DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsynB and asb-2

DIOPT Version :9

Sequence 1:	NP_524011.1	Gene:	ATPsynB / 39143	FlyBaseID:	FBgn0019644	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_508770.1	Gene:	asb-2 / 180718	WormBaseID:	WBGene00000207	Length:	305	Species:	Caenorhabditis elegans

Alignment Length:	217	Identity:	60/217 - (27%)
Similarity:	104/217 - (47%)	Gaps:	24/217 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RPEHPGKVRLGFLPEEWFQFFYNKTGVTGPYTFGVGLITYLCSKEIYVMEHEYYSGLSLGIMAII 101
            ||.:|.|.||..:|:.||..|...|||:|||.|..||..:|.:||::|.|.:.:..:...:..::
Worm   100 RPMYPPKSRLLMMPDSWFTPFQKVTGVSGPYLFFGGLFAFLVNKELWVFEEQGHMTVGWILFYLL 164

  Fly   102 AVKKLGPVIAKWADGEIDKIESEWKEGREAELKV--------LSDAIEAEKKEQWRADGALLLME 158
            ..:..|           .||:.....|.:..:..        |.:|:|.:|....:.:....:.|
Worm   165 VTRTAG-----------YKIDQGLYNGYQERVNFFKGLIQEDLKEAVEFKKTSAKQTESLNSIKE 218

  Fly   159 ----AKKENIALQLEAAFRERAMNVYSEVKRRLDYQVECRHVERRLSQKHMVNWITTNVLASISP 219
                |.||::||||||.:|:...:|.:|:|||:||..|....:.|:.::.::..|.:.|....|.
Worm   219 SYPTALKESMALQLEATYRKNVQSVATELKRRIDYLKETEESKARVEREQLLKLINSEVDKEFSD 283

  Fly   220 QQEKET-LNKCIADLSALALRV 240
            :..|:. |...|..|..|.:::
Worm   284 RSFKDKYLQNAIQQLKGLNVQL 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynB	NP_524011.1	Mt_ATP-synt_B	73..233	CDD:368426	40/172 (23%)
asb-2	NP_508770.1	Mt_ATP-synt_B	136..299	CDD:283144	40/173 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160746
Domainoid	1	1.000	52	1.000	Domainoid score	I7681
eggNOG	1	0.900	-	-		E1_KOG3976
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I3686
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52501
OrthoDB	1	1.010	-	-		D1314411at2759
OrthoFinder	1	1.000	-	-		FOG0005510
OrthoInspector	1	1.000	-	-		otm14218
orthoMCL	1	0.900	-	-		OOG6_106091
Panther	1	1.100	-	-	LDO	PTHR12733
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3753
SonicParanoid	1	1.000	-	-		X4458
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.840