DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Naa60 and NAA11

DIOPT Version :9

Sequence 1:	NP_996032.1	Gene:	Naa60 / 39142	FlyBaseID:	FBgn0036039	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_116082.1	Gene:	NAA11 / 84779	HGNCID:	28125	Length:	229	Species:	Homo sapiens

Alignment Length:	188	Identity:	46/188 - (24%)
Similarity:	74/188 - (39%)	Gaps:	47/188 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 VQLRFLVPDDLTEVRQ---LCQEWFPIDYPLSWYEDITSSTRFFALAAVYNLAIIGLIVAEIKPY 95
            :.:|...||||..::.   ||   .|.:|.:.:|              :|:    ||...::
Human     1 MNIRNAQPDDLMNMQHCNLLC---LPENYQMKYY--------------LYH----GLSWPQL--- 41

  Fly    96 RNVNKEVIANMSDSDELYTRLSGFPMQDKGILPDSMGRSADVGYILSLGVHRSHRRNGIGSLLLD 160
                 ..||...|.     ::.|:.:......||.:..    |:|.||.|.|||||.|:...|:|
Human    42 -----SYIAEDEDG-----KIVGYVLAKMEEEPDDVPH----GHITSLAVKRSHRRLGLAQKLMD 92

  Fly   161 ALMNHLTTAERHSVKAIFLHTLTTNQPAIFFYEKR-RFTLHSFLPYYYNIRGKGKDGF 217
            .....:  .|..:.|.:.||...:|:||:..|... .|.:....|.||   ..|:|.:
Human    93 QASRAM--IENFNAKYVSLHVRKSNRPALHLYSNTLNFQISEVEPKYY---ADGEDAY 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naa60	NP_996032.1	RimI	74..207	CDD:223532	32/133 (24%)
Naa60	NP_996032.1	Acetyltransf_1	<136..198	CDD:278980	21/62 (34%)
NAA11	NP_116082.1	RimI	1..149	CDD:223532	46/188 (24%)
		Interaction with NAA15. /evidence=ECO:0000250	1..58		17/90 (19%)
		Acetyltransf_1	47..122	CDD:278980	24/85 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	175..229
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0456
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810