DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6749 and mxra5

DIOPT Version :9

Sequence 1:	NP_648354.1	Gene:	CG6749 / 39144	FlyBaseID:	FBgn0036040	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	XP_002941051.4	Gene:	mxra5 / 100495231	XenbaseID:	XB-GENE-923372	Length:	2851	Species:	Xenopus tropicalis

Alignment Length:	354	Identity:	83/354 - (23%)
Similarity:	148/354 - (41%)	Gaps:	71/354 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 FRGLHGLLELQLSGNRLSSIGLETFQPLAQLRKLNLSQNALDALRP-------------NVFGAV 265
            :.|..|..:|....|     |:..:..||.:  :.:.||||....|             ....||
Frog     9 YTGTQGKKKLSKMYN-----GIHLWLILAVI--IFVPQNALSCPHPCACYVNSEVHCTFRSLAAV 66

  Fly   266 QNFV-LHLQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNA 329
            .:.: .|:::::|..|.|:.:.::.|..|::|::|.:..|.:.::....|..|.||:...:.||.
Frog    67 PSRIPKHVERINLGFNSIQSIGEDSFAGLSKLELLLIHSNDVRNVPNGAFRDLVSLQVFKMSYNK 131

  Fly   330 ILEIKPATFAALLNLDTLDLSYNNLEFLEEQIFGGNTLPRMRRLNLNGNRMKHLHPLAFSSLPFL 394
            :..|...|...||.|..|.:.:|.:||:....|.|  |..:|.|:|.||.::.||...|.:..||
Frog   132 LKTITSHTLHGLLGLTRLHIDHNQIEFIHPNAFNG--LMSLRLLHLEGNLLQQLHANTFCTFNFL 194

  Fly   395 EYLKLGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKVN 459
            .|.:                ...|:.|:|..|:::.:..|:::::
Frog   195 GYFR----------------QSTLKHLYLSENMIQSLPADMIKTM-------------------- 223

  Fly   460 VSFPNLKRVAIEGNPWQCPCFVK-LQHWLATRD-VVYLRDNTGYYKGERPLCIVTNVDYCIQNLQ 522
               |.|:.:.:.||||.|.|.:| |..|....| ::..:.:..|..|:  ||...:....:||
Frog   224 ---PLLENLYLHGNPWVCDCNIKWLLDWTEQTDGILKCKKDRSYENGQ--LCPTCSSPKHLQN-- 281

