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Protein Alignment CG6749 and tol-1

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_001020983.1	Gene:	tol-1 / 171635	WormBaseID:	WBGene00006593	Length:	1221	Species:	Caenorhabditis elegans

Alignment Length:	520	Identity:	127/520 - (24%)
Similarity:	214/520 - (41%)	Gaps:	100/520 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 EVASLQDL----VDLGAENWHTLAIRNVQTELEVGSGENADHLANLLDLDLTGAAPINVHTNGFS 101
            |.:||..|    :||.         .|..||:....|:    :..|..:||:......|:....:
Worm   394 EPSSLSGLKLESLDLS---------HNKLTEVPAAIGK----VEQLKKVDLSHNRIAKVYQYVLN 445

  Fly   102 ILPNLRQLNLSGCGLVDIRGNHFAPESALQRIDFSHNQMELLDRDFFGNLRKLIYANFSHNALKQ 166
            .:..|..::||...|..|....|:..|.|..:|.|:|::.||.:|.|....||...:...|.:|.
Worm   446 KIKQLHTVDLSNNQLQSIGPYIFSDSSELHSLDVSNNEISLLFKDAFARCPKLRKISMKMNKIKS 510

  Fly   167 CD--LPHMPLLNRLELGHNRLVNATFGVCPQLQELILNDNQLIQL-------------------- 209
            .|  |.....|.||::.||.::...:...|:..|::..||..|.|
Worm   511 LDEGLTEASGLRRLDVSHNEILVLKWSALPENLEILNADNNDINLLTAASMSPSTANLKSVSLSN 575

  Fly   210 ----DVNAFRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVL 270
                .:||.:..:.|..|.:|.|||:.:|.......:|||:|||..|.|..:.......|:  .:
Worm   576 NGITIMNADQIPNSLESLDVSNNRLAKLGKTALAAKSQLRRLNLKGNLLTVVATESMKVVE--AV 638

  Fly   271 HLQQLDLSGNRIRLLFDNQFRVL---ARLQMLDVSRNSIASLSPA---HFVGLGSLRK--LYLQY 327
            |..::::|.|  .|:.|.|...:   |:.::| :..:..||.|.|   |.:.:.||.|  |...|
Worm   639 HPLKVEISEN--PLICDCQMGWMIGGAKPKVL-IQDSETASCSHAVDGHQIQIQSLSKKDLLCPY 700

  Fly   328 NAILE---------------IKPATFAAL----LNLDTLDLSYNN-----LEFL--------EEQ 360
            .::.|               :.||.....    .|::.:....|:     .||:        .|.
Worm   701 KSVCEPECICCQYGNCDCKSVCPANCRCFRDDQFNINIVRCHGNSSMVPKREFVVSELPVSATEI 765

  Fly   361 IFGGNTLP-----------RMRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSLDVRMFAP 414
            |..|.|||           |::||::||..::.:.|.||.:||.|:.|.|..|.|.||....|..
Worm   766 ILSGVTLPQLRTHSFIGRLRLQRLHINGTGLRSIQPKAFHTLPALKTLDLSDNSLISLSGEEFLK 830

  Fly   415 MRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKVNVSFPNLKRVAIEGNPWQCPC 479
            ...:.:|.|..|....::..:.|.|.:::.:.:.||.|..:.:| :....|.::::..||.:|.|
Worm   831 CGEVSQLFLNGNRFSTLSRGIFEKLPNLKYLTLHNNSLEDIPQV-LHSTALSKISLSSNPLRCDC 894

Fly 480 479
Worm 895 894

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.