DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc4 and ube2e2

DIOPT Version :9

Sequence 1:	NP_001287013.1	Gene:	Ubc4 / 39133	FlyBaseID:	FBgn0015321	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001003494.1	Gene:	ube2e2 / 445100	ZFINID:	ZDB-GENE-040801-237	Length:	201	Species:	Danio rerio

Alignment Length:	152	Identity:	66/152 - (43%)
Similarity:	87/152 - (57%)	Gaps:	10/152 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 AVSRIKREFKEVMRSEEIVQCSIKIELVNDSWTELRGEIAGPPDTPYEGGKFVLEIKVPETYPFN 69
            :..||::|..|: ..:....||...:  .|:..|.|..|.|||.:.||||.|.|:|.....|||.
Zfish    56 SAKRIQKELAEI-TLDPPPNCSAGPK--GDNIYEWRSTILGPPGSVYEGGVFFLDIAFTPDYPFK 117

  Fly    70 PPKVRFITRIWHPNISSVTGAICLDILKDNWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVAYQF 134
            ||||.|.|||:|.||:| .|.||||||||||:.|:|:..||||:.:||....|.||....:|.|:
Zfish   118 PPKVTFRTRIYHCNINS-QGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQY 181

  Fly   135 ---KDKYDLFLLTAKHWTNAYA 153
               :.::|..   ||.||..||
Zfish   182 LTNRTEHDRI---AKQWTKRYA 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc4	NP_001287013.1	COG5078	1..153	CDD:227410	64/150 (43%)
		UQ_con	8..149	CDD:278603	62/143 (43%)
		UBA_II_E2_UBCD4	163..198	CDD:270574
ube2e2	NP_001003494.1	UQ_con	59..196	CDD:395127	62/143 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910