DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc4 and Ubc7

DIOPT Version :9

Sequence 1:	NP_001287013.1	Gene:	Ubc4 / 39133	FlyBaseID:	FBgn0015321	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001285334.1	Gene:	Ubc7 / 44054	FlyBaseID:	FBgn0267384	Length:	167	Species:	Drosophila melanogaster

Alignment Length:	173	Identity:	53/173 - (30%)
Similarity:	84/173 - (48%)	Gaps:	24/173 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MANMAVSRIKREFKEVMRS--EEIVQCSIKIELVNDSWTELRGEIAGPPDTPYEGGKFVLEIKVP 63
            ||..|:.|:..|:|::...  |.||...|.    .|::.|....||||..|.:|||.|...:..|
  Fly     1 MAGSALRRLMAEYKQLTLDPPEGIVAGPIS----EDNFFEWEALIAGPEGTCFEGGVFPARLIFP 61

  Fly    64 ETYPFNPPKVRFITRIWHPNISSVTGAICLDIL-------------KDNWAAAMTLRTVLLSLQA 115
            ..||.:|||::|...::||||.: .|.:|:.||             .:.|:...::..:|||:.:
  Fly    62 TDYPLSPPKMKFTCDMFHPNIFA-DGRVCISILHAPGDDPMGYELSAERWSPVQSVEKILLSVVS 125

  Fly   116 LLAAAEPDDPQDAVV--AYQFKDKYDLFLLTAKHWTNAYAGGP 156
            :|  |||:|...|.|  |..::::.|.|...|:.......|.|
  Fly   126 ML--AEPNDESGANVDAAIMWREQRDEFNAIARRLVRKTLGLP 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc4	NP_001287013.1	COG5078	1..153	CDD:227410	51/168 (30%)
		UQ_con	8..149	CDD:278603	48/157 (31%)
		UBA_II_E2_UBCD4	163..198	CDD:270574
Ubc7	NP_001285334.1	COG5078	1..163	CDD:227410	51/168 (30%)
Ubc7	NP_001285334.1	UQ_con	8..159	CDD:278603	48/157 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438048
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930