DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SH3PX1 and SNX11

DIOPT Version :9

Sequence 1:	NP_648348.1	Gene:	SH3PX1 / 39136	FlyBaseID:	FBgn0040475	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	NP_037455.2	Gene:	SNX11 / 29916	HGNCID:	14975	Length:	270	Species:	Homo sapiens

Alignment Length:	123	Identity:	33/123 - (26%)
Similarity:	59/123 - (47%)	Gaps:	18/123 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 CEMAYITQVEDSIYQWTQNHSPYSVVVASPKKESKFKGMKTFIAYQLTPSFNNIS-------VSR 254
            |.|:...:.|:.|          :|.|..|:.::: ....:::.|::....|:.:       |.|
Human     5 CRMSENQEQEEVI----------TVRVQDPRVQNE-GSWNSYVDYKIFLHTNSKAFTAKTSCVRR 58

  Fly   255 RYKHFDWLHERLVDKFCLIPVPPLPDKQISGRYEEQFVEHRRVQLQEFVDWVCRHPVI 312
            ||:.|.||.::|.....|:|||.||.|.......::|:|.||..||.|::.|.:..|:
Human    59 RYREFVWLRKQLQRNAGLVPVPELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVVL 116

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SH3PX1	NP_648348.1	SH3_SNX9_like	4..59	CDD:212697
		PX_SNX9_18_like	219..343	CDD:132772	29/101 (29%)
		BAR_SNX9_like	362..564	CDD:153310
SNX11	NP_037455.2	PX_SNX10	18..129	CDD:132808	29/100 (29%)
		Important for membrane trafficking	135..139
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	168..203
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910