back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SH3PX1 and snx2

DIOPT Version :10

Sequence 1:	NP_648348.1	Gene:	SH3PX1 / 39136	FlyBaseID:	FBgn0040475	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	NP_001032787.1	Gene:	snx2 / 568737	ZFINID:	ZDB-GENE-051120-45	Length:	506	Species:	Danio rerio

Alignment Length:	553	Identity:	108/553 - (19%)
Similarity:	197/553 - (35%)	Gaps:	132/553 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 EVMSAAEAQKLSASGATSVPQVPDPFASPPL--PRYDQTADDDGSNWDDEDDWSDDNDTYSEIGP 120
            |...|||...:|...:.....||...||...  |:.:|...||    |.||.:::..:..|...|
Zfish    19 EDSEAAEELFVSVMESPEDLHVPSEVASTGSNGPKAEQILLDD----DTEDLFAEATEEVSLDSP 79

  Fly   121 GGQKSAGQSARAGGLSHSTSDYDNKHLPIAPNDDTQSLASVAGGTGAAGTVKKGMFAKSSDSYIL 185
            ..|                        ||..:..:.::..|. .......|:.|.|.:|
Zfish    80 ERQ------------------------PILSDGPSPAITPVT-PVSIGSRVELGAFDRS------ 113

  Fly   186 GLSSTKEKIPECEMAYITQVEDSIYQWTQNHSPYSVVVASPKKESKFKGMKTFIAYQLTP----- 245
                     ||         ||...|.:::.....:.|:.|:|..  .||..::.|::|.
Zfish   114 ---------PE---------EDEDEQESRDTLDIQISVSDPEKVG--DGMNAYMVYKVTTKSCLS 158

  Fly   246 --SFNNISVSRRYKHFDWLHERLVDKFCLIP--VPPLPDKQISGRYE----------EQFVEHRR 296
              |.:.:.|.||:..|..||.:|..|:..:.  |||.|:|.|.|..:          .:|||.||
Zfish   159 VFSRSEVCVRRRFSDFLGLHSKLASKYLHVGLIVPPAPEKSIVGMTKVKVGKEDLSSVEFVEKRR 223

  Fly   297 VQLQEFVDWVCRHPVISKCEVWYHFLTCRD-------EKIWKSGKRKAERDPYMGVNYCLAISPP 354
            ..|:.::....:||.:.|......||...:       :.:..:|..:........||
Zfish   224 SALERYLMRTVKHPALLKDPDVLQFLESSELPRAVSTQALSGAGILRMVNKAADAVN-------- 280

  Fly   355 DKNLLHSKVDAQVELGTQFIHSMDVAVRNLNNISNDMAKRSMSQSKKEFQRIGDGLSDLAKALAI 419
            ...:..::.||..|...|...::|:.:|.|:     .:..|:...:||.. :...|  .||:.|:
Zfish   281 KMTIKMNEADAWFEEKQQQFENLDLQLRKLH-----ASVESLVCHRKELS-VNTAL--FAKSAAM 337

  Fly   420 DERRAPTRNAVPLSESVGRIGGIFIGIGQAFGDQPKHDWIPLSDRLHIYRGVLNCFPDIFSTHKG 484
               ...:.:...||.::.::..:...:.|...||...|:...|:.|..|..::.....:|.....
Zfish   338 ---LGNSEDHTALSRALSQLAEVEEKMDQMHQDQAYADFYLFSELLGDYVRLITAVRGVFDQRMK 399

  Fly   485 AIQKRKDCE-----KLAGEGRM---NNP---------------QLHDVNRRTDVVSYTVLAELTH 526
            ...|.:|.:     |...|.::   |.|               ::....|..:.:|..:..|:..
Zfish   400 TWAKWQDAQVMLQRKREAEAKLQYANKPDKLQQAKDEIKEWEGKVQQGERDFEQISKNIRREVGR 464

  Fly   527 FKSERDTHLKHTLKNFIAEQIKFYQGVVARLQE 559
            |:.:|       :|:|....:|:.:.:|...|:
Zfish   465 FEKDR-------VKDFRIVVVKYLESLVHTQQQ 490

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.