DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Naa60 and KAT14

DIOPT Version :9

Sequence 1:	NP_996032.1	Gene:	Naa60 / 39142	FlyBaseID:	FBgn0036039	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_001371121.2	Gene:	KAT14 / 57325	HGNCID:	15904	Length:	782	Species:	Homo sapiens

Alignment Length:	176	Identity:	37/176 - (21%)
Similarity:	63/176 - (35%)	Gaps:	60/176 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 FLVPDDLTEVRQLCQEWFPIDYPLS---WYEDITSSTRFFALAAVYNLAII--GLIVAEIKPYRN 97
            ::.|:.:..:..:|||:|.....||   .|.|       |::..:|...||  |.:|.::|
Human   642 YVRPNHIPTINSMCQEFFWPGIDLSECLQYPD-------FSVVVLYKKVIIAFGFMVPDVK---- 695

  Fly    98 VNKEVIANMSDSDELYTRLSGFPMQDKGILPDSMGRSADVGYILSLGVHRSHRRNGIGSLLLDAL 162
                           |..                      .||..|.||...||.||.:.::..|
Human   696 ---------------YNE----------------------AYISFLFVHPEWRRAGIATFMIYHL 723

  Fly   163 MNHLTTAERHSVKAIFLHTLTTNQPAIFFYEKRRFTLHSFLPYYYN 208
            :      :....|.:.||...:| ||:..|:|..|....::..:|:
Human   724 I------QTCMGKDVTLHVSASN-PAMLLYQKFGFKTEEYVLDFYD 762

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naa60	NP_996032.1	RimI	74..207	CDD:223532	27/134 (20%)
Naa60	NP_996032.1	Acetyltransf_1	<136..198	CDD:278980	18/61 (30%)
KAT14	NP_001371121.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	13..33
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	251..282
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	315..346
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	400..460
		Acetyltransf_1	<672..751	CDD:395465	27/133 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0456
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810