DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc4 and UBE2D2

DIOPT Version :9

Sequence 1:	NP_001287013.1	Gene:	Ubc4 / 39133	FlyBaseID:	FBgn0015321	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	XP_016865309.1	Gene:	UBE2D2 / 7322	HGNCID:	12475	Length:	173	Species:	Homo sapiens

Alignment Length:	130	Identity:	60/130 - (46%)
Similarity:	77/130 - (59%)	Gaps:	3/130 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QCSIKIELVNDSWTELRGEIAGPPDTPYEGGKFVLEIKVPETYPFNPPKVRFITRIWHPNISSVT 88
            |||  ...|.|.....:..|.||.|:||:||.|.|.|..|..|||.||||.|.|||:||||:| .
Human    46 QCS--AGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINS-N 107

  Fly    89 GAICLDILKDNWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVAYQFKDKYDLFLLTAKHWTNAYA 153
            |:||||||:..|:.|:|:..||||:.:||....||||....:|..:|...:.:...|:.||..||
Human   108 GSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYA 172

Fly 154 153
Human 173 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc4	NP_001287013.1	COG5078	1..153	CDD:227410	58/128 (45%)
		UQ_con	8..149	CDD:278603	56/124 (45%)
		UBA_II_E2_UBCD4	163..198	CDD:270574
UBE2D2	XP_016865309.1	COG5078	35..173	CDD:227410	60/130 (46%)
UBE2D2	XP_016865309.1	UBCc	35..172	CDD:294101	58/128 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910