DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Naa60 and naa60

DIOPT Version :9

Sequence 1:	NP_996032.1	Gene:	Naa60 / 39142	FlyBaseID:	FBgn0036039	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_001106444.1	Gene:	naa60 / 100127619	XenbaseID:	XB-GENE-941561	Length:	242	Species:	Xenopus tropicalis

Alignment Length:	240	Identity:	108/240 - (45%)
Similarity:	143/240 - (59%)	Gaps:	38/240 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SINDVQLRFLVPDDLTEVRQLCQEWFPIDYPLSWYEDITSSTRFFALAAVYNLAIIGLIVAEIKP 94
            ::.|..||||..||:..|::||.:||||:||.|||.||||:.:||:|||.||..|:|:||||||.
Frog     9 ALADTILRFLCHDDIDTVKELCADWFPIEYPDSWYRDITSNKKFFSLAATYNGQIVGMIVAEIKG 73

  Fly    95 YRNVNKEVIANMSDSDELYTRLSGFPMQDKGILPDSMGRSADVGYILSLGVHRSHRRNGIGSLLL 159
            ...|:||                     |..||..|......|.|||||||.:..|:.|||||||
Frog    74 RTKVHKE---------------------DGDILASSFSGDTQVAYILSLGVVKEFRKQGIGSLLL 117

  Fly   160 DALMNHLTTAERHSVKAIFLHTLTTNQPAIFFYEKRRFTLHSFLPYYYNIRGKGKDGFTYVNYIN 224
            ::|.:|:::..:...||::||.||||..||.|||.|.|..|.:|||||:|||..:|.:|||.|:|
Frog   118 ESLKSHISSTAQDHCKALYLHVLTTNSNAIRFYENRHFHQHHYLPYYYSIRGVLQDAYTYVLYLN 182

  Fly   225 GGHPPWTLLDHIKHYASMV---------------RHT--SSLCAW 252
            |||||||::|:::|..|.:               .||  .||..|
Frog   183 GGHPPWTVMDYLQHLGSALAGFSPCTLPQRIYRQAHTLLRSLLPW 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naa60	NP_996032.1	RimI	74..207	CDD:223532	58/132 (44%)
Naa60	NP_996032.1	Acetyltransf_1	<136..198	CDD:278980	32/61 (52%)
naa60	NP_001106444.1	Acetyltransf_1	23..155	CDD:366181	70/152 (46%)
		Acetyl-CoA binding. /evidence=ECO:0000250\|UniProtKB:Q9H7X0	101..103		1/1 (100%)
		Acetyl-CoA binding. /evidence=ECO:0000250\|UniProtKB:Q9H7X0	109..114		2/4 (50%)
		Acetyl-CoA binding. /evidence=ECO:0000250\|UniProtKB:Q9H7X0	150..153		2/2 (100%)
		Required for homodimerization. /evidence=ECO:0000250\|UniProtKB:Q9H7X0	162..173		7/10 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	114	1.000	Domainoid score	I6039
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32610
Inparanoid	1	1.050	209	1.000	Inparanoid score	I3588
OMA	1	1.010	-	-		QHG58755
OrthoDB	1	1.010	-	-		D1619974at2759
OrthoFinder	1	1.000	-	-		FOG0005438
OrthoInspector	1	1.000	-	-		oto105537
Panther	1	1.100	-	-	LDO	PTHR14744
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2980
SonicParanoid	1	1.000	-	-		X5008
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110