DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and lrrc53

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:XP_021322571.1 Gene:lrrc53 / 101882576 ZFINID:ZDB-GENE-131121-432 Length:838 Species:Danio rerio


Alignment Length:271 Identity:77/271 - (28%)
Similarity:117/271 - (43%) Gaps:41/271 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   210 DVNAFRGLHGLLE-------LQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQN 267
            ||...:.|..:::       |.|:...:.|:|...|..|:.:..|.||.||:.::..|.|   ||
Zfish    31 DVTICQKLRSIIDAPGSTKALMLTDGLIDSVGSMVFSDLSNMSVLALSNNAISSITENAF---QN 92

  Fly   268 FVLHLQQLDLSGNRI--RLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAI 330
            ... |..|.|..|.|  :.|..:.|..|.||:.|.:|.|.:..:..:.|....:|:.|.|..|.:
Zfish    93 LTF-LTTLSLDHNHISNQALNSSTFSWLHRLETLQLSNNHLKDIDGSWFQSSIALKTLQLDGNLL 156

  Fly   331 LEIKPATF--AALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPF 393
            ..:...||  |.|.||:.||||.|.:..|..:.|  ..||.:|||:|:.|.:... |.|||.|.:
Zfish   157 TSLNSTTFAHADLRNLEILDLSDNLIVTLGRESF--RRLPSLRRLDLSRNNLSSA-PDAFSYLSW 218

  Fly   394 LEYLKLGHNELK-SLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAK 457
            |..|.|..|... |.::|..|                    ..|.|.....|.::.|.:.  :|.
Zfish   219 LSTLNLDLNRWSCSCELRELA--------------------SFLNSFIQAPENVLYNGQK--MAC 261

  Fly   458 VNVSFPNLKRV 468
            ||...|:::.|
Zfish   262 VNADNPSVQTV 272

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 14/52 (27%)
LRR_8 104..164 CDD:290566
leucine-rich repeat 106..129 CDD:275380
leucine-rich repeat 130..153 CDD:275380
leucine-rich repeat 154..195 CDD:275380
LRR_RI 194..455 CDD:238064 72/256 (28%)
LRR_8 194..254 CDD:290566 13/50 (26%)
leucine-rich repeat 196..219 CDD:275380 3/8 (38%)
leucine-rich repeat 220..243 CDD:275380 6/29 (21%)
leucine-rich repeat 244..267 CDD:275380 7/22 (32%)
LRR_8 271..330 CDD:290566 18/60 (30%)
leucine-rich repeat 272..295 CDD:275380 8/24 (33%)
leucine-rich repeat 296..319 CDD:275380 5/22 (23%)
LRR_8 319..380 CDD:290566 24/62 (39%)
leucine-rich repeat 320..343 CDD:275380 8/24 (33%)
leucine-rich repeat 344..369 CDD:275380 9/24 (38%)
LRR_8 368..428 CDD:290566 18/60 (30%)
leucine-rich repeat 370..393 CDD:275380 10/22 (45%)
leucine-rich repeat 394..417 CDD:275380 7/23 (30%)
leucine-rich repeat 418..441 CDD:275380 2/22 (9%)
lrrc53XP_021322571.1 LRR_8 49..106 CDD:316378 19/60 (32%)
leucine-rich repeat 51..71 CDD:275380 6/19 (32%)
leucine-rich repeat 72..95 CDD:275380 9/25 (36%)
LRR_8 96..156 CDD:316378 18/59 (31%)
leucine-rich repeat 96..121 CDD:275380 8/24 (33%)
leucine-rich repeat 122..145 CDD:275380 5/22 (23%)
LRR_8 146..206 CDD:316378 24/61 (39%)
leucine-rich repeat 146..171 CDD:275380 8/24 (33%)
leucine-rich repeat 172..195 CDD:275380 9/24 (38%)
leucine-rich repeat 196..218 CDD:275380 10/22 (45%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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