DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc4 and ube2kb

DIOPT Version :9

Sequence 1:	NP_001287013.1	Gene:	Ubc4 / 39133	FlyBaseID:	FBgn0015321	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001008611.1	Gene:	ube2kb / 30100	ZFINID:	ZDB-GENE-980605-9	Length:	200	Species:	Danio rerio

Alignment Length:	199	Identity:	135/199 - (67%)
Similarity:	165/199 - (82%)	Gaps:	0/199 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MANMAVSRIKREFKEVMRSEEIVQCSIKIELVNDSWTELRGEIAGPPDTPYEGGKFVLEIKVPET 65
            |||:||.|||||||||::|||..:..||::||::::|||:||||||||||||||::.||||:|||
Zfish     1 MANIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELKGEIAGPPDTPYEGGRYQLEIKIPET 65

  Fly    66 YPFNPPKVRFITRIWHPNISSVTGAICLDILKDNWAAAMTLRTVLLSLQALLAAAEPDDPQDAVV 130
            ||||||||||||:||||||||||||||||||||.|||||||||||||||||||||||||||||||
Zfish    66 YPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVV 130

  Fly   131 AYQFKDKYDLFLLTAKHWTNAYAGGPHTFPDCDSKIQRLRDMGIDEHEARAVLSKENWNLEKATE 195
            |.|:|...::|..||:.|::.|||.|.:.|:...||.:|..||.|::.....||.::|::|.|||
Zfish   131 ANQYKQNPEMFKQTARLWSHVYAGAPVSSPEYTRKIDKLCAMGFDKNAVIVALSSKSWDVETATE 195

  Fly   196 GLFS 199
            .|.|
Zfish   196 LLLS 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc4	NP_001287013.1	COG5078	1..153	CDD:227410	115/151 (76%)
		UQ_con	8..149	CDD:278603	109/140 (78%)
		UBA_II_E2_UBCD4	163..198	CDD:270574	13/34 (38%)
ube2kb	NP_001008611.1	UBCc	6..148	CDD:238117	110/141 (78%)
ube2kb	NP_001008611.1	UBA_II_E2_UBE2K	163..200	CDD:270573	15/37 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596841
Domainoid	1	1.000	228	1.000	Domainoid score	I2423
eggNOG	1	0.900	-	-		E2759_KOG0418
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3903
Inparanoid	1	1.050	263	1.000	Inparanoid score	I3075
OMA	1	1.010	-	-		QHG57104
OrthoDB	1	1.010	-	-		D1418652at2759
OrthoFinder	1	1.000	-	-		FOG0003491
OrthoInspector	1	1.000	-	-		otm26266
orthoMCL	1	0.900	-	-		OOG6_103192
Panther	1	1.100	-	-	O	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4349
SonicParanoid	1	1.000	-	-		X2383
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800