Protein Alignment SH3PX1 and snx18

DIOPT Version :10

• Sequence 1: NP_648348.1
• Gene: SH3PX1 / 39136
• FlyBaseID: FBgn0040475
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001011173.1
• Gene: snx18 / 496591
• XenbaseID: XB-GENE-958823
• Length: 585
• Species: Xenopus tropicalis
• Alignment Length: 612
• Identity: 207/612 - (33%)
• Similarity: 321/612 - (52%)
• Gaps: 76/612 - (12%)

  Fly     1 MTSYVRAMYDFTGE-PGSSELSIATGDVLSVTRSDVGEGWWEGKNARGQIGLFPAAYVEVMSAAE 64
            |....||:|||..| ||  |:|:...:|||:......|||.||.|:||:.|||||:||||:....
 Frog     1 MALRARALYDFRAENPG--EVSLRESEVLSLCSEQDIEGWLEGLNSRGERGLFPASYVEVLRGEP 63

  Fly    65 A-------QKLSASGATSVP----QVPDPFASPPLPRY---------------DQTADDDGSNWD 103
            |       ..|..|...::|    :...||.|...|:.               .|.:|||   ||
 Frog    64 AGPPPPPPPALGDSRYANLPSGGYEPAQPFQSAAAPQLGLAFQPRAPPGGYPASQPSDDD---WD 125

  Fly   104 DEDDWSDDNDTYSE---IGPGGQKSAGQSARAGGLSHSTSDYDNKHLPIAPNDDTQSLA-SVAGG 164
            ||  |.|.:.|.::   ..|||....|.....|...:..|  ....:|..|:    ||| |.|.|
 Frog   126 DE--WDDSSSTAADEPAAQPGGSYPGGYHDYEGSSRYRVS--TRSDMPPGPS----SLASSQAAG 182

  Fly   165 TGAAGTVKKGM-----FAKS-SDSYILGLSSTKEKIPECEMAYITQVEDSIY--------QWTQN 215
            .|:| ||.:.:     |.|| .::::||           |.|...:..|.:.        :|.:|
 Frog   183 KGSA-TVSRNLNRFSAFVKSGGEAFVLG-----------EAAGFVRDGDKLCVVPGAEGPEWQEN 235

  Fly   216 HSPYSVVVASPKKESKFKGMKTFIAYQLTPSFNNISVSRRYKHFDWLHERLVDKFCLIPVPPLPD 280
            ..|:...:..|.|::||||||::|:|:|.||...:.|.|||||||||:.||:|||.::.||.:|:
 Frog   236 PYPFRCSIDEPTKQTKFKGMKSYISYRLLPSHTGLQVHRRYKHFDWLYARLLDKFPVVSVPRIPE 300

  Fly   281 KQISGRYEEQFVEHRRVQLQEFVDWVCRHPVISKCEVWYHFLTCRDEKIWKSGKRKAERDPYMGV 345
            ||.:||:||.|:..|:..|..:::.:|.|||:::|:.:.|||:|.|||.||.||||.|||..:|.
 Frog   301 KQATGRFEEDFISKRKKGLVWWMEHMCSHPVLARCDAFQHFLSCTDEKAWKQGKRKCERDEMVGA 365

  Fly   346 NYCLAIS-PPDKNLLH-SKVDAQVELGTQFIHSMDVAVRNLNNISNDMAKRSMSQSKKEFQRIGD 408
            |:.|.:| ||...:|. ..||.:::....|...||..|..|:..:.:.|::..:..|||:|::|.
 Frog   366 NFFLTLSLPPGSPVLEPHDVDGRLDGFKVFTKRMDEGVLQLSQTAGEFARKQAAGFKKEYQKVGQ 430

  Fly   409 GLSDLAKALAIDERRAPTRNAVPLSESVGRIGGIFIGIGQAFGDQPKHDWIPLSDRLHIYRGVLN 473
            .:..|.:|..:|....    :..|:.::...|..:..||:.|.:||:.|..|:.|.|.:|:|.|.
 Frog   431 AVRGLGQAFEMDHMVF----SAGLNRAMAFTGEAYEAIGEMFAEQPRQDLDPIMDLLAVYQGHLA 491

  Fly   474 CFPDIFSTHKGAIQKRKDCEKLAGEGRMNNPQLHDVNRRTDVVSYTVLAELTHFKSERDTHLKHT 538
            .||||....:||:.|.::.:|...||::...:..::..|.:|:||..|||:.||...|....|..
 Frog   492 NFPDIIHVQRGALTKVRESKKQVEEGKLELQKAGEIQERCNVISYATLAEIHHFHKIRVRDFKSQ 556

  Fly   539 LKNFIAEQIKFYQGVVARLQEASRQIE 565
            :::|:.:||.|:|.|..:|:||.::.:
 Frog   557 MQHFLQQQICFFQKVTLKLEEALQKYD 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SH3PX1	NP_648348.1	SH3_SNX9_like	4..59	CDD:212697	28/55 (51%)
		PX_SNX9_18_like	219..343	CDD:132772	61/123 (50%)
		BAR_SNX9_like	362..564	CDD:153310	60/201 (30%)
snx18	NP_001011173.1	SH3_SNX18	4..58	CDD:212830	28/55 (51%)
		PX_domain	239..363	CDD:470617	61/123 (50%)
		BAR	376..582	CDD:472257	61/209 (29%)