Protein Alignment SH3PX1 and lst-4

DIOPT Version :10

• Sequence 1: NP_648348.1
• Gene: SH3PX1 / 39136
• FlyBaseID: FBgn0040475
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001379029.1
• Gene: lst-4 / 178361
• WormBaseID: WBGene00003086
• Length: 592
• Species: Caenorhabditis elegans
• Alignment Length: 511
• Identity: 178/511 - (34%)
• Similarity: 275/511 - (53%)
• Gaps: 48/511 - (9%)

  Fly    62 AAEAQKLSASGATSVPQVPDPFA-------SPPLPRYDQTADDDGSNWDDEDDWSDDNDTYSEIG 119
            ||.::.....|..|....|..:.       :|.:|...::: ....|.|.:|:|:|::|......
 Worm   107 AASSRPFDDWGGASEVAAPPSYGAQHHHQPTPSVPEVTRSS-YPSQNDDFDDEWTDEDDEQEPTR 170

  Fly   120 PGGQKSAGQSARAGGLSHSTSDYDNKHLPIAPNDDTQSLASVAGGTGAAGTVKKGM-----FAKS 179
            |..|.|.|.::|. .||.|.|::                   .|....:..|.|.:     |.||
 Worm   171 PNVQSSIGSNSRR-DLSRSHSEH-------------------GGPDRGSNKVNKNINRFSNFVKS 215

  Fly   180 S-DSYILGLSSTKEKIPECEMAYITQVEDSIYQWTQNHSPYSVVVASPKKESKFKGMKTFIAYQL 243
            . ::|::|.|.|..:|.|   .:...:.:.|.||......|:.:|..||||||.||:|:||||.:
 Worm   216 GVEAYVIGESKTTSQISE---RHEVVMNNGIIQWKPIQQYYTCIVDKPKKESKLKGLKSFIAYSI 277

  Fly   244 TPSFNNI--SVSRRYKHFDWLHERLVDKFCLIPVPPLPDKQISGRYEEQFVEHRRVQLQEFVDWV 306
            |.|..||  .|||||||||||||:|..|:.|||:||||:||::|||||..::||:..||.:|:.:
 Worm   278 TSSLTNIQRQVSRRYKHFDWLHEQLSAKYVLIPIPPLPEKQVAGRYEEDLIDHRKHILQLWVNKI 342

  Fly   307 CRHPVISKCEVWYHFLTCRDEKIWKSGKRKAERDPYMGVNYCLAISPPDKNLLHSKVDAQVELGT 371
            |||||:|:.|||.||::|.|||.||:|||:||:|.|:|..:...|:.|.:.|..:.||.|||...
 Worm   343 CRHPVLSQSEVWLHFISCTDEKDWKNGKRRAEKDEYIGGAFLNCITVPHQPLDPNNVDMQVERFQ 407

  Fly   372 QFIHSMDVAVRNLNNISNDMAKRSMSQSKKEFQRIGDGLSDLAKALAIDERRAPTRNAVPLSESV 436
            :.:.:.:.|:|.:....|...|......|:.:|::|.....|.::..|||..|..|    |:|::
 Worm   408 RSVKTSEEAMRVMQERMNMFQKVFAGPVKQNWQKMGSAFKTLQQSFEIDETVASRR----LTEAL 468

  Fly   437 GRIGGIFIGIGQAFGDQPKHDWIPLSDRLHIYRGVLNCFPDIFSTHKGAIQKRKDCEKLAGEGRM 501
            ......:..|||.|....|:|..|:.:.|:.|:|.:...|||...||.|:||.:|     .|||:
 Worm   469 AYTASEYHEIGQVFDAHTKNDMEPVLENLYSYKGTVQNVPDIIQVHKQAVQKFRD-----SEGRL 528

  Fly   502 NNPQLHDVNRRTDVVSYTVLAELTHFKSERDTHLKHTLKNFIAEQIKFYQGVVARL 557
            ::.:...:.:|.|.:||||:||:.|..:|:...:|.|:..::.:|..|||.|..:|
 Worm   529 SSAEAEKMKQRIDAMSYTVIAEVQHQTAEKVEDMKSTMGTYLKKQAMFYQEVATKL 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SH3PX1	NP_648348.1	SH3_SNX9_like	4..59	CDD:212697
		PX_SNX9_18_like	219..343	CDD:132772	76/125 (61%)
		BAR_SNX9_like	362..564	CDD:153310	60/196 (31%)
lst-4	NP_001379029.1	PX_SNX9_18_like	253..379	CDD:132772	76/125 (61%)
		BAR	362..592	CDD:472257	76/232 (33%)