DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc4 and ubc-20

DIOPT Version :9

Sequence 1:	NP_001287013.1	Gene:	Ubc4 / 39133	FlyBaseID:	FBgn0015321	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_497174.1	Gene:	ubc-20 / 175185	WormBaseID:	WBGene00006715	Length:	199	Species:	Caenorhabditis elegans

Alignment Length:	199	Identity:	106/199 - (53%)
Similarity:	148/199 - (74%)	Gaps:	0/199 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MANMAVSRIKREFKEVMRSEEIVQCSIKIELVNDSWTELRGEIAGPPDTPYEGGKFVLEIKVPET 65
            |:|:|.:|::||.|||:.:.||.:..|.||::|::.||::|.|.|||||||.||.|.|:||:|:.
Worm     1 MSNIAFNRLQRECKEVVTNSEISETGIMIEILNENLTEIKGHIRGPPDTPYAGGMFDLDIKIPDQ 65

  Fly    66 YPFNPPKVRFITRIWHPNISSVTGAICLDILKDNWAAAMTLRTVLLSLQALLAAAEPDDPQDAVV 130
            |||:||.|:|.|:|||||:||.||.||||||||.|||::||||||||:|||:...||.|||||||
Worm    66 YPFSPPNVKFSTKIWHPNVSSQTGVICLDILKDQWAASLTLRTVLLSIQALMCTPEPKDPQDAVV 130

  Fly   131 AYQFKDKYDLFLLTAKHWTNAYAGGPHTFPDCDSKIQRLRDMGIDEHEARAVLSKENWNLEKATE 195
            |.|:.:|..:|..||::||..:|.|........:.:.:|:|||:.|.||.:|||..||::.::|.
Worm   131 AKQYMEKPAVFKATAEYWTTKFAKGAVKNAGYQALVDKLKDMGVREEEAVSVLSCNNWDINRSTV 195

  Fly   196 GLFS 199
            .:||
Worm   196 YIFS 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc4	NP_001287013.1	COG5078	1..153	CDD:227410	89/151 (59%)
		UQ_con	8..149	CDD:278603	84/140 (60%)
		UBA_II_E2_UBCD4	163..198	CDD:270574	13/34 (38%)
ubc-20	NP_497174.1	UQ_con	8..149	CDD:365926	84/140 (60%)
ubc-20	NP_497174.1	UBA_II_E2_UBE2K_like	163..198	CDD:270498	13/34 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	181	1.000	Domainoid score	I2065
eggNOG	1	0.900	-	-		E2759_KOG0418
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3903
Inparanoid	1	1.050	228	1.000	Inparanoid score	I2212
Isobase	1	0.950	-	0	Normalized mean entropy	S653
OMA	1	1.010	-	-		QHG57104
OrthoDB	1	1.010	-	-		D1418652at2759
OrthoFinder	1	1.000	-	-		FOG0003491
OrthoInspector	1	1.000	-	-		otm14296
orthoMCL	1	0.900	-	-		OOG6_103192
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4349
SonicParanoid	1	1.000	-	-		X2383
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.860