DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6749 and lingo1

DIOPT Version :9

Sequence 1:NP_648354.1 Gene:CG6749 / 39144 FlyBaseID:FBgn0036040 Length:552 Species:Drosophila melanogaster
Sequence 2:NP_001093719.1 Gene:lingo1 / 100101739 XenbaseID:XB-GENE-921957 Length:606 Species:Xenopus tropicalis


Alignment Length:342 Identity:95/342 - (27%)
Similarity:150/342 - (43%) Gaps:60/342 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   168 DLPH-MPLLNR-LELGHNR---LVNATFGVCPQLQELILNDNQLIQLDVNAFRGLHGLLELQLSG 227
            |:|. :|...| |:|..||   |....|...|.|:||.||:|.:..::..||.||..|..|.|..
 Frog    50 DVPEGIPTDTRLLDLSKNRIKALNQDEFSAFPYLEELELNENIVSIIEPGAFNGLFNLRSLGLRS 114

  Fly   228 NRLSSIGLETFQPLAQLRKLNLSQNALDALRPNVFGAVQNFVLHLQQLDLSGNRIRLLFDNQFRV 292
            |||..|.|..|..|:                            :|.|||:|.|:|.:|.|:.|:.
 Frog   115 NRLKLIPLGVFTGLS----------------------------NLTQLDISENKIVILLDDMFQD 151

  Fly   293 LARLQMLDVSRNSIASLSPAHFVGLGSLRKLYLQYNAILEIKPATFAALLNLDTLDLSYNNLEFL 357
            |..|:.|:|..|.:..:|...|.||.||.:|.|:...:..:.....:.|..|.||.|.|.|:..:
 Frog   152 LYNLKSLEVGDNDLVYISHRAFRGLNSLEELTLEKCNLTSVPTEALSHLHGLITLKLRYLNINVI 216

  Fly   358 EEQIFGGNTLPRMRRLNL-----------NGNRMKHLHPLA-----FSSLP--------FLEYLK 398
            .:..|  ..|.|::.|.:           ||....:|..|:     .||:|        :|.:|.
 Frog   217 RDYSF--KRLYRLKNLEIAHWPYLDTMTSNGLYGLNLTSLSITHSNLSSIPYVAIRHLVYLRFLN 279

  Fly   399 LGHNELKSLDVRMFAPMRRLQKLHLGHNLLEEINLDVLESLSSVQEILVDNNRLTFLAKVNV-SF 462
            |.:|.:.:::..|...:.|||:.||....|..:.......|:.::.:.|.:|.|:.|.:.:. |.
 Frog   280 LSYNPITAVEGSMLYELLRLQEFHLVGGQLSVVEPYAFRGLNHLKVLNVSSNYLSTLEESSFHSV 344

  Fly   463 PNLKRVAIEGNPWQCPC 479
            .||:.:.::.||..|.|
 Frog   345 GNLETLILDKNPLACDC 361

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6749NP_648354.1 LRR_RI 103..>256 CDD:238064 31/92 (34%)
LRR_8 104..164 CDD:290566
leucine-rich repeat 106..129 CDD:275380
leucine-rich repeat 130..153 CDD:275380
leucine-rich repeat 154..195 CDD:275380 10/31 (32%)
LRR_RI 194..455 CDD:238064 77/284 (27%)
LRR_8 194..254 CDD:290566 21/59 (36%)
leucine-rich repeat 196..219 CDD:275380 10/22 (45%)
leucine-rich repeat 220..243 CDD:275380 10/22 (45%)
leucine-rich repeat 244..267 CDD:275380 0/22 (0%)
LRR_8 271..330 CDD:290566 23/58 (40%)
leucine-rich repeat 272..295 CDD:275380 11/22 (50%)
leucine-rich repeat 296..319 CDD:275380 8/22 (36%)
LRR_8 319..380 CDD:290566 17/71 (24%)
leucine-rich repeat 320..343 CDD:275380 4/22 (18%)
leucine-rich repeat 344..369 CDD:275380 8/24 (33%)
LRR_8 368..428 CDD:290566 19/83 (23%)
leucine-rich repeat 370..393 CDD:275380 8/46 (17%)
leucine-rich repeat 394..417 CDD:275380 5/22 (23%)
leucine-rich repeat 418..441 CDD:275380 6/22 (27%)
lingo1NP_001093719.1 LRRNT 27..61 CDD:214470 3/10 (30%)
LRR 1 58..79 7/20 (35%)
leucine-rich repeat 59..82 CDD:275380 7/22 (32%)
PLN00113 62..>381 CDD:215061 91/330 (28%)
LRR 2 82..103 8/20 (40%)
leucine-rich repeat 83..106 CDD:275380 10/22 (45%)
LRR_8 106..165 CDD:338972 25/86 (29%)
LRR 3 106..127 9/20 (45%)
leucine-rich repeat 107..130 CDD:275380 10/50 (20%)
LRR 4 130..151 10/20 (50%)
leucine-rich repeat 131..154 CDD:275380 11/22 (50%)
LRR 5 154..175 6/20 (30%)
leucine-rich repeat 155..178 CDD:275380 8/22 (36%)
LRR 6 178..199 4/20 (20%)
leucine-rich repeat 179..250 CDD:275380 16/72 (22%)
LRR 7 202..223 7/22 (32%)
leucine-rich repeat 203..226 CDD:275380 8/24 (33%)
LRR 8 250..271 5/20 (25%)
leucine-rich repeat 251..274 CDD:275380 5/22 (23%)
LRR 9 274..295 5/20 (25%)
leucine-rich repeat 275..298 CDD:275380 5/22 (23%)
LRR 10 298..319 6/20 (30%)
leucine-rich repeat 299..322 CDD:275380 6/22 (27%)
LRR 11 322..343 4/20 (20%)
leucine-rich repeat 323..343 CDD:275380 4/19 (21%)
Ig 425..500 CDD:386229
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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