Protein Alignment CG6749 and lrrc53

DIOPT Version :10

• Sequence 1: NP_648354.1
• Gene: CG6749 / 39144
• FlyBaseID: FBgn0036040
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: XP_021322571.1
• Gene: lrrc53 / 101882576
• ZFINID: ZDB-GENE-131121-432
• Length: 838
• Species: Danio rerio
• Alignment Length: 271
• Identity: 77/271 - (28%)
• Similarity: 117/271 - (43%)
• Gaps: 41/271 - (15%)

  Fly   210 DVNAFRGLHGLLE-------LQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQN 267
            ||...:.|..:::       |.|:...:.|:|...|..|:.:..|.||.||:.::..|.|   ||
Zfish    31 DVTICQKLRSIIDAPGSTKALMLTDGLIDSVGSMVFSDLSNMSVLALSNNAISSITENAF---QN 92

  Fly   268 FVLHLQQLDLSGNRI--RLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAI 330
            ... |..|.|..|.|  :.|..:.|..|.||:.|.:|.|.:..:..:.|....:|:.|.|..|.:
Zfish    93 LTF-LTTLSLDHNHISNQALNSSTFSWLHRLETLQLSNNHLKDIDGSWFQSSIALKTLQLDGNLL 156

  Fly   331 LEIKPATF--AALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPF 393
            ..:...||  |.|.||:.||||.|.:..|..:.|  ..||.:|||:|:.|.:... |.|||.|.:
Zfish   157 TSLNSTTFAHADLRNLEILDLSDNLIVTLGRESF--RRLPSLRRLDLSRNNLSSA-PDAFSYLSW 218

  Fly   394 LEYLKLGHNELK-SLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAK 457
            |..|.|..|... |.::|..|                    ..|.|.....|.::.|.:.  :|.
Zfish   219 LSTLNLDLNRWSCSCELRELA--------------------SFLNSFIQAPENVLYNGQK--MAC 261

  Fly   458 VNVSFPNLKRV 468
            ||...|:::.|
Zfish   262 VNADNPSVQTV 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_8	104..164	CDD:404697
		leucine-rich repeat	106..129	CDD:275380
		leucine-rich repeat	130..153	CDD:275380
		leucine-rich repeat	154..195	CDD:275380
		leucine-rich repeat	196..219	CDD:275380	3/8 (38%)
		LRR	199..>452	CDD:443914	72/253 (28%)
		leucine-rich repeat	220..243	CDD:275380	6/29 (21%)
		leucine-rich repeat	244..267	CDD:275380	7/22 (32%)
		leucine-rich repeat	272..295	CDD:275380	8/24 (33%)
		leucine-rich repeat	296..319	CDD:275380	5/22 (23%)
		leucine-rich repeat	320..343	CDD:275380	8/24 (33%)
		leucine-rich repeat	344..369	CDD:275380	9/24 (38%)
		leucine-rich repeat	370..393	CDD:275380	10/22 (45%)
		leucine-rich repeat	394..417	CDD:275380	7/23 (30%)
		leucine-rich repeat	418..441	CDD:275380	2/22 (9%)
lrrc53	XP_021322571.1	LRR	38..>228	CDD:443914	62/196 (32%)
		leucine-rich repeat	51..71	CDD:275380	6/19 (32%)
		leucine-rich repeat	72..95	CDD:275380	9/25 (36%)
		leucine-rich repeat	96..121	CDD:275380	8/24 (33%)
		leucine-rich repeat	122..145	CDD:275380	5/22 (23%)
		leucine-rich repeat	146..171	CDD:275380	8/24 (33%)
		leucine-rich repeat	172..195	CDD:275380	9/24 (38%)
		leucine-rich repeat	196..218	CDD:275380	10/22 (45%)
		Atrophin-1	622..>785	CDD:460830