Protein Alignment defl and INTS7

DIOPT Version :9

• Sequence 1: NP_648352.2
• Gene: defl / 39141
• FlyBaseID: FBgn0036038
• Length: 1001
• Species: Drosophila melanogaster
• Sequence 2: XP_011507698.1
• Gene: INTS7 / 25896
• HGNCID: 24484
• Length: 998
• Species: Homo sapiens
• Alignment Length: 1063
• Identity: 363/1063 - (34%)
• Similarity: 539/1063 - (50%)
• Gaps: 180/1063 - (16%)

  Fly    10 STFNESFL-----NENEHDSNAVLMELDKGLRSTKQGIQCEAVVRFPRLFEKYPFPILINSSFIK 69
            |...:|||     .|.|.|:|:.||||||||||.|.|.||||||||||||:||||||||||:|:|
Human     3 SNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLK 67

  Fly    70 LADYFVSGSNLLRFWVLRVCQQSENHLDKILNIDSFVRCIFVVMHSNDPVARALLLRTLGAVSRV 134
            |||.|..|:|.||..||:|.||||.||:||||:|.||:.||.|:|||||||||:.||.||:::.:
Human    68 LADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRIFSVIHSNDPVARAITLRMLGSLASI 132

  Fly   135 IPEKQQVHHAIRRALDSHDTVEVEAAIYASSCFAAQSSSFAISMCAKISDMIESLQVPVPMKLLL 199
            |||::..||:||::|||||.||||||::|::.|:|||..||:.:|.|||:||:.|..||.:||.|
Human   133 IPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKL 197

  Fly   200 IPVLRHMHHEATTASLVSRLCMDLLPKYPAQSFVVAIIDTLTQLSSRTLVGVPGQLDVLLDFMQ- 263
            ||:|:||||:|..||...:|...|:..||:...|:..:.|.|.|::.:||..|.|:.:||.:::
Human   198 IPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKN 262

  Fly   264 DLRTPVRIQVLRSFNELAGRQSVHAWPKPAIKALIDRFELCTNSKEQFLFLSILLKLSECPLTCQ 328
            |.|..|:...::....||.: :.|.|.:..|:||.   |....:....|.|.:|..||....|
Human   263 DPRKAVKRLAIQDLKLLANK-TPHTWSRENIQALC---ECALQTPYDSLKLGMLSVLSTLSGT-- 321

  Fly   329 QLLREHRVA--------------LLRLCIQC------------ISKLDDYTTATQAMAVLSVLVA 367
             :..:|..:              |::|..:|            :..|.:.|.:.|...:|::
Human   322 -IAIKHYFSIVPGNVSSSPRSSDLVKLAQECCYHNNRGIAAHGVRVLTNITVSCQEKDLLAL--- 382

  Fly   368 FGLKKKGSGEQVDDILHMVNLHMEGLLLCTAKRSE-CTRDLRRVLTYGIRITKANAEFGTSFIGI 431
                     || |.:..:.:|    |:||:...|. ....|:..|...:::.|.......|   :
Human   383 ---------EQ-DAVFGLESL----LVLCSQDDSPGAQATLKIALNCMVKLAKGRPHLSQS---V 430

  Fly   432 VTNSLGDKGAYPPANAELMCEALAGLCEHFQLRKYAFSTAEDL-----IVDENAMDTDELPPPKI 491
            |...|....:...|...|||..||.:.  .||.........||     ::..:|.|       |.
Human   431 VETLLTQLHSAQDAARILMCHCLAAIA--MQLPVLGDGMLGDLMELYKVIGRSATD-------KQ 486

  Fly   492 NPMLARLPLIL----HKLNTIIDQENCDQQLRSVEILSSLVLQTTMGCYLPQKVVQCFEKCLGRL 552
            ..:|..|..::    .|..::..:....|||.||.
Human   487 QELLVSLATVIFVASQKALSVESKAVIKQQLESVS------------------------------ 521

  Fly   553 NCWTLYRIARTASRYGHHYVAAHIYTKVSQIVISDHMHYFLVALSQISQAECILNYGLEYAYMRD 617
            |.||:|||||.|||.|:|.:|..:|..:...|.|:|.:::|.:|.:.|.||..|. ||:    .:
Human   522 NGWTVYRIARQASRMGNHDMAKELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLT-GLQ----EE 581

  Fly   618 NYAPKVA--PEPLIPLMKRLEMASNLYQQALASLRAGSSPQHPCTFQLEYLKIRAQFLQTLHLAV 680
            ||:..::  .|.|           ..|.:.:|||.|.|:|.:|.:||.|::|:|...||.....:
Human   582 NYSSALSCIAESL-----------KFYHKGIASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLI 635

  Fly   681 TVKNAQVIVPPPAIAGSLAQNSRDYLQKFGHVTNQLRKLVKALKACEETYARLYKSSFDADHVTL 745
            ...|:....||||||.::|....:.||:.|.::||:::.::..::....|..||::|||||..||
Human   636 CTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYGDLYQASFDADSATL 700

  Fly   746 EFLEVAEFQCALFAHIIESICYATPPEPPVFLTTGD----HPETRYF------------------ 788
            ..:|:.:..|.|.:|.||::  ...||...|...|.    |.::.|.
Human   701 RNVELQQQSCLLISHAIEAL--ILDPESASFQEYGSTGTAHADSEYERRMMSVYNHVLEEVESLN 763

  Fly   789 ----------------AASCQRMEQMQKNLPQEPANAKTISNRHL------DVIIAQIEIITKTP 831
                            .:|||::..:.:........|..:.:.|:      :.|||    :.|.|
Human   764 RKYTPVSYMFWRQESPVSSCQQIRFLVRTFFLALVTATFLLHLHMHTACLCNAIIA----LLKVP 824

  Fly   832 LCLPRYFFQILQSTQIKLSVSPQPRSATEPVNVQSGSNLVIKVEGVLQHFSKQKKHFRRVESVQL 896
            |...|||||.||||.|||::||.||:..||:.||:...|.:|||||:||.||... ||:::||.|
Human   825 LSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPGL-FRKIQSVCL 888

  Fly   897 SLTSQLITPPPRSSQELPKQGANDTVTLNQIVKPQRDFLSGSFLLPISNGGHFQVTLETFVVDEN 961
            :::|.|   ..:|.|:......|.|..:.|.|:|..|:.|..|||..:..|...:|:|:.|.|.|
Human   889 NVSSTL---QSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFAILGTHNITVESSVKDAN 950

  Fly   962 GITWCTGPKSSMVVRVLEDPSKQ 984
            ||.|.|||::::.|:.||||..|
Human   951 GIVWKTGPRTTIFVKSLEDPYSQ 973

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147595
Domainoid	1	1.000	517	1.000	Domainoid score	I308
eggNOG	1	0.900	-	-		E1_KOG1988
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9136
Inparanoid	1	1.050	519	1.000	Inparanoid score	I1280
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45867
OrthoDB	1	1.010	-	-		D1131967at2759
OrthoFinder	1	1.000	-	-		FOG0005715
OrthoInspector	1	1.000	-	-		oto90203
orthoMCL	1	0.900	-	-		OOG6_105240
Panther	1	1.100	-	-	LDO	PTHR13322
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3209
SonicParanoid	1	1.000	-	-		X5418
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800