DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and LRRC39

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:NP_001243314.1 Gene:LRRC39 / 127495 HGNCID:28228 Length:339 Species:Homo sapiens


Alignment Length:236 Identity:64/236 - (27%)
Similarity:98/236 - (41%) Gaps:40/236 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   241 LAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRNS 305
            |.||::..|.:..|..: |...|..||.::    ||||.|.|..: .....:|.|||.|.:|.|.
Human    82 LNQLQEWQLHRTGLLKI-PEFIGRFQNLIV----LDLSRNTISEI-PPGIGLLTRLQELILSYNK 140

  Fly   306 IASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRM 370
            |.:: |.......||.||.|..|..:...|...:.||.|..||||.|:...:             
Human   141 IKTV-PKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTTI------------- 191

  Fly   371 RRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINL-- 433
                          |||..::|.||:|.:|.|:|:.|.    ..:.|:|.||.......||..  
Human   192 --------------PLAVLNMPALEWLDMGSNKLEQLP----DTIERMQNLHTLWLQRNEITCLP 238

  Fly   434 DVLESLSSVQEILVDNNRLTFLAKVNVSFPNLKRVAIEGNP 474
            ..:.::.::..:::.||:|..:........||:.|....||
Human   239 QTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNP 279

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 5/14 (36%)
LRR_8 104..164 CDD:290566
leucine-rich repeat 106..129 CDD:275380
leucine-rich repeat 130..153 CDD:275380
leucine-rich repeat 154..195 CDD:275380
LRR_RI 194..455 CDD:238064 59/215 (27%)
LRR_8 194..254 CDD:290566 4/12 (33%)
leucine-rich repeat 196..219 CDD:275380
leucine-rich repeat 220..243 CDD:275380 1/1 (100%)
leucine-rich repeat 244..267 CDD:275380 5/22 (23%)
LRR_8 271..330 CDD:290566 21/58 (36%)
leucine-rich repeat 272..295 CDD:275380 7/22 (32%)
leucine-rich repeat 296..319 CDD:275380 7/22 (32%)
LRR_8 319..380 CDD:290566 15/60 (25%)
leucine-rich repeat 320..343 CDD:275380 7/22 (32%)
leucine-rich repeat 344..369 CDD:275380 6/24 (25%)
LRR_8 368..428 CDD:290566 15/59 (25%)
leucine-rich repeat 370..393 CDD:275380 3/22 (14%)
leucine-rich repeat 394..417 CDD:275380 7/22 (32%)
leucine-rich repeat 418..441 CDD:275380 5/24 (21%)
LRRC39NP_001243314.1 LRR_RI 79..>263 CDD:238064 59/218 (27%)
LRR_8 84..141 CDD:290566 21/62 (34%)
LRR 1 84..105 6/21 (29%)
leucine-rich repeat 85..107 CDD:275380 5/22 (23%)
LRR 2 107..128 7/25 (28%)
leucine-rich repeat 108..127 CDD:275380 6/23 (26%)
LRR_8 129..188 CDD:290566 23/59 (39%)
LRR 3 130..151 8/21 (38%)
leucine-rich repeat 131..153 CDD:275380 7/22 (32%)
LRR 4 153..176 7/22 (32%)
leucine-rich repeat 154..177 CDD:275380 7/22 (32%)
LRR 5 177..197 9/46 (20%)
leucine-rich repeat 178..200 CDD:275380 9/48 (19%)
LRR 6 200..221 7/24 (29%)
leucine-rich repeat 201..223 CDD:275380 8/25 (32%)
LRR_8 223..280 CDD:290566 12/57 (21%)
LRR 7 223..244 4/20 (20%)
leucine-rich repeat 224..246 CDD:275380 4/21 (19%)
LRR 8 246..267 3/20 (15%)
leucine-rich repeat 247..269 CDD:275380 3/21 (14%)
LRR 9 269..290 5/11 (45%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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