DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and lrrc26

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	XP_031746479.1	Gene:	lrrc26 / 116406528	-ID:	-	Length:	304	Species:	Xenopus tropicalis

Alignment Length:	197	Identity:	60/197 - (30%)
Similarity:	94/197 - (47%)	Gaps:	33/197 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   346 TLDLSYNNLEFLEEQIFGGNTLPRMRR---LNLNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSL 407
            |:.|.||::..:.     |..|.|.||   |:|..||:..:|..||.....|.||.|..|:|.::
Frog    53 TVLLGYNHIGAIT-----GLCLQRYRRMEHLDLRSNRISTIHSRAFRYQQNLTYLDLSANQLATI 112

  Fly   408 DVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLA-KVNVSFPNLKRVAIE 471
            ...:|.|:..|..|.||:|.:.|:....|:|..::..:.:.||.||.|| .:..:..||:.:.::
Frog   113 PAELFRPLANLLTLDLGNNRISELPGSALDSSLALDTLYLHNNALTGLAGPLLGNLGNLRHLRLD 177

  Fly   472 GNPWQCPCFVK-LQHWLATR-DVVYLRDNT--GY--YKGERPLCIVTNVDYCIQNLQAVRRLGIL 530
            ||||.|.|.:: |.:|:... :.:..||.|  |:  |..:.||                  |||.
Frog   178 GNPWACTCQIQTLLNWIKQNPERLEERDRTLCGFPGYLDQYPL------------------LGIQ 224

  Fly   531 GD 532
            ||
Frog   225 GD 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064
		LRR_8	104..164	CDD:290566
		leucine-rich repeat	106..129	CDD:275380
		leucine-rich repeat	130..153	CDD:275380
		leucine-rich repeat	154..195	CDD:275380
		LRR_RI	194..455	CDD:238064	36/111 (32%)
		LRR_8	194..254	CDD:290566
		leucine-rich repeat	196..219	CDD:275380
		leucine-rich repeat	220..243	CDD:275380
		leucine-rich repeat	244..267	CDD:275380
		LRR_8	271..330	CDD:290566
		leucine-rich repeat	272..295	CDD:275380
		leucine-rich repeat	296..319	CDD:275380
		LRR_8	319..380	CDD:290566	12/36 (33%)
		leucine-rich repeat	320..343	CDD:275380
		leucine-rich repeat	344..369	CDD:275380	6/22 (27%)
		LRR_8	368..428	CDD:290566	23/62 (37%)
		leucine-rich repeat	370..393	CDD:275380	9/25 (36%)
		leucine-rich repeat	394..417	CDD:275380	8/22 (36%)
		leucine-rich repeat	418..441	CDD:275380	8/22 (36%)
lrrc26	XP_031746479.1	LRR	<51..>196	CDD:227223	48/147 (33%)
		leucine-rich repeat	52..74	CDD:275380	7/25 (28%)
		leucine-rich repeat	75..98	CDD:275380	7/22 (32%)
		leucine-rich repeat	99..122	CDD:275380	8/22 (36%)
		leucine-rich repeat	123..146	CDD:275380	8/22 (36%)
		leucine-rich repeat	147..170	CDD:275380	6/22 (27%)
		TPKR_C2	179..232	CDD:417692	19/66 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7602
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000