DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsynB and atp5pb

DIOPT Version :9

Sequence 1:	NP_524011.1	Gene:	ATPsynB / 39143	FlyBaseID:	FBgn0019644	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_989118.1	Gene:	atp5pb / 394723	XenbaseID:	XB-GENE-972907	Length:	250	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	115/248 - (46%)
Similarity:	159/248 - (64%)	Gaps:	16/248 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFSRAALLTAQ-----RPLTVAATRSAAA------AAAPGGAIERRQRPEHPGKVRLGFLPEEWF 54
            |.|||||.:|.     .||:|.......:      |.||...:     ||..||||.|.:|||:|
Frog     1 MLSRAALTSASALRKTAPLSVGLLNQCRSFHKGQPAMAPVPPL-----PEKGGKVRFGLIPEEFF 60

  Fly    55 QFFYNKTGVTGPYTFGVGLITYLCSKEIYVMEHEYYSGLSLGIMAIIAVKKLGPVIAKWADGEID 119
            ||.|.||||||||..|.||:.||.||||||:.||.::..|:||:.:..:||.||.:|.:||...:
Frog    61 QFLYPKTGVTGPYMLGTGLLVYLLSKEIYVINHETFAAASIGIVIVYGIKKFGPSVAAFADKLNE 125

  Fly   120 KIESEWKEGREAELKVLSDAIEAEKKEQWRADGALLLMEAKKENIALQLEAAFRERAMNVYSEVK 184
            :..::.:..:::.||.|..|||.|.|||||.:|...|.:||:.|:.:.||..:|||.:|||:|||
Frog   126 EKVAKAQAVKDSALKNLERAIEEENKEQWRVEGRHHLFDAKRNNVTMLLEINYRERILNVYNEVK 190

  Fly   185 RRLDYQVECRHVERRLSQKHMVNWITTNVLASISPQQEKETLNKCIADLSALA 237
            :||||||..:|::||..|.||:||:..||:.||:|||:||::.|||.||..|:
Frog   191 KRLDYQVALQHLQRRKEQDHMINWVEKNVIQSITPQQQKESIAKCITDLKVLS 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynB	NP_524011.1	Mt_ATP-synt_B	73..233	CDD:368426	75/159 (47%)
atp5pb	NP_989118.1	Mt_ATP-synt_B	79..240	CDD:368426	76/160 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	165	1.000	Domainoid score	I3884
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1275
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3471
OMA	1	1.010	-	-		QHG52501
OrthoDB	1	1.010	-	-		D1314411at2759
OrthoFinder	1	1.000	-	-		FOG0005510
OrthoInspector	1	1.000	-	-		oto105344
Panther	1	1.100	-	-	LDO	PTHR12733
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3753
SonicParanoid	1	1.000	-	-		X4458
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110