Protein Alignment defl and Ints7

DIOPT Version :10

• Sequence 1: NP_648352.2
• Gene: defl / 39141
• FlyBaseID: FBgn0036038
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: NP_001178604.1
• Gene: Ints7 / 289382
• RGDID: 1308014
• Length: 967
• Species: Rattus norvegicus
• Alignment Length: 1014
• Identity: 360/1014 - (35%)
• Similarity: 539/1014 - (53%)
• Gaps: 118/1014 - (11%)

  Fly    10 STFNESFL-----NENEHDSNAVLMELDKGLRSTKQGIQCEAVVRFPRLFEKYPFPILINSSFIK 69
            |...:|||     .|.|.|:|:.||||||||||.|.|.||||||||||||:||||||||||:|:|
  Rat     3 SNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLK 67

  Fly    70 LADYFVSGSNLLRFWVLRVCQQSENHLDKILNIDSFVRCIFVVMHSNDPVARALLLRTLGAVSRV 134
            |||.|..|:|.||..||:|.||||.||:||||:|.||:.:|.|:|||||||||:.||.||:::.:
  Rat    68 LADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRVFSVIHSNDPVARAITLRMLGSLASI 132

  Fly   135 IPEKQQVHHAIRRALDSHDTVEVEAAIYASSCFAAQSSSFAISMCAKISDMIESLQVPVPMKLLL 199
            |||::..||:||::|||||.||||||::|::.|:|||..||:.:|.|||:||:.|..||.:||.|
  Rat   133 IPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKL 197

  Fly   200 IPVLRHMHHEATTASLVSRLCMDLLPKYPAQSFVVAIIDTLTQLSSRTLVGVPGQLDVLLDFMQ- 263
            ||:|:||||:|..||...:|...|:..||:...|:..:.|.|.|::.:||..|.|:.:||.:::
  Rat   198 IPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKS 262

  Fly   264 DLRTPVRIQVLRSFNELAGRQSVHAWPKPAIKALIDRFELCTNSKEQFLFLSILLKLSECPLTCQ 328
            |.|..|:...::....||.: :.|.|.|..|:||.   |...::....|.|.:|..||....|
  Rat   263 DPRKAVKRLAVQDLKLLASK-TPHTWSKENIQALC---ECALHTPYDSLKLGMLSVLSTLSGT-- 321

  Fly   329 QLLREHRVA--------------LLRLCIQCISKLDDYTTATQAMAVLSVLVAFGLKKKGSGEQV 379
             :..:|..:              |::|..:|....:....|.....:.::.|:...|...|.||
  Rat   322 -IAIKHYFSVAPGNVGSSPRSSDLVKLAQECCYHSNRAIAAHGVRVLTNITVSCQEKDLLSLEQ- 384

  Fly   380 DDILHMVNLHMEGLLLCTAKRSECTRD-LRRVLTYGIRITKANAEFGTSFIGIVTNSLGDKGAYP 443
            |.:..:.:|    |:||:...|...:. ::..|:..:::.|.......|.:..:...|...   .
  Rat   385 DAVFGLESL----LVLCSQDDSPGAQSTVKSALSCMVKLAKGRPHLSRSVVDTLLTQLHSS---Q 442

  Fly   444 PANAELMCEALAGLCEHFQLRKYAFSTAEDLIVDENAMDTDELPPPKINPMLARLPLI------- 501
            .|...|||..||.:                      ||               :||::
  Rat   443 DAARILMCHCLAAI----------------------AM---------------KLPVLGDGMLGD 470

  Fly   502 LHKLNTIIDQENCDQQLRSVEILSSLVL---QTTMGCYLPQKVVQCFEKCLGRLNCWTLYRIART 563
            |.:|..:|.:...|:|...:..|::::.   |..:...:...:.|..|..   .:.||:|||||.
  Rat   471 LVELYKVIGRSATDKQQELLVSLATVIFVASQKALSAEVKAVIKQQLESV---SSGWTVYRIARQ 532

  Fly   564 ASRYGHHYVAAHIYTKVSQIVISDHMHYFLVALSQISQAECILNYGLEYAYMRDNYAPKVAPEPL 628
            |||.|:|.:|..:|..:...|.|:|.:::|.:|.:.|.||..|. ||:....  :.|.....|.|
  Rat   533 ASRMGNHDMARELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLT-GLQEGSF--SSALSCIAESL 594

  Fly   629 IPLMKRLEMASNLYQQALASLRAGSSPQHPCTFQLEYLKIRAQFLQTLHLAVTVKNAQVIVPPPA 693
                       ..|.:.:|||.|.|:|.:|.:||.|::|:|...||.....:...|:....||||
  Rat   595 -----------KFYHKGIASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPA 648

  Fly   694 IAGSLAQNSRDYLQKFGHVTNQLRKLVKALKACEETYARLYKSSFDADHVTLEFLEVAEFQCALF 758
            ||.::|....:.||:.|.::||:::.::..::....|..||::|||||..||..:|:.:..|.|.
  Rat   649 IATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYRDLYQASFDADSATLRNVELQQQSCLLI 713

  Fly   759 AHIIESICYATPPEPPVFLTTGD----HPETRYFAASCQRMEQMQKNLPQ--EPANAK--TISNR 815
            ||.||::  ...||...|...|.    |.::.|.    :||..:..::.:  |..|.|  .:|..
  Rat   714 AHAIEAL--VLDPESASFQEYGSTGAAHADSEYE----RRMMSVYSHVLEEVESLNRKYAPVSYM 772

  Fly   816 HLDVIIAQIEIITKTPLCLPRYFFQILQSTQIKLSVSPQPRSATEPVNVQSGSNLVIKVEGVLQH 880
            |...:...|..:.|.||...|||||.||||.|||::||.||:..||:.||:...|.:|||||:||
  Rat   773 HTACLCNAIIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQH 837

  Fly   881 FSKQKKHFRRVESVQLSLTSQLITPPPRSSQELPKQGANDTVTLNQIVKPQRDFLSGSFLLPISN 945
            .||... |||::||.|:::|.|   ..:|||:......:.|..:.|.|:|..|:.|..|||..:.
  Rat   838 GSKPGL-FRRIQSVCLNVSSTL---QSKSSQDYKIPVDSMTNEMEQRVEPHNDYFSTQFLLNFAV 898

  Fly   946 GGHFQVTLETFVVDENGITWCTGPKSSMVVRVLEDPSKQ 984
            .|...:|:|:.|.|.|||.|.|||:::|.|:.||||..|
  Rat   899 LGTHSITVESSVRDANGIVWKTGPRTTMFVKSLEDPYSQ 937