Protein Alignment CG6749 and LOC1275449

DIOPT Version :10

• Sequence 1: NP_648354.1
• Gene: CG6749 / 39144
• FlyBaseID: FBgn0036040
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: XP_314696.5
• Gene: LOC1275449 / 1275449
• VectorBaseID: AGAMI1_005046
• Length: 618
• Species: Anopheles gambiae
• Alignment Length: 505
• Identity: 131/505 - (25%)
• Similarity: 207/505 - (40%)
• Gaps: 102/505 - (20%)

  Fly    52 GAENW---HTLAIRNVQTELEVGSGENADHLANLLDLDLTGAAPINVHTNGFSILPNLRQLNLSG 113
            |...|   .||.:..:...:...:||     ||.|..   |||.|.:.....::       :|:.
Mosquito     9 GCHCWALVRTLLLSTLLAVVLWPAGE-----ANALPY---GAADIELDEANDAV-------SLTA 58

  Fly   114 CGLVDIRGNHFAPESALQRIDFSHNQMELLDRDF---FGNLRKLIYANFSHNALKQCDLPHMPLL 175
            |.:.|:|......::.|. |..:|..::.|....   |.:|:.|...:...|.|:...|..:..:
Mosquito    59 CYVEDLRNIREHSQNPLV-IQINHCYLQELPNAIFIRFTDLQVLEICDSRVNNLQDFALNGLRNI 122

  Fly   176 NRLELGHNRLVNA---TFGVCPQLQELILNDNQLIQLDVNAFRGLHGLLELQLSGNRLSSIGLET 237
            ..|.|..|.|...   :......||.|.|..|.:..:|..:|:...||::|.|:.|.:::|...|
Mosquito   123 ESLNLSRNNLTTIKSWSDHDLDTLQVLDLRRNLIRSIDELSFQRYPGLVKLSLAVNFITTIPDGT 187

  Fly   238 FQPLAQLRKLNLSQNALD----------------ALRPNVFGAVQNFVL----HLQQLDLSGNRI 282
            |:|:|.|:.|||.:|.|.                |...|....:..|..    ||:.|.|.||::
Mosquito   188 FKPVANLKNLNLGKNLLTTIEEGTLRGLNKLTHVAFHHNRIRTIHPFAFVGNGHLKVLQLQGNQL 252

  Fly   283 RLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTL 347
            .....:.|..|.||..|:||.|.:.::....|...|.||.|.|.||.|..::..:|..|.:|:.|
Mosquito   253 GSFEPDLFGNLPRLTFLNVSSNELETVGNLSFKNSGDLRVLDLSYNRIGLLEDNSFKGLYDLEAL 317

  Fly   348 DLSYNNLEFLEEQI-----------FGGNTL-----------PRMRRLNLNGNRMKHLHPLAFSS 390
            ::|:|.|..:.:.:           ..||.|           ||:.||||:.|.:..:....|..
Mosquito   318 NVSHNQLATVSKYVLKDCANLRDLDLSGNRLDYVGLKLSSATPRLVRLNLSRNAIGEIERDVFED 382

  Fly   391 LPFLEYLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFL 455
            ||.|..|.|.||:|.. |..:::.| .|..|::..|...:||..:||||:..:  |.|
Mosquito   383 LPKLHTLDLAHNQLTD-DAFLWSLM-NLSVLNMSQNGFRKINASLLESLTLAE--LYD------- 436

  Fly   456 AKVNVSFPNLKRVAIEGNPWQCPCFV-KLQHWLATRDVV----YLRDNTG 500
                             |||.|...| :|.|  .:..|:    ||.::||
Mosquito   437 -----------------NPWDCRFLVQELAH--HSSSVIYGKNYLVEDTG 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_8	104..164	CDD:404697	12/62 (19%)
		leucine-rich repeat	106..129	CDD:275380	4/22 (18%)
		leucine-rich repeat	130..153	CDD:275380	6/25 (24%)
		leucine-rich repeat	154..195	CDD:275380	8/43 (19%)
		leucine-rich repeat	196..219	CDD:275380	7/22 (32%)
		LRR	199..>452	CDD:443914	86/294 (29%)
		leucine-rich repeat	220..243	CDD:275380	8/22 (36%)
		leucine-rich repeat	244..267	CDD:275380	8/38 (21%)
		leucine-rich repeat	272..295	CDD:275380	7/22 (32%)
		leucine-rich repeat	296..319	CDD:275380	6/22 (27%)
		leucine-rich repeat	320..343	CDD:275380	9/22 (41%)
		leucine-rich repeat	344..369	CDD:275380	8/46 (17%)
		leucine-rich repeat	370..393	CDD:275380	7/22 (32%)
		leucine-rich repeat	394..417	CDD:275380	8/22 (36%)
		leucine-rich repeat	418..441	CDD:275380	9/22 (41%)
LOC1275449	XP_314696.5	None