  Fly   523 AVRRLGILGD-FQGEQVEADAFDDDASAA 550
              |.:..|.| :....|...|..|::|.|
Frog   282 --REIQSLKDAYCSRPVIYSALRDNSSYA 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6749	NP_648354.1	LRR_RI	103..>256	CDD:238064	11/41 (27%)
		LRR_8	104..164	CDD:290566
		leucine-rich repeat	106..129	CDD:275380
		leucine-rich repeat	130..153	CDD:275380
		leucine-rich repeat	154..195	CDD:275380
		LRR_RI	194..455	CDD:238064	57/254 (22%)
		LRR_8	194..254	CDD:290566	9/39 (23%)
		leucine-rich repeat	196..219	CDD:275380	1/4 (25%)
		leucine-rich repeat	220..243	CDD:275380	4/22 (18%)
		leucine-rich repeat	244..267	CDD:275380	7/35 (20%)
		LRR_8	271..330	CDD:290566	15/58 (26%)
		leucine-rich repeat	272..295	CDD:275380	5/22 (23%)
		leucine-rich repeat	296..319	CDD:275380	5/22 (23%)
		LRR_8	319..380	CDD:290566	21/60 (35%)
		leucine-rich repeat	320..343	CDD:275380	6/22 (27%)
		leucine-rich repeat	344..369	CDD:275380	8/24 (33%)
		LRR_8	368..428	CDD:290566	15/59 (25%)
		leucine-rich repeat	370..393	CDD:275380	8/22 (36%)
		leucine-rich repeat	394..417	CDD:275380	2/22 (9%)
		leucine-rich repeat	418..441	CDD:275380	5/22 (23%)
mxra5	XP_002941051.4	LRRNT	44..75	CDD:214470	4/30 (13%)
		leucine-rich repeat	55..72	CDD:275380	2/16 (13%)
		leucine-rich repeat	74..97	CDD:275380	5/22 (23%)
		PPP1R42	82..238	CDD:411060	47/196 (24%)
		LRR_8	96..156	CDD:404697	16/59 (27%)
		leucine-rich repeat	98..121	CDD:275380	5/22 (23%)
		leucine-rich repeat	122..145	CDD:275380	6/22 (27%)
		leucine-rich repeat	146..169	CDD:275380	8/24 (33%)
		leucine-rich repeat	170..201	CDD:275380	11/46 (24%)
		leucine-rich repeat	202..225	CDD:275380	5/45 (11%)
		LRRCT	234..293	CDD:214507	18/64 (28%)
		IG	511..584	CDD:214652
		IG	598..680	CDD:214652
		Herpes_BLLF1	<1269..1567	CDD:282904
		Ig	1895..1959	CDD:409353
		Ig strand B	1895..1899	CDD:409353
		Ig strand C	1908..1912	CDD:409353
		Ig strand E	1935..1939	CDD:409353
		Ig strand F	1949..1954	CDD:409353
		Ig	1989..2066	CDD:416386
		Ig strand B	1991..1999	CDD:409353
		Ig strand C	2005..2010	CDD:409353
		Ig strand C'	2013..2015	CDD:409353
		Ig strand D	2025..2029	CDD:409353
		Ig strand E	2032..2036	CDD:409353
		Ig strand F	2046..2053	CDD:409353
		Ig strand G	2056..2066	CDD:409353
		Ig	2072..2163	CDD:416386
		Ig strand A	2072..2075	CDD:409353
		Ig strand A'	2080..2083	CDD:409353
		Ig strand B	2089..2096	CDD:409353
		Ig strand C	2102..2108	CDD:409353
		Ig strand C'	2110..2112	CDD:409353
		Ig strand D	2122..2126	CDD:409353
		Ig strand E	2129..2134	CDD:409353
		Ig strand F	2142..2150	CDD:409353
		Ig strand G	2153..2163	CDD:409353
		Ig	2172..2252	CDD:416386
		Ig strand A	2172..2175	CDD:409353
		Ig strand A'	2179..2182	CDD:409353
		Ig strand B	2188..2195	CDD:409353
		Ig strand C	2201..2210	CDD:409353
		Ig strand C'	2212..2214	CDD:409353
		Ig strand D	2221..2225	CDD:409353
		Ig strand E	2228..2233	CDD:409353
		Ig strand F	2241..2249	CDD:409353
		Ig	2279..2365	CDD:416386
		Ig strand B	2284..2292	CDD:409353
		Ig strand C	2298..2303	CDD:409353
		Ig strand C'	2306..2308	CDD:409353
		Ig strand D	2324..2328	CDD:409353
		Ig strand E	2331..2335	CDD:409353
		Ig strand F	2345..2352	CDD:409353
		Ig strand G	2355..2365	CDD:409353
		Ig strand A	2369..2372	CDD:409353
		Ig strand A'	2377..2381	CDD:409353
		I-set	2382..2459	CDD:400151
		Ig strand B	2387..2396	CDD:409353
		Ig strand C	2401..2406	CDD:409353
		Ig strand C'	2409..2411	CDD:409353
		Ig strand D	2419..2422	CDD:409353
		Ig strand E	2425..2432	CDD:409353
		Ig strand F	2438..2446	CDD:409353
		Ig strand G	2449..2459	CDD:409353
Ig	2475..2559	CDD:416386
Ig strand A'	2476..2479	CDD:409353
Ig strand B	2485..2493	CDD:409353
Ig strand C	2499..2504	CDD:409353
Ig strand C'	2507..2509	CDD:409353
Ig strand D	2518..2522	CDD:409353
Ig strand E	2525..2529	CDD:409353
Ig strand F	2539..2546	CDD:409353
Ig strand G	2549..2559	CDD:409353
Ig_3	2565..2643	CDD:404760
Ig strand A'	2574..2577	CDD:409353
Ig strand B	2583..2590	CDD:409353
Ig strand C	2596..2608	CDD:409353
Ig strand C'	2611..2613	CDD:409353
Ig strand D	2617..2620	CDD:409353
Ig strand E	2622..2626	CDD:409353
Ig strand F	2635..2643	CDD:409353
Ig_3	2659..2737	CDD:404760
Ig strand B	2678..2682	CDD:409353
Ig strand C	2691..2695	CDD:409353
Ig strand E	2717..2721	CDD:409353
Ig strand F	2731..2736	CDD:409353
Ig_3	2755..2837	CDD:404760
Ig strand A	2755..2759	CDD:409353
Ig strand A'	2764..2768	CDD:409353
Ig strand B	2772..2781	CDD:409353
Ig strand C	2787..2796	CDD:409353
Ig strand C'	2802..2805	CDD:409353
Ig strand E	2816..2822	CDD:409353
Ig strand F	2829..2837	CDD:409353
Ig strand G	2842..2850	CDD:409353
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910