Protein Alignment CG6749 and LOC11175769

DIOPT Version :10

• Sequence 1: NP_648354.1
• Gene: CG6749 / 39144
• FlyBaseID: FBgn0036040
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: XP_061505893.1
• Gene: LOC11175769 / 11175769
• VectorBaseID: AGAMI1_008733
• Length: 1080
• Species: Anopheles gambiae
• Alignment Length: 577
• Identity: 139/577 - (24%)
• Similarity: 232/577 - (40%)
• Gaps: 161/577 - (27%)

  Fly     3 QTANW-VLPLLLWLLC--MG--------FPILHGADLCQPIGWRNFQCSEVASLQDLVDLGAENW 56
            :||.: |:.|||.::|  :|        ||::    |.:.|     |.....|.:.||......:
Mosquito   463 KTAEYVVIALLLCMVCGLLGKLFVDSRYFPVV----LKERI-----QRRTSISHESLVSCDLNGY 518

  Fly    57 HTLAIRNVQTELEVGSGENAD------HLANLLDLDLTGAAPINVHTNGFSILP-NLRQLNLSGC 114
            ..:.|    |...|.|.::||      |.|:.:.:: ..:..:| |...|  .| |:..:|
Mosquito   519 LLVGI----TLSAVVSFDSADAALCMCHPASCVVIN-ANSTVLN-HPEMF--CPANIMNIN---- 571

  Fly   115 GLVDIRGN-------HFAPESALQRIDFSHNQMELLDRDFFGNLRKLIYANFSHNALKQCDLPHM 172
            .|:.:|.|       .|||.:.|..|:.           |.|:|.::....|...
Mosquito   572 DLLILRYNDTILTVDSFAPFTNLTSIEI-----------FQGSLSRIEPGAFEKT---------- 615

  Fly   173 PLLNRLELGHN---RLVNATFGVCPQLQELILNDNQLIQLDVNAFRGLHGLLELQLSGNRLSSIG 234
            |.|.::.:..|   .|.:.||.....|..|.|..|.|..:..|||.||..|.:|.||||:::.:.
Mosquito   616 PALFKIIIRSNVLSALEDYTFRGLDALHILYLISNNLTSIAPNAFYGLKNLTQLVLSGNQIAQLP 680

  Fly   235 LETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQLDLSGNRIR----------LLF--D 287
            ...|.....||.::||.|.|..|...:|.::.    :|.:||||.|:::          |||  :
Mosquito   681 PTLFSSTPMLRSVSLSNNMLTELPAGIFDSID----YLFKLDLSYNQLKTFDFPDLKVTLLFLHN 741

  Fly   288 NQFRVL---ARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDL 349
            |....|   ..::::..:.|.||.||.:.|    ::..|.|..|||.::.|  ...:.|:..|.|
Mosquito   742 NSLTSLHVGDHVKVVQANHNRIAKLSGSGF----NITDLLLSDNAITDVTP--IMLMKNISKLSL 800

  Fly   350 SYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSLDVRMFAP 414
            |.|.|:  .:.:||  :|.::..|.|:...:. ::...|::|.::..|.|.:|.:..||.|||:.
Mosquito   801 SNNPLQ--PDSVFG--SLEQLEELFLSHTSIM-INEQTFANLSWMSLLDLSYNNMTELDFRMFSS 860

  Fly   415 MRRLQKLHLGHNLLEEIN-LDVLESLSSVQEILVDNNRLTFLAKVNVSFPNLKRVAIEGNPWQCP 478
            |.:|:.|.:.:|.:|.|| :::.|.|                       |.|:.:.|.||.|
Mosquito   861 MNKLKSLIVAYNRIETINFIELREYL-----------------------PELRVLEICGNGW--- 899

  Fly   479 CFVKLQHWLATRDVVYLRDNTGYYKGERPLCIVTNVDYCIQNLQAVRRLGILGDFQG 535
                                              |..|..:.|..:|:..:..|.||
Mosquito   900 ----------------------------------NATYMERMLSKMRKHKLRADMQG 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_8	104..164	CDD:404697	15/67 (22%)
		leucine-rich repeat	106..129	CDD:275380	7/29 (24%)
		leucine-rich repeat	130..153	CDD:275380	5/22 (23%)
		leucine-rich repeat	154..195	CDD:275380	7/43 (16%)
		leucine-rich repeat	196..219	CDD:275380	10/22 (45%)
		LRR	199..>452	CDD:443914	77/268 (29%)
		leucine-rich repeat	220..243	CDD:275380	7/22 (32%)
		leucine-rich repeat	244..267	CDD:275380	8/22 (36%)
		leucine-rich repeat	272..295	CDD:275380	11/37 (30%)
		leucine-rich repeat	296..319	CDD:275380	6/22 (27%)
		leucine-rich repeat	320..343	CDD:275380	6/22 (27%)
		leucine-rich repeat	344..369	CDD:275380	8/24 (33%)
		leucine-rich repeat	370..393	CDD:275380	4/22 (18%)
		leucine-rich repeat	394..417	CDD:275380	9/22 (41%)
		leucine-rich repeat	418..441	CDD:275380	8/23 (35%)
LOC11175769	XP_061505893.1	None