Protein Alignment SH3PX1 and snx18b

DIOPT Version :9

• Sequence 1: NP_648348.1
• Gene: SH3PX1 / 39136
• FlyBaseID: FBgn0040475
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001015063.1
• Gene: snx18b / 548603
• ZFINID: ZDB-GENE-080213-6
• Length: 563
• Species: Danio rerio
• Alignment Length: 605
• Identity: 211/605 - (34%)
• Similarity: 318/605 - (52%)
• Gaps: 94/605 - (15%)

  Fly     1 MTSYVRAMYDFTGE-PGSSELSIATGDVLSVTRSDVGEGWWEGKNARGQIGLFPAAYVEVMSAAE 64
            |....||:||||.| ||  |:|:...:||::...:|.:||.||.|:||:.|||||:|||::....
Zfish     1 MALRARALYDFTSENPG--EISVTENEVLTLCSEEVVDGWLEGTNSRGETGLFPASYVEIIKTDT 63

  Fly    65 AQKLSASGAT------SVPQVPDPF--ASPPLPRYD----------QTADDDGSNWDDEDDWSDD 111
            :...:.:.|:      |.||..|..  ::|....|.          ||:.....:||  ||| ||
Zfish    64 SLHGNGTSASQDYYYQSSPQRRDTSNESTPTHAVYQGHLQQQRLSFQTSQGSDEDWD--DDW-DD 125

  Fly   112 NDTYSEIGPGGQKSAGQSARAGGLSHSTSDYDNKHLPIAPNDDTQSLASVAGG---TGAAGTVKK 173
            :.|..|.|...:|.|.                    |.|....|...||..|.   :.:.|||.|
Zfish   126 SGTAEEHGGTPEKRAN--------------------PQAGYSSTNPSASRRGSAQQSKSTGTVGK 170

  Fly   174 GM-----FAKS-SDSYILGLSSTKEKIPECEMAYITQVEDSIY--------QWTQNHSPYSVVVA 224
            .:     |.|| .::::||           |.:.:.:..|.|:        :|.:|...::..:.
Zfish   171 NLNRFSTFVKSGGEAFVLG-----------EASGLVRDGDKIFVVMGQSGPEWQENLYAFTCTID 224

  Fly   225 SPKKESKFKGMKTFIAYQLTPSFNNISVSRRYKHFDWLHERLVDKFCLIPVPPLPDKQISGRYEE 289
            .|.|::||||||::::|.||||.....|:|||||||||:.|||:||.:|.||.||:||.:||:||
Zfish   225 DPTKQTKFKGMKSYMSYGLTPSHTQSQVNRRYKHFDWLYARLVEKFPVISVPHLPEKQATGRFEE 289

  Fly   290 QFVEHRRVQLQEFVDWVCRHPVISKCEVWYHFLTC--RDEKIWKSGKRKAERDPYMGVNYCLAIS 352
            .|:..||..|..:::.:..|||:|||:|:.|||||  .|||.||.||||||:|..:|.|:.|.|.
Zfish   290 DFISKRRKGLIWWMNHMTSHPVLSKCDVFQHFLTCSSTDEKAWKQGKRKAEKDDLVGANFFLTIC 354

  Fly   353 PPDKNLLHSKVDAQVELGTQFIHSMDVAVRNLNNISNDMAKRSMSQSKKEFQRIGDGLSDLAKAL 417
            ||...|...:|:.:||....|...||..:..:|...|:.|::.::..|||:||:|.....|::|.
Zfish   355 PPALPLDLQEVENKVEGFKTFTKKMDENIIQVNVTINEFARKQITGFKKEYQRVGQAFRLLSQAF 419

  Fly   418 AIDERRAPTRNAVPLSESVGRIGGIFIGIGQAFGDQPKHDWIPLSDRLHIYRGVLNCFPDIFSTH 482
            .:|::...:    ||::::...|.::..||..|.:||:.|..|:||.|.||:|.|..||||....
Zfish   420 EVDQQVFSS----PLNKAMANTGEVYETIGDYFAEQPRQDLEPISDLLAIYQGHLANFPDIIHVQ 480

  Fly   483 KGAIQKRKDCEK-------LAGEGRMNNPQLHDVNRRTDVVSYTVLAELTHFKSERDTHLKHTLK 540
            |||:.|.|:.:|       .||.|         :|.|.:::|...|||:.||...|....|..::
Zfish   481 KGALTKAKESQKHGEEKDGTAGGG---------INDRCNIISCATLAEIQHFHCIRVRDFKAQMQ 536

  Fly   541 NFIAEQIKFYQGVVARLQEA 560
            .|:.:||.|:|.:..:|:||
Zfish   537 YFLQQQISFFQKITGKLEEA 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SH3PX1	NP_648348.1	SH3_SNX9_like	4..59	CDD:212697	28/55 (51%)
		PX_SNX9_18_like	219..343	CDD:132772	67/125 (54%)
		BAR_SNX9_like	362..564	CDD:153310	66/206 (32%)
snx18b	NP_001015063.1	SH3	4..58	CDD:302595	28/55 (51%)
		PX_domain	219..345	CDD:295365	67/125 (54%)
		BAR_3_WASP_bdg	328..561	CDD:287434	85/242 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4139
eggNOG	1	0.900	-	-		E1_KOG2528
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	329	1.000	Inparanoid score	I2435
OMA	1	1.010	-	-		QHG48621
OrthoDB	1	1.010	-	-		D351108at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24359
orthoMCL	1	0.900	-	-		OOG6_104281
Panther	1	1.100	-	-	O	PTHR45827
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X731
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.840