DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc4 and PEX4

DIOPT Version :9

Sequence 1:	NP_001287013.1	Gene:	Ubc4 / 39133	FlyBaseID:	FBgn0015321	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_011649.1	Gene:	PEX4 / 853034	SGDID:	S000003365	Length:	183	Species:	Saccharomyces cerevisiae

Alignment Length:	163	Identity:	54/163 - (33%)
Similarity:	82/163 - (50%)	Gaps:	27/163 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ANMAVSRIKREFKEVMR---SEEIVQCSIK--IELVN-------DSWTELRGEIAGPPDTPYEGG 54
            ::..:|||.:|:|.:::   |::.:....:  ||.:|       ..|..:   |:||.|||||..
Yeast    15 SDTCMSRIVKEYKVILKTLASDDPIANPYRGIIESLNPIDETDLSKWEAI---ISGPSDTPYENH 76

  Fly    55 KFVLEIKVPETYPFNPPKVRFI-TRIWHPNISSVTGAICLDILK-DNWAAAMTLRTVLLSLQALL 117
            :|.:.|:||.:||.||||:.|: ..|.|.|:.|.||.|||:||| :.|.....|...:.::..||
Yeast    77 QFRILIEVPSSYPMNPPKISFMQNNILHCNVKSATGEICLNILKPEEWTPVWDLLHCVHAVWRLL 141

  Fly   118 AAAEPDDPQDAVV----------AYQFKDKYDL 140
            .....|.|.|..:          |||...||.|
Yeast   142 REPVCDSPLDVDIGNIIRCGDMSAYQGIVKYFL 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc4	NP_001287013.1	COG5078	1..153	CDD:227410	54/163 (33%)
		UQ_con	8..149	CDD:278603	53/157 (34%)
		UBA_II_E2_UBCD4	163..198	CDD:270574
PEX4	NP_011649.1	COG5078	15..176	CDD:227410	54/163 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S653
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950