DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsynB and Atp5pb

DIOPT Version :9

Sequence 1:	NP_524011.1	Gene:	ATPsynB / 39143	FlyBaseID:	FBgn0019644	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_033855.2	Gene:	Atp5pb / 11950	MGIID:	1100495	Length:	256	Species:	Mus musculus

Alignment Length:	259	Identity:	104/259 - (40%)
Similarity:	144/259 - (55%)	Gaps:	24/259 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFSRAALLTAQRPLTVAATRSAAAAAAPGGAIERR-------------QRPEHPGKVRLGFLPEE 52
            |.||..|..|   .|.|.....|||..||.....|             ..||:.||||||.:|||
Mouse     1 MLSRVVLSAA---ATAAPCLKNAAALGPGVLQATRAFHTGQPRLAPLPPLPEYGGKVRLGLIPEE 62

  Fly    53 WFQFFYNKTGVTGPYTFGVGLITYLCSKEIYVMEHEYYSGLSLGIMAIIAVKKLGPVIAKWADGE 117
            :|||.|.||||||||..|.||..|..||||||:..|.:|.:|:..:.:..:||.|....::
Mouse    63 FFQFLYPKTGVTGPYVLGTGLSLYFLSKEIYVITPETFSTISVVGLIVYVIKKYGASFGEF---- 123

  Fly   118 IDKIESE----WKEGREAELKVLSDAIEAEKKEQWRADGALLLMEAKKENIALQLEAAFRERAMN 178
            |||:..|    .:|.:::.:|.:.|||:.||.:|........|.:.::.||||.||..:|||...
Mouse   124 IDKLNEEKIAQLEEVKQSSMKQIQDAIDMEKAQQALVQKRHYLFDVQRNNIALALEVTYRERLHK 188

  Fly   179 VYSEVKRRLDYQVECRHVERRLSQKHMVNWITTNVLASISPQQEKETLNKCIADLSALALRVKS 242
            .|.|||.||||.:..:::.||..::||::|:..:|:.|||.||||||:.|||.||..||.:.::
Mouse   189 AYKEVKNRLDYHISVQNMMRRKEEEHMIDWVEKHVVKSISVQQEKETIAKCIEDLKLLAKKAQA 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynB	NP_524011.1	Mt_ATP-synt_B	73..233	CDD:368426	62/163 (38%)
Atp5pb	NP_033855.2	Mt_ATP-synt_B	83..244	CDD:368426	63/164 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839445
Domainoid	1	1.000	119	1.000	Domainoid score	I5798
eggNOG	1	0.900	-	-		E1_KOG3976
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1275
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4012
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52501
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005510
OrthoInspector	1	1.000	-	-		oto95160
orthoMCL	1	0.900	-	-		OOG6_106091
Panther	1	1.100	-	-	LDO	PTHR12733
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3753
SonicParanoid	1	1.000	-	-		X4458
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790