DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SH3PX1 and Snx32

DIOPT Version :9

Sequence 1:	NP_648348.1	Gene:	SH3PX1 / 39136	FlyBaseID:	FBgn0040475	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	XP_011246919.1	Gene:	Snx32 / 225861	MGIID:	2444704	Length:	461	Species:	Mus musculus

Alignment Length:	272	Identity:	52/272 - (19%)
Similarity:	103/272 - (37%)	Gaps:	71/272 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 QNHSPYSVVVA---SPKKESKF-----KGMKTFIAYQLTPSFNNISVSRRYKHFDWLHERLVDK- 269
            |..||..|.::   |.:.:.||     .|:..|       :.:..||.|:::.|.|||:..|:.
Mouse    22 QGDSPLQVEISDAVSERDKVKFTVQTKSGLPHF-------AQSEFSVVRQHEEFIWLHDTYVENE 79

  Fly   270 ----FCLIPVPPLPD--------------------KQISGRYEEQFVEH-----RRVQLQE-FVD 304
                ..:.|.||.||                    ::.|...:|...|:     :.|.:.| |:.
Mouse    80 EYAGLIIPPAPPRPDFEASREKLQKLGEGNSSITREEFSKMKQELEAEYLAIFKKTVAMHEVFLQ 144

  Fly   305 WVCRHPVISKCEVWYHF------LTCRDEK-------IWKSGKRKAERDPYMGVNYCLAIS---P 353
            .:..||.:.:...:..|      |:.|::.       :.:|..|.|:.....|::....:.   .
Mouse   145 RLAAHPTLRRDHNFSVFLEYSQDLSVREKNRKEVLGGLLRSIVRSADEVLITGISGLKEVDDFFE 209

  Fly   354 PDKNLL---HSKVDAQVELGTQFIHSMDVAVRNLNNIS---NDMAKRSMSQSKKEFQRIGDGLSD 412
            .::..|   |:::....:...:.:||......|...||   :.:..:.::|.|:.|.::.:....
Mouse   210 HERTFLVEYHTRIRDTCQRADRVMHSHKCLADNYIPISAALSSLGTQEVNQLKRSFLKLAELFER 274

  Fly   413 LAK---ALAIDE 421
            |.|   .:|.||
Mouse   275 LRKLEGRVASDE 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SH3PX1	NP_648348.1	SH3_SNX9_like	4..59	CDD:212697
		PX_SNX9_18_like	219..343	CDD:132772	33/175 (19%)
		BAR_SNX9_like	362..564	CDD:153310	13/66 (20%)
Snx32	XP_011246919.1	PX_SNX5_like	27..164	CDD:132802	28/143 (20%)
Snx32	XP_011246919.1	BAR	181..>305	CDD:386243	19/106 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845762
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840