 CDD:290566 17/60 (28%)
leucine-rich repeat 370..393 CDD:275380 6/22 (27%)
leucine-rich repeat 394..417 CDD:275380 7/23 (30%)
leucine-rich repeat 418..441 CDD:275380 4/22 (18%)
lron-11NP_491035.1 leucine-rich repeat 48..71 CDD:275380 4/22 (18%)
LRR_RI <50..177 CDD:238064 42/131 (32%)
LRR_8 70..130 CDD:290566 23/59 (39%)
leucine-rich repeat 72..95 CDD:275380 8/22 (36%)
leucine-rich repeat 96..119 CDD:275380 10/22 (45%)
LRR_8 118..177 CDD:290566 19/63 (30%)
leucine-rich repeat 120..142 CDD:275380 7/26 (27%)
LRR_RI <141..270 CDD:238064 35/132 (27%)
leucine-rich repeat 143..166 CDD:275380 7/22 (32%)
leucine-rich repeat 167..190 CDD:275380 7/22 (32%)
LRR_8 190..249 CDD:290566 13/58 (22%)
leucine-rich repeat 191..214 CDD:275380 5/22 (23%)
leucine-rich repeat 215..238 CDD:275380 8/22 (36%)
LRR_8 238..295 CDD:290566 16/56 (29%)
leucine-rich repeat 239..261 CDD:275380 4/21 (19%)
leucine-rich repeat 262..283 CDD:275380 5/20 (25%)
LRR_8 284..345 CDD:290566 14/60 (23%)
leucine-rich repeat 286..310 CDD:275380 7/23 (30%)
leucine-rich repeat 311..334 CDD:275380 4/22 (18%)
leucine-rich repeat 335..357 CDD:275380 4/21 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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