Protein Alignment vsg and CD164

DIOPT Version :9

• Sequence 1: NP_001261646.1
• Gene: vsg / 39137
• FlyBaseID: FBgn0045823
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_006007.2
• Gene: CD164 / 8763
• HGNCID: 1632
• Length: 197
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 69/226 - (30%)
• Similarity: 93/226 - (41%)
• Gaps: 73/226 - (32%)

  Fly     1 MNRQAKFLI---LCLFVGLFSANLCEEVTTPAPADTTTQESKNTTTPPDTTTTVTPPSTSTTSTT 62
            |:|.::.|:   .||.|      ||           .....||||..|: .||:.|.|    :.|
Human     1 MSRLSRSLLWAATCLGV------LC-----------VLSADKNTTQHPN-VTTLAPIS----NVT 43

  Fly    63 TEKTTTTPPITTSTEKT-----------------TT------------------------STTPA 86
            :...|:.|.:||...:|                 ||                        :||..
Human    44 SAPVTSLPLVTTPAPETCEGRNSCVSCFNVSVVNTTCFWIECKDESYCSHNSTVSDCQVGNTTDF 108

  Fly    87 STTSSTTPASTTSSTTPATTTTTPGTTSTTTPSPNSTTTTPPPHTSTTPAPKPVPCGHFDGSSFI 151
            .:.|:.||..|.:||...|...:|.|||.|..:..:|..|      .||..:||....||.:|||
Human   109 CSVSTATPVPTANSTAKPTVQPSPSTTSKTVTTSGTTNNT------VTPTSQPVRKSTFDAASFI 167

  Fly   152 GGIVLTLGLLAIGLVAYKFYKARNERNYHTL 182
            |||||.||:.|:....|||.|:: |||||||
Human   168 GGIVLVLGVQAVIFFLYKFCKSK-ERNYHTL 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vsg	NP_001261646.1	MGC-24	<145..182	CDD:283050	22/36 (61%)
CD164	NP_006007.2	MGC-24	60..197	CDD:283050	45/143 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..154		13/41 (32%)
		Required for endosomal and lysosomal localization. /evidence=ECO:0000250	191..197		5/5 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147806
Domainoid	1	1.000	77	1.000	Domainoid score	I8922
eggNOG	1	0.900	-	-		E1_2CF8S
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0009084
OrthoInspector	1	1.000	-	-		oto91335
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11337
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5635
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.960