Protein Alignment SH3PX1 and SH3PX1

DIOPT Version :10

• Sequence 1: NP_648348.1
• Gene: SH3PX1 / 39136
• FlyBaseID: FBgn0040475
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: XP_061516842.1
• Gene: SH3PX1 / 1280889
• VectorBaseID: AGAMI1_001078
• Length: 608
• Species: Anopheles gambiae
• Alignment Length: 600
• Identity: 319/600 - (53%)
• Similarity: 403/600 - (67%)
• Gaps: 64/600 - (10%)

  Fly     5 VRAMYDFTGEPGSSELSIATGDVLSVTRSDVGEGWWEGKNARGQIGLFPAAYVEVMSAAEAQKLS 69
            |:.:|||.|||.|||:||:..:||:||.:|||||||||.|:|||.|||||||||.:..
Mosquito    25 VKVLYDFNGEPNSSEISISVDEVLTVTNTDVGEGWWEGMNSRGQRGLFPAAYVETIPE------- 82

  Fly    70 ASGATSVPQVPDPFASPPL-------------------PRYDQTADDDGSNWDD-EDDWSDDNDT 114
               |.|:|..|.....||.                   .|||||:||.|...|| :|||.|||||
Mosquito    83 ---APSLPSGPPKMPPPPAVMAQAASGVSKSGSQQALGNRYDQTSDDWGEQQDDWDDDWDDDNDT 144

  Fly   115 YSEIGPGGQKSAGQSARAGGLSHS-----------------TSDYDNKHLPIAP--NDDTQSLAS 160
            ||||||    :|..:.|..|.:.|                 .|.|.|.:||..|  :.||.||||
Mosquito   145 YSEIGP----AAAATGRTNGQTQSYQQQQQHQQQYQQQSATASYYANANLPAPPPGDGDTMSLAS 205

  Fly   161 VA-----GGTGAAGTVKKGMFAKSSDSYILGLSSTKEKIPECEMAYITQVEDSIYQWTQNHSPYS 220
            ||     |.:.||||.|  :|.||.|:|::|:  ....:.|.:..::..:|.....|......||
Mosquito   206 VATTVGGGRSRAAGTGK--IFTKSGDNYLMGM--PVPDVSESDRVHVLLMEQGAIVWKPMRDSYS 266

  Fly   221 VVVASPKKESKFKGMKTFIAYQLTPSFNNISVSRRYKHFDWLHERLVDKFCLIPVPPLPDKQISG 285
            |.|.|||||.||.|:|:|||||||||||||.|:||||||||||||||:||||||:||||||||||
Mosquito   267 VTVDSPKKEKKFNGLKSFIAYQLTPSFNNIPVARRYKHFDWLHERLVEKFCLIPIPPLPDKQISG 331

  Fly   286 RYEEQFVEHRRVQLQEFVDWVCRHPVISKCEVWYHFLTCRDEKIWKSGKRKAERDPYMGVNYCLA 350
            ||:|:|||||||||||||||:|||||:|.|.||.|||||.|||.||:|||.||:||.:|..:|.:
Mosquito   332 RYDEEFVEHRRVQLQEFVDWMCRHPVLSTCGVWMHFLTCTDEKKWKTGKRTAEKDPLVGTMFCAS 396

  Fly   351 ISPPDKNLLHSKVDAQVELGTQFIHSMDVAVRNLNNISNDMAKRSMSQSKKEFQRIGDGLSDLAK 415
            :.||:|.||.|.|:.||:..|||:..||.||:.|..|..|.:|:...|.|||:||||:|.|::|:
Mosquito   397 VFPPEKTLLQSLVEPQVDAATQFVPQMDTAVKTLFAICGDQSKKFQQQWKKEYQRIGEGFSEMAR 461

  Fly   416 ALAIDERRAPTRNAVPLSESVGRIGGIFIGIGQAFGDQPKHDWIPLSDRLHIYRGVLNCFPDIFS 480
            |||:|||||.|:  :.|:.|||:..|:||.|||.||:|||||:||.|||||||||:|..:||...
Mosquito   462 ALAVDERRAATQ--ISLASSVGQAAGVFINIGQLFGEQPKHDFIPFSDRLHIYRGLLAAWPDTLG 524

  Fly   481 THKGAIQKRKDCEKLAGEGRMNNPQLHDVNRRTDVVSYTVLAELTHFKSERDTHLKHTLKNFIAE 545
            .::.|:||||:||:|..|.:|.|.||.:||||.||:||.:|||::||:.|||||||.|::|||..
Mosquito   525 EYRNAVQKRKECERLTAEQKMENGQLQEVNRRVDVMSYALLAEMSHFREERDTHLKDTIRNFIGA 589

  Fly   546 QIKFYQGVVARLQEA 560
            ||.||:.:|.:|::|
Mosquito   590 QIDFYKSIVQKLEQA 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SH3PX1	NP_648348.1	SH3_SNX9_like	4..59	CDD:212697	37/53 (70%)
		PX_SNX9_18_like	219..343	CDD:132772	101/123 (82%)
		BAR_SNX9_like	362..564	CDD:153310	108/198 (55%)
SH3PX1	XP_061516842.1	None