DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and AgaP_AGAP005273

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:XP_309061.4 Gene:AgaP_AGAP005273 / 1270408 VectorBaseID:AGAP005273 Length:1405 Species:Anopheles gambiae


Alignment Length:435 Identity:130/435 - (29%)
Similarity:205/435 - (47%) Gaps:60/435 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 SEVASLQD--LVDLGAENWHTLAI-RNVQTELEVGSGENADHLANLLDLDLTGAAPINVHTNGFS 101
            :.||:|..  |..:..||...|:: |||..||   .|::......|:.||::|.:...:..:.|.
Mosquito   401 NRVAALSSSILKSIQPENIRYLSLSRNVIREL---PGDSFAAFRKLIYLDISGNSLGVIGEDTFK 462

  Fly   102 ILP-NLRQLNLSGCGLVDIRGNHFAPESALQRIDFSHNQMELLDRDFFGNLRKLIYANFSHN--- 162
            .|. .|.::.||...:..:| ....|:  |:|:|.|.|.::.|..|.|.:|..|:|.|.|.|   
Mosquito   463 GLEGTLLEIKLSFNRIASLR-KFVLPK--LRRLDLSANSIDDLAIDSFHSLHNLLYLNMSGNEHV 524

  Fly   163 ------------ALKQCDLPHMPL-LNRLELGHNRLVNATFGVCPQLQELILNDNQLIQLDVNAF 214
                        .|:..||.|..| :.:.:|.||.         ..|:..:||.|||..::...|
Mosquito   525 GQVTRTMIYPLTKLQVIDLSHCGLKMLQADLFHNN---------TDLRIALLNHNQLRVIEEGTF 580

  Fly   215 RGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVF-------------GAVQ 266
            ..|:.|.:|.|:||.|..:...:|.....||.|||.||||..||.::|             .|::
Mosquito   581 LNLNNLFDLSLAGNGLEQLRPRSFVNTVNLRTLNLRQNALQELRADMFTTETALEVLDASDNALK 645

  Fly   267 NFV-----LH--LQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLY 324
            :|.     :|  |:::.|:.||:.:........|..|:::|::.|.:.::....|..|.:||:||
Mosquito   646 SFATNTLKIHPRLRKVLLANNRLEVFPPELIADLDHLEVIDLAGNRLTTIQQLDFGRLANLRELY 710

  Fly   325 LQYNAILEIKPATFAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHL--HPLA 387
            |:.|.|..::...|.....|..|||:.|.||.|.|:.|.| || |:.||:|:.|::..|  ..||
Mosquito   711 LRANTIDSVQDMAFHNSSQLQILDLAANRLERLSERSFEG-TL-RLDRLDLSDNKLTGLPEQVLA 773

  Fly   388 FSSLPFLEYLKLGHNELKSLDVRMFAPMR-RLQKLHLGHNLLEEI 431
            .|.:..||.:.|..|:|.|:.|..|.... .||.|.|..|.:.|:
Mosquito   774 KSRVQRLERVSLAGNKLASVPVAAFGDQHDTLQTLDLSRNAIREV 818

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 52/169 (31%)
LRR_8 104..164 CDD:290566 19/75 (25%)
leucine-rich repeat 106..129 CDD:275380 5/22 (23%)
leucine-rich repeat 130..153 CDD:275380 9/22 (41%)
leucine-rich repeat 154..195 CDD:275380 13/56 (23%)
LRR_RI 194..455 CDD:238064 84/261 (32%)
LRR_8 194..254 CDD:290566 22/59 (37%)
leucine-rich repeat 196..219 CDD:275380 8/22 (36%)
leucine-rich repeat 220..243 CDD:275380 7/22 (32%)
leucine-rich repeat 244..267 CDD:275380 13/35 (37%)
LRR_8 271..330 CDD:290566 17/60 (28%)
leucine-rich repeat 272..295 CDD:275380 5/22 (23%)
leucine-rich repeat 296..319 CDD:275380 5/22 (23%)
LRR_8 319..380 CDD:290566 26/60 (43%)
leucine-rich repeat 320..343 CDD:275380 8/22 (36%)
leucine-rich repeat 344..369 CDD:275380 13/24 (54%)
LRR_8 368..428 CDD:290566 22/62 (35%)
leucine-rich repeat 370..393 CDD:275380 8/24 (33%)
leucine-rich repeat 394..417 CDD:275380 8/23 (35%)
leucine-rich repeat 418..441 CDD:275380 6/14 (43%)
AgaP_AGAP005273XP_309061.4 leucine-rich repeat 98..121 CDD:275380
LRR_RI <99..285 CDD:238064
LRR_8 124..187 CDD:290566
leucine-rich repeat 124..152 CDD:275380
leucine-rich repeat 153..176 CDD:275380
LRR_8 175..235 CDD:290566
leucine-rich repeat 177..200 CDD:275380
leucine-rich repeat 201..224 CDD:275380
LRR_8 224..283 CDD:290566
leucine-rich repeat 225..248 CDD:275380
leucine-rich repeat 249..272 CDD:275380
LRR_RI 273..522 CDD:238064 37/126 (29%)
LRR_8 273..329 CDD:290566
leucine-rich repeat 273..296 CDD:275380
leucine-rich repeat 297..320 CDD:275380
leucine-rich repeat 321..344 CDD:275380
leucine-rich repeat 345..368 CDD:275380
LRR_8 368..453 CDD:290566 17/54 (31%)
leucine-rich repeat 369..390 CDD:275380
leucine-rich repeat 393..413 CDD:275380 4/11 (36%)
leucine-rich repeat 420..442 CDD:275380 7/24 (29%)
LRR_8 441..521 CDD:290566 24/82 (29%)
leucine-rich repeat 443..488 CDD:275380 10/45 (22%)
leucine-rich repeat 468..482 CDD:275378 3/13 (23%)
LRR_8 487..548 CDD:290566 19/62 (31%)
leucine-rich repeat 489..512 CDD:275380 9/22 (41%)
leucine-rich repeat 538..561 CDD:275380 8/31 (26%)
LRR_8 562..620 CDD:290566 22/57 (39%)
leucine-rich repeat 562..585 CDD:275380 8/22 (36%)
leucine-rich repeat 586..609 CDD:275380 7/22 (32%)
leucine-rich repeat 610..633 CDD:275380 12/22 (55%)
leucine-rich repeat 634..657 CDD:275380 3/22 (14%)
LRR_8 656..714 CDD:290566 15/57 (26%)
leucine-rich repeat 658..681 CDD:275380 5/22 (23%)
LRR_RI 674..935 CDD:238064 50/147 (34%)
leucine-rich repeat 682..705 CDD:275380 5/22 (23%)
LRR_8 705..764 CDD:290566 26/60 (43%)
leucine-rich repeat 706..729 CDD:275380 8/22 (36%)
LRR <725..>917 CDD:227223 36/96 (38%)
leucine-rich repeat 730..753 CDD:275380 13/24 (54%)
leucine-rich repeat 754..773 CDD:275380 5/18 (28%)
leucine-rich repeat 780..804 CDD:275380 8/23 (35%)
leucine-rich repeat 805..869 CDD:275380 6/14 (43%)
leucine-rich repeat 870..898 CDD:275380
LRR_8 873..935 CDD:290566
leucine-rich repeat 899..924 CDD:275380
leucine-rich repeat 925..946 CDD:275380
leucine-rich repeat 949..971 CDD:275380
leucine-rich repeat 1000..1022 CDD:275380
leucine-rich repeat 1025..1046 CDD:275380
LRRCT 1112..1159 CDD:214507
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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