DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Naa60 and NAA60

DIOPT Version :9

Sequence 1:	NP_996032.1	Gene:	Naa60 / 39142	FlyBaseID:	FBgn0036039	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_001304022.1	Gene:	NAA60 / 79903	HGNCID:	25875	Length:	249	Species:	Homo sapiens

Alignment Length:	215	Identity:	103/215 - (47%)
Similarity:	131/215 - (60%)	Gaps:	27/215 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 DYPLSWYEDITSSTRFFALAAVYNLAIIGLIVAEIKPYRNVNKEVIANMSDSDELYTRLSGFPMQ 122
            :||.|||.||||:.:||:|||.|..||:|:||||||....::||
Human    44 EYPDSWYRDITSNKKFFSLAATYRGAIVGMIVAEIKNRTKIHKE--------------------- 87

  Fly   123 DKGILPDSMGRSADVGYILSLGVHRSHRRNGIGSLLLDALMNHLTTAERHSVKAIFLHTLTTNQP 187
            |..||..:......|.|||||||.:..|::|||||||::|.:|::|..:...|||:||.||||..
Human    88 DGDILASNFSVDTQVAYILSLGVVKEFRKHGIGSLLLESLKDHISTTAQDHCKAIYLHVLTTNNT 152

  Fly   188 AIFFYEKRRFTLHSFLPYYYNIRGKGKDGFTYVNYINGGHPPWTLLDHIKHYASMVRHTSSLCAW 252
            ||.|||.|.|..|.:|||||:|||..|||||||.||||||||||:||:|:|..|.:...|. |:
Human   153 AINFYENRDFKQHHYLPYYYSIRGVLKDGFTYVLYINGGHPPWTILDYIQHLGSALASLSP-CS- 215

  Fly   253 LAGRVQQVVRWFYHKLLTRF 272
            :..||.:..    |.||..|
Human   216 IPHRVYRQA----HSLLCSF 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naa60	NP_996032.1	RimI	74..207	CDD:223532	58/132 (44%)
Naa60	NP_996032.1	Acetyltransf_1	<136..198	CDD:278980	34/61 (56%)
NAA60	NP_001304022.1	RimI	<44..173	CDD:223532	69/149 (46%)
NAA60	NP_001304022.1	Acetyltransf_1	86..163	CDD:278980	39/97 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147265
Domainoid	1	1.000	115	1.000	Domainoid score	I6047
eggNOG	1	0.900	-	-		E1_COG0456
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32610
Inparanoid	1	1.050	220	1.000	Inparanoid score	I3571
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58755
OrthoDB	1	1.010	-	-		D1619974at2759
OrthoFinder	1	1.000	-	-		FOG0005438
OrthoInspector	1	1.000	-	-		oto91782
orthoMCL	1	0.900	-	-		OOG6_104382
Panther	1	1.100	-	-	LDO	PTHR14744
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2980
SonicParanoid	1	1.000	-	-		X5008
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800