DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and tlr9

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:XP_017948709.2 Gene:tlr9 / 100494387 XenbaseID:XB-GENE-486908 Length:1035 Species:Xenopus tropicalis


Alignment Length:589 Identity:128/589 - (21%)
Similarity:222/589 - (37%) Gaps:194/589 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 HGADLCQPIGWRN----------FQCSEVASLQDLVDLGAENWHTLAIRNVQTELEVGSGENADH 78
            |....|.|.  :|          |.|....|   .::|...:.|||     .:.| ..|..|..|
 Frog   263 HALQACYPC--KNNSALLLVPGVFDCLHKLS---YLNLRGNSLHTL-----HSSL-FSSLTNLSH 316

  Fly    79 LA---NLLDLDLTGAAPINVHTNGFSILPNLRQLNLSGCGLVDIRGNHFAPESALQRIDFSHN-- 138
            |.   |.|:|:.         ...||.|.|:::|||.         .:|.|.|..:|:..:.|  
 Frog   317 LVLSDNFLNLET---------ETFFSALTNVKELNLD---------FNFKPYSMYERLVLNSNVA 363

  Fly   139 QMELLDRDFFGNLRKLIYANFSHNALKQCDLPHMPLLNRLELGHNRLVNATFGVCPQLQELILND 203
            :|:.|:|        :....:..|.|.:..:  ||||:                .|.|:|:.|..
 Frog   364 RMKSLER--------ITIVGYFFNVLDEEGI--MPLLS----------------LPNLREISLRT 402

  Fly   204 NQLIQLDVN------------------AFR--------GLH------------------------ 218
            |.:::::::                  :|.        .:|                        
 Frog   403 NFILKVNLSMLFTHKPLRFISLSENLISFEEHKHGQKLAMHPPLFDRGNQVDGGWMDSHCGPKQV 467

  Fly   219 --GLLE----------LQLSGNRLSSIGLETFQPLAQLRKLNLSQNALD-ALRPNVFGAVQNFVL 270
              |.:|          :.||.|.:.||..:.|..:.::..||:|.|.:: .|....||.:::   
 Frog   468 EAGEVEYPGCWQYNHSVDLSFNNIGSIYPDEFLGMDEIECLNMSYNYINQRLNGTQFGHLKS--- 529

  Fly   271 HLQQLDLSGNRIRLLFDNQFRVLARLQMLDVSRN--------------------SIASLS-PAHF 314
             |:.||||.||..:.:......|.||::|:::.|                    |:..|: ..:|
 Frog   530 -LRHLDLSHNRFDMYYYKALSELPRLKILNLAHNDYQFMMKGVNHRLDFLENLTSLVELNLNNNF 593

  Fly   315 VGLGSLRKL-----------------YLQYNAILEIKPATFAALLNLDTLDLSYNNLEFLEEQIF 362
            :||...|:|                 ..||.....:.  .|..|.:|..||:|||.|..:..::.
 Frog   594 IGLRITRELKSHSLETLRFRNNELGSSWQYGKDTYLN--MFTNLRSLKILDISYNQLPVIPNEVL 656

  Fly   363 GGNTLPR-MRRLNLNGNRMKHLHPLAFSSLPFLEYLKLGHNELKSLDVRMFAPMRRLQKLHLGHN 426
              ..||. :::|||:.|::...:....:.|..|..|.||.|.|..|  |.......:..|:|.:|
 Frog   657 --EKLPESLQKLNLSHNKLYTFNWAKTAHLGNLAILDLGFNALTKL--RANLTESNIAFLNLTYN 717

  Fly   427 LLEEINLDVLESLSSVQEILVDNNRLTFLAKVNV-SFP-----NLKRVAIEGNPWQCPCFVKLQH 485
            .:..::.|..:|.|.::::::.||   .:..::: |||     ||..:.:.|||:||.|   ..:
 Frog   718 KINSLDKDFFDSFSELKQLILSNN---LIKTIHITSFPINFLQNLDSLDVSGNPFQCTC---KAY 776

  Fly   486 WLAT 489
            |..|
 Frog   777 WFIT 780

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 38/217 (18%)
LRR_8 104..164 CDD:290566 13/61 (21%)
leucine-rich repeat 106..129 CDD:275380 5/22 (23%)
leucine-rich repeat 130..153 CDD:275380 5/24 (21%)
leucine-rich repeat 154..195 CDD:275380 6/40 (15%)
LRR_RI 194..455 CDD:238064 75/362 (21%)
LRR_8 194..254 CDD:290566 19/121 (16%)
leucine-rich repeat 196..219 CDD:275380 6/74 (8%)
leucine-rich repeat 220..243 CDD:275380 7/32 (22%)
leucine-rich repeat 244..267 CDD:275380 7/23 (30%)
LRR_8 271..330 CDD:290566 21/96 (22%)
leucine-rich repeat 272..295 CDD:275380 8/22 (36%)
leucine-rich repeat 296..319 CDD:275380 8/43 (19%)
LRR_8 319..380 CDD:290566 19/78 (24%)
leucine-rich repeat 320..343 CDD:275380 6/39 (15%)
leucine-rich repeat 344..369 CDD:275380 8/24 (33%)
LRR_8 368..428 CDD:290566 17/60 (28%)
leucine-rich repeat 370..393 CDD:275380 5/22 (23%)
leucine-rich repeat 394..417 CDD:275380 8/22 (36%)
leucine-rich repeat 418..441 CDD:275380 5/22 (23%)
tlr9XP_017948709.2 leucine-rich repeat 69..92 CDD:275380
PLN00113 82..>592 CDD:215061 76/387 (20%)
leucine-rich repeat 93..128 CDD:275380
leucine-rich repeat 129..148 CDD:275380
leucine-rich repeat 149..172 CDD:275380
leucine-rich repeat 173..203 CDD:275380
leucine-rich repeat 204..224 CDD:275380
leucine-rich repeat 225..248 CDD:275380
leucine-rich repeat 249..289 CDD:275380 6/27 (22%)
leucine-rich repeat 290..311 CDD:275380 6/29 (21%)
leucine-rich repeat 314..337 CDD:275380 8/31 (26%)
leucine-rich repeat 353..394 CDD:275380 11/66 (17%)
leucine-rich repeat 395..418 CDD:275380 4/22 (18%)
leucine-rich repeat 482..504 CDD:275380 6/21 (29%)
leucine-rich repeat 505..529 CDD:275380 7/23 (30%)
leucine-rich repeat 530..553 CDD:275380 8/22 (36%)
inl_like_NEAT_1 <534..>767 CDD:411101 56/241 (23%)
leucine-rich repeat 554..583 CDD:275380 3/28 (11%)
leucine-rich repeat 584..637 CDD:275380 10/54 (19%)
leucine-rich repeat 607..629 CDD:275380 2/21 (10%)
leucine-rich repeat 638..662 CDD:275380 9/25 (36%)
leucine-rich repeat 663..686 CDD:275380 5/22 (23%)
leucine-rich repeat 687..708 CDD:275380 8/22 (36%)
leucine-rich repeat 709..732 CDD:275380 5/22 (23%)
leucine-rich repeat 733..751 CDD:275380 2/20 (10%)
PCC 738..>821 CDD:188093 15/49 (31%)
TIR_2 875..1017 CDD:419986
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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