DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc4 and Ube2a

DIOPT Version :9

Sequence 1:	NP_001287013.1	Gene:	Ubc4 / 39133	FlyBaseID:	FBgn0015321	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001013955.1	Gene:	Ube2a / 298317	RGDID:	1359534	Length:	162	Species:	Rattus norvegicus

Alignment Length:	156	Identity:	46/156 - (29%)
Similarity:	76/156 - (48%)	Gaps:	34/156 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MANMAVSRIKREFKEVMR----------SEEIVQCSIKIELVNDSWTELRGEIAGPPDTPYEG-- 53
            |:..|..|:.|:||.:..          ||..:..          |..:   |.||..||:|.
  Rat     1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMV----------WNAV---IFGPEGTPFEDGT 52

  Fly    54 --------GKFVLEIKVPETYPFNPPKVRFITRIWHPNISSVTGAICLDILKDNWAAAMTLRTVL 110
                    |.|.|.|:..|.||..||.|||:::::|||:.: .|:||||||::.|:....:.::|
  Rat    53 HVETTGQLGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYA-DGSICLDILQNRWSPTYDVSSIL 116

  Fly   111 LSLQALLAAAEPDDPQDAVVAYQFKD 136
            .|:|:||....|:.|.::..|..:::
  Rat   117 TSIQSLLDEPNPNSPANSQAAQLYQE 142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc4	NP_001287013.1	COG5078	1..153	CDD:227410	46/156 (29%)
		UQ_con	8..149	CDD:278603	44/149 (30%)
		UBA_II_E2_UBCD4	163..198	CDD:270574
Ube2a	NP_001013955.1	UQ_con	8..155	CDD:395127	44/149 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000