DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsynB and asb-1

DIOPT Version :9

Sequence 1:	NP_524011.1	Gene:	ATPsynB / 39143	FlyBaseID:	FBgn0019644	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_497938.1	Gene:	asb-1 / 175605	WormBaseID:	WBGene00000206	Length:	301	Species:	Caenorhabditis elegans

Alignment Length:	212	Identity:	60/212 - (28%)
Similarity:	103/212 - (48%)	Gaps:	18/212 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RPEHPGKVRLGFLPEEWFQFFYNKTGVTGPYTFGVGLITYLCSKEIYVMEHEYYSGLSLGIMAII 101
            ||.:|.|.||..:|:.||..|...||.:|||.|..||..:|.:||::|.|.:.:..:...:..::
Worm    98 RPMYPPKTRLLMMPDSWFTAFQKVTGTSGPYLFFGGLFAFLVNKELWVFEEQGHMTVGWILFYLL 162

  Fly   102 AVKKLGPVIAKWADGEIDKIESE----WKEGREAELKVLSDAIEAEKKEQWRADGALLLME---- 158
            ..:..|..|    |..:.|...|    :|...:.:||   :|::..|....:......|.|
Worm   163 VSRTAGYKI----DAGLYKDYQERVGFFKGLIQEDLK---EAVDFRKTSAAQTASFAALKEGMPT 220

  Fly   159 AKKENIALQLEAAFRERAMNVYSEVKRRLDYQVECRHVERRLSQKHMVNWITTNVLASISPQ--Q 221
            :.|:::.||||||:|:....:.:|:|||::|..|....:.|..:..::..|..:|...:|.:  |
Worm   221 SLKDSMQLQLEAAYRKNVQTISNEIKRRIEYLKETEETKARFERDQLLKLINDSVEKQVSQKDFQ 285

  Fly   222 EKETLNKCIADLSALAL 238
            || .|...|..|..:|:
Worm   286 EK-FLQNAIQQLKGIAV 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynB	NP_524011.1	Mt_ATP-synt_B	73..233	CDD:368426	41/169 (24%)
asb-1	NP_497938.1	Mt_ATP-synt_B	134..297	CDD:283144	41/170 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160747
Domainoid	1	1.000	52	1.000	Domainoid score	I7681
eggNOG	1	0.900	-	-		E1_KOG3976
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I3686
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52501
OrthoDB	1	1.010	-	-		D1314411at2759
OrthoFinder	1	1.000	-	-		FOG0005510
OrthoInspector	1	1.000	-	-		otm14218
orthoMCL	1	0.900	-	-		OOG6_106091
Panther	1	1.100	-	-	O	PTHR12733
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3753
SonicParanoid	1	1.000	-	-		X4458
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.840