Protein Alignment CG6761 and Sanbr

DIOPT Version :10

• Sequence 1: NP_648346.1
• Gene: CG6761 / 39134
• FlyBaseID: FBgn0036031
• Length: 889
• Species: Drosophila melanogaster
• Sequence 2: NP_082136.2
• Gene: Sanbr / 71675
• MGIID: 1918925
• Length: 718
• Species: Mus musculus
• Alignment Length: 800
• Identity: 209/800 - (26%)
• Similarity: 364/800 - (45%)
• Gaps: 208/800 - (26%)

  Fly   163 NEGVLDSVLSFICPVPMPTQLQNGKTKPKQLQP---PKELLTQTSATTTPYTNPIPAAAPLTSGA 224
            |:.|||.:|..:..:|   |..|.:|..: |.|   |||.:.:.....:..::|
Mouse    16 NQMVLDMILYPLIGIP---QTINWETVAR-LVPGLTPKECVKRFDELKSCGSSP----------- 65

  Fly   225 SKSMMEIGHSHGPLPAATPSAPCLQQAHPGGDALHSDQITNSMVRA---MIKEPIPKPGAMNAGR 286
                  :.:.:.|| .||...|....|         ..|.:|::..   ..:.|:.:.....|||
Mouse    66 ------VDNQYNPL-MATGEGPVETLA---------TYIKSSLLDTQGDFQETPVDQDTVSKAGR 114

  Fly   287 RKSLLLVKD---------SKHARQERKE---PEVVIHVCDEVKNTSKDFTCPQHLLVTKMGYFAD 339
            . |:...::         :::|.:|..|   |.:|||||||.|:..:||.||:.||:::|.|||:
Mouse   115 H-SIATTRNCSSESENCTARNAGEETGESEGPNMVIHVCDEAKSLKEDFICPRDLLISEMKYFAE 178

  Fly   340 VTA--GQRLEEMDISVHCDILIFDWLMKWIK-HSAQSQDLPVPTQSTGPQLDGNNVVPILVSASF 401
            ..:  .||.||:|||||||:.||:||:|::| ::.:|:|..:|.      |:..||:.||:|:.|
Mouse   179 YLSMDAQRWEEVDISVHCDVHIFNWLIKYVKRNTKESKDCEIPA------LEPGNVISILISSEF 237

  Fly   402 LQMEPLLLECLAFCHAHLSEVVRTSTNLSCLNDALVSRLAAMFTNLELEMVRDKKERVTPRLWTK 466
            |:|:.|:.:|:.:||.:::.:|....|::|:|..|::|:|.:||:.|::.::|||::...:|:.|
Mouse   238 LKMDSLVEQCIQYCHKNMNAIVAAPCNMNCINANLLTRIADLFTHNEIDDLKDKKDKFRSKLFCK 302

  Fly   467 LIQSLCEPD---PEALRGHFYSMSGLFRCSRCFNCVTNTMKSYVSCVPSNIRLNRWGQLMSHHVR 528
            .|:.|.:|:   |::..    :.:.|:||..|...:|...:..:.|:|..|.::|.|.::..|:|
Mouse   303 KIERLFDPEYSNPDSRN----NAATLYRCCLCKKLLTRETERRIPCIPGKINVDRHGNIIYIHIR 363

  Fly   529 DTNWDLNVYIVQLFKELKSWRKVYWKLWGHCHYLYCCSCEAHFPVYQMHWCRFHPE------APN 587
            |..||::.|:..||:||||||.|||:|||..::|.|..|...|...:...|::|.|      ..|
Mouse   364 DKTWDVHEYLNSLFEELKSWRDVYWRLWGTVNWLTCSRCYQAFLCIEFSHCQYHSEVVVYSSTVN 428

  Fly   588 FLGPVGNAGPAGRFSCCGQQAFRYETLPGPNGCQFREHSVLV----ETD---------------R 633
            .|..||    .|.:.||.|:..|::......||:.|:|.|::    |.|               :
Mouse   429 SLNTVG----TGIYPCCNQKVLRFDPTQLTKGCKVRDHMVVLHDQGENDDSPSCPPAKILDDLHK 489

  Fly   634 ERAILAIAQL--------VGENYALCEQPPLRIQELAAAGEISPSWQGISLTPQRCRQGLLPQLC 690
            .:.::|:..|        ||.    |::..|..:.|     :.|:      ||...:.|.|....
Mouse   490 HKDVIAVPFLKDAVSDPGVGS----CDEKGLEYEIL-----LEPN------TPWGSKTGELNAFL 539

  Fly   691 MDSVLKRVTNHRVSRRMRGSRYQMDTSTDSETTSTSEDDARCLRPRMRNVHDDDEDYSTSSDGCE 755
            .   ||..|                                 |:.:.:::..::|:|:|.|:..|
Mouse   540 S---LKNWT---------------------------------LQLKQQSLFSEEEEYTTGSEVTE 568

  Fly   756 SE--------------HRP-----PPRK-------TRGKKSRKRPT--DVS-------GRFWSGE 785
            .|              .:|     ||:|       .:.:|:.::.|  |||       ...|...
Mouse   569 DEVGDEEEIAKKQRKKEKPKKFTKPPKKQLSSPCSQKKEKTLEKSTSRDVSPFVVSMQKNKWDAS 633

  Fly   786 LSARSNQDHQRDFEEKIMKQVANYVTKKTGTDQCLV---QNAQPLGGSYVRLESEWKEMLKQRHS 847
            .|.|.|||.||:.:::.|.::..::.|....|...|   ::.:..||.|.|||::
Mouse   634 RSLRFNQDAQREDDQRRMSEITGHLIKMRLGDLDRVKAKESKEFAGGIYSRLEAQ---------- 688

  Fly   848 HHTIQGTNATGTSVAQSNSS 867
                  ..|:....|:.|||
Mouse   689 ------VRASVPVTARQNSS 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6761	NP_648346.1	SANBR_BTB	308..412	CDD:432102	48/106 (45%)
Sanbr	NP_082136.2	SANBR_BTB	147..248	CDD:432102	48/106 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	555..622		15/66 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	690..718		4/12 (33%)