DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsynB and Atp5pb

DIOPT Version :9

Sequence 1:	NP_524011.1	Gene:	ATPsynB / 39143	FlyBaseID:	FBgn0019644	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_599192.1	Gene:	Atp5pb / 171375	RGDID:	620041	Length:	256	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	106/269 - (39%)
Similarity:	144/269 - (53%)	Gaps:	44/269 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFSRAALLTAQRPLTVAATRSAAAAAAP--------GGAIERRQR---------------PEHPG 42
            |.||..|             ||||.|||        |..:.:..|               ||:.|
  Rat     1 MLSRVVL-------------SAAATAAPCLKNAAVLGPGVLQATRVFHTGQPRLAPLPPLPEYGG 52

  Fly    43 KVRLGFLPEEWFQFFYNKTGVTGPYTFGVGLITYLCSKEIYVMEHEYYSGLSLGIMAIIAVKKLG 107
            |||||.:|||:|||.|.||||||||..|.||..|..||||||:..|.:|.:|:..:.:..:||.|
  Rat    53 KVRLGLIPEEFFQFLYPKTGVTGPYVLGTGLSLYFLSKEIYVITPETFSTISVVGLIVYVIKKYG 117

  Fly   108 PVIAKWADGEIDKIESE----WKEGREAELKVLSDAIEAEKKEQWRADGALLLMEAKKENIALQL 168
            ..|.::    |||:..|    .:|.:::.:|.:.|||..||.:|........|.:.::.||||.|
  Rat   118 ASIGEF----IDKLNEEKIAQLEEIKQSSMKQIQDAINREKAQQALVQKRHYLFDVQRNNIALAL 178

  Fly   169 EAAFRERAMNVYSEVKRRLDYQVECRHVERRLSQKHMVNWITTNVLASISPQQEKETLNKCIADL 233
            |..:|||....|.|||.||||.:..:.:.||...:||:||:..:|:.|||.||||||:.|||.||
  Rat   179 EVTYRERLHKAYKEVKNRLDYHISVQDMMRRKEGEHMINWVEKHVIQSISAQQEKETIAKCIGDL 243

  Fly   234 SALALRVKS 242
            ..||.:.::
  Rat   244 KMLAKKAQA 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynB	NP_524011.1	Mt_ATP-synt_B	73..233	CDD:368426	64/163 (39%)
Atp5pb	NP_599192.1	Mt_ATP-synt_B	83..244	CDD:283144	65/164 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343262
Domainoid	1	1.000	121	1.000	Domainoid score	I5597
eggNOG	1	0.900	-	-		E1_KOG3976
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1275
Inparanoid	1	1.050	178	1.000	Inparanoid score	I3917
OMA	1	1.010	-	-		QHG52501
OrthoDB	1	1.010	-	-		D1314411at2759
OrthoFinder	1	1.000	-	-		FOG0005510
OrthoInspector	1	1.000	-	-		oto98649
orthoMCL	1	0.900	-	-		OOG6_106091
Panther	1	1.100	-	-	LDO	PTHR12733
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4458
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810